General information for g8087.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Proteasome subunit beta type-7.
Parent gene
- The parent gene g8087 is located on chr_2: 28534763..28535526 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8087 | g8087.t3 | TSS | g8087.t3 | 28534491 | 28534491 |
| chr_2 | g8087 | g8087.t3 | isoform | g8087.t3 | 28534620 | 28535526 |
| chr_2 | g8087 | g8087.t3 | exon | g8087.t3.exon1 | 28534620 | 28534681 |
| chr_2 | g8087 | g8087.t3 | cds | g8087.t3.CDS1 | 28534620 | 28534681 |
| chr_2 | g8087 | g8087.t3 | exon | g8087.t3.exon2 | 28534764 | 28534995 |
| chr_2 | g8087 | g8087.t3 | cds | g8087.t3.CDS2 | 28534764 | 28534995 |
| chr_2 | g8087 | g8087.t3 | exon | g8087.t3.exon3 | 28535092 | 28535437 |
| chr_2 | g8087 | g8087.t3 | cds | g8087.t3.CDS3 | 28535092 | 28535437 |
| chr_2 | g8087 | g8087.t3 | exon | g8087.t3.exon4 | 28535486 | 28535526 |
| chr_2 | g8087 | g8087.t3 | cds | g8087.t3.CDS4 | 28535486 | 28535526 |
| chr_2 | g8087 | g8087.t3 | TTS | g8087.t3 | 28535595 | 28535595 |
Sequences
>g8087.t3 Gene=g8087 Length=681
ATGAATAGTGTTTTAGCACCTGAAATTGAACAACATGGATTTAACTTCTCTAATTGTCGC
AGAAATGAAAAACTCATTCATGATGGATTTAAACCACCTAAAGCTACTAAAACAGGAACC
ACTATTGTTGGAATTATCTATAAACATGGAGTAATTTTGGGTGCTGATACTAGAGCAACA
AGCGGAAATATTGTGAGCGATAAAAATTGCGAGAAAATTCACTTCTTGGCAAAAAATATG
TACTGCTGTGGAGCTGGAACAGCAGCTGATACTGAAATGACAACAAAAATGATTGGTCAT
GTAAGTGCTGCTCTTGTTCTTGGTGGTGTTGATAATCAAGGACCTCATATCTATTGCATC
TATCCACACGGATCAACTGATAAACTTCCATATGCTACAATGGGCTCAGGTTCTTTAGCC
GCTATGTCGGTATTTGAGTCGCGTTGGAAACCAGATATGGAAGAAGAGGAAGGCAAGAAA
CTTGTTCGTGATGCAATTGCTGCTGGTATTTTCAATGACCTTGGATCAGGTTCTAATGTA
GACCTGTGTATTATCCGAAAAGATTCCACTCAATATTTACGCAATTATGAATTGGCTAAT
GAGAAAGGTGTTAGAAATTTGGATTATACATATAAGCGAGAAGAATCAACATCCGGCATT
GAAAAAATGGACACAAATTAA
>g8087.t3 Gene=g8087 Length=226
MNSVLAPEIEQHGFNFSNCRRNEKLIHDGFKPPKATKTGTTIVGIIYKHGVILGADTRAT
SGNIVSDKNCEKIHFLAKNMYCCGAGTAADTEMTTKMIGHVSAALVLGGVDNQGPHIYCI
YPHGSTDKLPYATMGSGSLAAMSVFESRWKPDMEEEEGKKLVRDAIAAGIFNDLGSGSNV
DLCIIRKDSTQYLRNYELANEKGVRNLDYTYKREESTSGIEKMDTN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g8087.t3 | CDD | cd03763 | proteasome_beta_type_7 | 40 | 196 | 4.18946E-108 |
| 9 | g8087.t3 | Gene3D | G3DSA:3.60.20.10 | Glutamine Phosphoribosylpyrophosphate | 40 | 97 | 1.3E-23 |
| 10 | g8087.t3 | Gene3D | G3DSA:3.60.20.10 | Glutamine Phosphoribosylpyrophosphate | 98 | 225 | 7.2E-41 |
| 3 | g8087.t3 | PANTHER | PTHR11599:SF42 | PROTEASOME SUBUNIT BETA TYPE-7 | 20 | 99 | 2.4E-84 |
| 5 | g8087.t3 | PANTHER | PTHR11599 | PROTEASOME SUBUNIT ALPHA/BETA | 20 | 99 | 2.4E-84 |
| 4 | g8087.t3 | PANTHER | PTHR11599:SF42 | PROTEASOME SUBUNIT BETA TYPE-7 | 99 | 200 | 2.4E-84 |
| 6 | g8087.t3 | PANTHER | PTHR11599 | PROTEASOME SUBUNIT ALPHA/BETA | 99 | 200 | 2.4E-84 |
| 1 | g8087.t3 | Pfam | PF00227 | Proteasome subunit | 37 | 98 | 1.8E-17 |
| 2 | g8087.t3 | Pfam | PF00227 | Proteasome subunit | 99 | 185 | 3.7E-20 |
| 8 | g8087.t3 | ProSitePatterns | PS00854 | Proteasome beta-type subunits signature. | 43 | 90 | - |
| 7 | g8087.t3 | SUPERFAMILY | SSF56235 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 9 | 200 | 3.46E-56 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0051603 | proteolysis involved in cellular protein catabolic process | BP |
| GO:0004298 | threonine-type endopeptidase activity | MF |
| GO:0005839 | proteasome core complex | CC |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
