General information for g8180.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Epsin-2.
Parent gene
- The parent gene g8180 is located on chr_2: 28944155..28947288 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8180 | g8180.t1 | TSS | g8180.t1 | 28944125 | 28944125 |
| chr_2 | g8180 | g8180.t1 | isoform | g8180.t1 | 28944155 | 28947288 |
| chr_2 | g8180 | g8180.t1 | exon | g8180.t1.exon1 | 28944155 | 28944223 |
| chr_2 | g8180 | g8180.t1 | cds | g8180.t1.CDS1 | 28944155 | 28944223 |
| chr_2 | g8180 | g8180.t1 | exon | g8180.t1.exon2 | 28944339 | 28945136 |
| chr_2 | g8180 | g8180.t1 | cds | g8180.t1.CDS2 | 28944339 | 28945136 |
| chr_2 | g8180 | g8180.t1 | exon | g8180.t1.exon3 | 28945189 | 28945569 |
| chr_2 | g8180 | g8180.t1 | cds | g8180.t1.CDS3 | 28945189 | 28945569 |
| chr_2 | g8180 | g8180.t1 | exon | g8180.t1.exon4 | 28945623 | 28946012 |
| chr_2 | g8180 | g8180.t1 | cds | g8180.t1.CDS4 | 28945623 | 28946012 |
| chr_2 | g8180 | g8180.t1 | exon | g8180.t1.exon5 | 28946076 | 28946198 |
| chr_2 | g8180 | g8180.t1 | cds | g8180.t1.CDS5 | 28946076 | 28946198 |
| chr_2 | g8180 | g8180.t1 | exon | g8180.t1.exon6 | 28947226 | 28947288 |
| chr_2 | g8180 | g8180.t1 | cds | g8180.t1.CDS6 | 28947226 | 28947288 |
| chr_2 | g8180 | g8180.t1 | TTS | g8180.t1 | 28947703 | 28947703 |
Sequences
>g8180.t1 Gene=g8180 Length=1824
ATGCAGATGAACGTAGCTGGCCTGCGAAGAAATATAAAGAACCTGGCACATAATTATAGC
GATGCTCAGGTAAAAGTAAGAGAAGCAACATCAAATGATCCTTGGGGACCATCCTCAACT
TTAATGGCAGAAATTGCAGATCTAACTTATAACGTTGTTGCCTTTTCTGAGATTATGCAA
ATGATATGGAAGCGAACAAATGATCATGGCAAAAATTGGCGTCATGTTTATAAAGCACTC
TTGTTATTAGAATATCTTATAAAGACGGGTTCTGAGAAAGTTGCACAACAATGTAAGGAA
AATATTTTTTCAATTCAAACACTGAAGGATTTTCAACATTTGGAAGAAGGAAAAGATCAG
GGTGTACATGTACGTGAGAAGGCAAAACAACTTGTAACTTTATTAAAGGATGATGAACGA
TTAAAAGCAGAAAGAGCGCGAGCTTTGAAAGCAAAAGAGCGATTTGCTAGAACTGCATCT
GGTTTTGGCAGTGATGGATCAATAGATGGGCCTAGTAGAGATCGAGATACACCTGTTTGG
CCAGAATCAGATAGGAGAAGTGTTACTAATGATGTTGATTTTGTTAGACCAACAACTGTT
GGAGAGGAAGAACTGCAATTGCAATTAGCTATAGCTATGTCTAAAGAAGAAGCCGAGCAA
GAGGAATCAAAAAGACGCTCAGATGATGTTAGATTACAACTTGCACTTAGTCAAAGTGAA
CAAGACTTTAAGAAACAAGGCGAGAAAAAGGAGAGTGCTTTAGTAGATTTGTTAGATATT
TCTTTCGGTGCGACAGGAATTTCTAGTCCAGCACAGCAAGATCCATGGGGTATGCCATCT
CAGCAACAAGCATCAACTCGTACAATGAGTAATGATATAGGATGGTCAACGAAACCTGCT
GATCCTTGGCTCCCTCCTCCTCCTATGAGTAATGGATCATCTGCTGCTTCAGCTTTTCCA
TTATCGTCTGAACAAAGTCTTGGTGCTCGTACAAAATCACCAGCTGGTAACTCGAGTTCA
TCAATTGAAGGATGGCTTCAAAATGTTCCACCACCAACATCAAATGCAGTTCCTGTTTTA
CCCGCAAAACCACAATCAAATTCTCATGAATTGAGTGATTGGTCAGTTAAACCAGATCCT
TGGAAGCAACCTTCTCAACAGCAGCAACAACAAGTGCCTGATCCATGGAACTTAAAGACT
TCAAATGATGACCCTTGGGCACCAATTGGCGATAATAAAGCTAGTGGATTTCCTGCACCT
TCATCTTCTGGAATACGCCAAACAAACAGTGCTCTAGGTGGCCTCACACCAGGATCAGAC
TTAGATGAATTTGATATAATTACCAATCGCAGTAAATCGGCACAACAAGCAACTTCATCT
CCTATTAATGATATGCTAAATCGTCAAAATAATAATAACCTAAATGATTTACTTGCTGAT
ATGGATCCACTCAATACTAAAAACAAGCCAGTCGCAACGAAAAACAATCCAGCAGCATTT
