General information for g823.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial.
Parent gene
- The parent gene g823 is located on chr_3: 6266468..6270027 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g823 | g823.t3 | TTS | g823.t3 | 6263611 | 6263611 |
| chr_3 | g823 | g823.t3 | isoform | g823.t3 | 6263835 | 6264797 |
| chr_3 | g823 | g823.t3 | exon | g823.t3.exon1 | 6263835 | 6263949 |
| chr_3 | g823 | g823.t3 | exon | g823.t3.exon2 | 6264346 | 6264797 |
| chr_3 | g823 | g823.t3 | cds | g823.t3.CDS1 | 6264346 | 6264609 |
| chr_3 | g823 | g823.t3 | TSS | g823.t3 | NA | NA |
Sequences
>g823.t3 Gene=g823 Length=567
GAGACAAACCCGGTGTTGATCTCGGTCCAGTCATTTCACCACAATCAAAGAAACGTATTC
TCGATCTTGTGCAGTCAGGCGTCGATGAAGGCGCGAAAATCGTCCTTGATGGACGTGACA
TTAAAATTGATGGCTATGAAAAGGGTAACTTTGTTGGACCAACAATTCTCGTCAATGTGA
CGCCTTCAATGAAATGCTATAAAGAAGAAATTTTCGGACCAGTTCTTGTATGTTTAACGG
CAGAGACGCTTGATGAAGCCATTGACATCATTAATAAGAACCCATACGGCAATGGCACAG
CTATTTTCACAACGAATGGCGCGACAGCGAGGAAATTTGTCAATGAAATTGATGTTGGAC
AAGTTGGCGTTAATGTTCCCATTCCTGTGCCATTACCAATGTTCTCATTCACTGGATCAC
GTGGTAGTTTCTGGGGCTCAGAACATTTGTAACTACGGTAAGCAAGGCATCAAGTTCTAT
ACCCAAACGAAGACGGTTACTCAATTGTGGCGCGAGACAGATGTGACGCATACTCAAGCA
GCAGTTGCCATGCCCACAATGAAATAA
>g823.t3 Gene=g823 Length=87
MKCYKEEIFGPVLVCLTAETLDEAIDIINKNPYGNGTAIFTTNGATARKFVNEIDVGQVG
VNVPIPVPLPMFSFTGSRGSFWGSEHL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g823.t3 | Gene3D | G3DSA:3.40.309.10 | Aldehyde Dehydrogenase; Chain A | 1 | 87 | 0 |
| 2 | g823.t3 | PANTHER | PTHR43866:SF3 | METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL | 1 | 86 | 0 |
| 3 | g823.t3 | PANTHER | PTHR43866 | MALONATE-SEMIALDEHYDE DEHYDROGENASE | 1 | 86 | 0 |
| 1 | g823.t3 | Pfam | PF00171 | Aldehyde dehydrogenase family | 1 | 85 | 0 |
| 4 | g823.t3 | SUPERFAMILY | SSF53720 | ALDH-like | 1 | 86 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | MF |
| GO:0004491 | methylmalonate-semialdehyde dehydrogenase (acylating) activity | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
