Gene loci information

Transcript annotation

  • This transcript has been annotated as Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g823 g823.t12 isoform g823.t12 6266352 6269939
chr_3 g823 g823.t12 exon g823.t12.exon1 6266352 6266366
chr_3 g823 g823.t12 cds g823.t12.CDS1 6266353 6266366
chr_3 g823 g823.t12 exon g823.t12.exon2 6266441 6266801
chr_3 g823 g823.t12 cds g823.t12.CDS2 6266441 6266801
chr_3 g823 g823.t12 exon g823.t12.exon3 6268390 6268467
chr_3 g823 g823.t12 cds g823.t12.CDS3 6268390 6268419
chr_3 g823 g823.t12 exon g823.t12.exon4 6269929 6269939
chr_3 g823 g823.t12 TSS g823.t12 6270055 6270055
chr_3 g823 g823.t12 TTS g823.t12 NA NA

Sequences

>g823.t12 Gene=g823 Length=465
ACTTGTTTATTATTAAAAATTTATCGTCTTAAAAATAATCAACTGATAAAGAATTAATCA
TGTCGCTCTTCAGAATCGCATCAGCGGAGGTACGCAATGTTATCAAGCGCTCATATAACA
CCACAAATGTCGCACCCACTGTCAAAATGTTCATTGATGGAAAATTTGTTGATTCACAAG
CCAAAGAATGGATTGATTTACATGATCCAGCAACAAATGAGCTTGTAACACGCGTTCCAA
AGTGCACTCTTGATGAAATGAATGCTGCTGTTGAATCATCGAAACGCGCTTTTAAGACAT
GGAGTCAAACATCAATTCTTACACGTCAGCAAGTCATGCTCAAATTGCAGCATATTATTC
GCGCCAATATGTCTGAATTAGCTAAGAATATTACAAAAGAACAGGGAAAAACACTTGTCG
ATGCTGAAGGCGATGTTTTAAGAGGATTGCAGGTTGTTGAGCACA

>g823.t12 Gene=g823 Length=135
MSLFRIASAEVRNVIKRSYNTTNVAPTVKMFIDGKFVDSQAKEWIDLHDPATNELVTRVP
KCTLDEMNAAVESSKRAFKTWSQTSILTRQQVMLKLQHIIRANMSELAKNITKEQGKTLV
DAEGDVLRGLQVVEH

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g823.t12 Gene3D G3DSA:3.40.605.10 Aldehyde Dehydrogenase; Chain A 9 135 0
2 g823.t12 PANTHER PTHR43866:SF3 METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL 8 135 0
3 g823.t12 PANTHER PTHR43866 MALONATE-SEMIALDEHYDE DEHYDROGENASE 8 135 0
1 g823.t12 Pfam PF00171 Aldehyde dehydrogenase family 36 134 0
4 g823.t12 SUPERFAMILY SSF53720 ALDH-like 12 134 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0004491 methylmalonate-semialdehyde dehydrogenase (acylating) activity MF
GO:0055114 NA NA
GO:0016491 oxidoreductase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values