CTTGGTGAAAACTCATCTTTGGTCAATTTGGATAACTTGATAAAACCTATGAATCAAACA
AGTAATAATAACGCATACAATCCATTTAGTGATTCGCCGGCAAATAAAAAGAATTTATTT
CATCAAAATCAACCACAGAACCCGTCCATGAATCAATTAAAACAACAACAGCAATTTCAA
GTTGCTTCTTCACTTACACAACAACAGCCACAACAAGATCCTTGGGGTTTACCCGTTAAT
AACAACGATTCAAATCAGCAGAACACCATCAACAATAATAACATCGGATGGATGAATCCA
AATCAATCAAATCCTTTTCTGTAA
>g8180.t1 Gene=g8180 Length=607
MQMNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSSTLMAEIADLTYNVVAFSEIMQ
MIWKRTNDHGKNWRHVYKALLLLEYLIKTGSEKVAQQCKENIFSIQTLKDFQHLEEGKDQ
GVHVREKAKQLVTLLKDDERLKAERARALKAKERFARTASGFGSDGSIDGPSRDRDTPVW
PESDRRSVTNDVDFVRPTTVGEEELQLQLAIAMSKEEAEQEESKRRSDDVRLQLALSQSE
QDFKKQGEKKESALVDLLDISFGATGISSPAQQDPWGMPSQQQASTRTMSNDIGWSTKPA
DPWLPPPPMSNGSSAASAFPLSSEQSLGARTKSPAGNSSSSIEGWLQNVPPPTSNAVPVL
PAKPQSNSHELSDWSVKPDPWKQPSQQQQQQVPDPWNLKTSNDDPWAPIGDNKASGFPAP
SSSGIRQTNSALGGLTPGSDLDEFDIITNRSKSAQQATSSPINDMLNRQNNNNLNDLLAD
MDPLNTKNKPVATKNNPAAFLGENSSLVNLDNLIKPMNQTSNNNAYNPFSDSPANKKNLF
HQNQPQNPSMNQLKQQQQFQVASSLTQQQPQQDPWGLPVNNNDSNQQNTINNNNIGWMNP
NQSNPFL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g8180.t1 | CDD | cd16990 | ENTH_Epsin | 21 | 142 | 4.48053E-92 |
| 8 | g8180.t1 | Coils | Coil | Coil | 5 | 32 | - |
| 7 | g8180.t1 | Gene3D | G3DSA:1.25.40.90 | - | 1 | 145 | 3.4E-66 |
| 16 | g8180.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 160 | 188 | - |
| 17 | g8180.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 169 | 188 | - |
| 15 | g8180.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 266 | 290 | - |
| 18 | g8180.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 310 | 342 | - |
| 14 | g8180.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 363 | 397 | - |
| 13 | g8180.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 547 | 572 | - |
| 3 | g8180.t1 | PANTHER | PTHR12276:SF16 | EPSIN-3 | 6 | 247 | 2.4E-125 |
| 5 | g8180.t1 | PANTHER | PTHR12276 | EPSIN/ENT-RELATED | 6 | 247 | 2.4E-125 |
| 2 | g8180.t1 | PANTHER | PTHR12276:SF16 | EPSIN-3 | 248 | 561 | 2.4E-125 |
| 4 | g8180.t1 | PANTHER | PTHR12276 | EPSIN/ENT-RELATED | 248 | 561 | 2.4E-125 |
| 1 | g8180.t1 | Pfam | PF01417 | ENTH domain | 19 | 141 | 2.1E-48 |
| 19 | g8180.t1 | ProSiteProfiles | PS50942 | ENTH domain profile. | 14 | 145 | 44.624 |
| 20 | g8180.t1 | ProSiteProfiles | PS50330 | Ubiquitin-interacting motif (UIM) domain profile. | 202 | 221 | 11.936 |
| 21 | g8180.t1 | ProSiteProfiles | PS50330 | Ubiquitin-interacting motif (UIM) domain profile. | 227 | 246 | 8.646 |
| 10 | g8180.t1 | SMART | SM00273 | enth_2 | 20 | 145 | 4.5E-60 |
| 11 | g8180.t1 | SMART | SM00726 | uim | 202 | 221 | 0.053 |
| 12 | g8180.t1 | SMART | SM00726 | uim | 227 | 246 | 5.6 |
| 6 | g8180.t1 | SUPERFAMILY | SSF48464 | ENTH/VHS domain | 5 | 145 | 2.47E-52 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K12471 (epsin)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
