Gene loci information

Transcript annotation

  • This transcript has been annotated as Histone H3.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g8296 g8296.t1 TTS g8296.t1 29597873 29597873
chr_2 g8296 g8296.t1 isoform g8296.t1 29598007 29598354
chr_2 g8296 g8296.t1 exon g8296.t1.exon1 29598007 29598354
chr_2 g8296 g8296.t1 cds g8296.t1.CDS1 29598007 29598354
chr_2 g8296 g8296.t1 TSS g8296.t1 29598406 29598406

Sequences

>g8296.t1 Gene=g8296 Length=348
ATGGCTCGTACAAAGCAGACAGCTCGTAAATCAACTGGAGGTAAAGCACCTCGTAAGCAA
TTGGCCACAAAGGCTGCTCGCAAATCAGCACCAGCAACTGGAGGAGTCAAAAAACCACAT
CGTTATCGTCCAGGAACAGTCGCTCTTCGTGAAATTCGTCGTTACCAAAAATCAACTGAA
TTGCTCATCCGCAAATTGCCTTTCCAACGCTTAGTTCGTGAAATTGCTCAAGATTTCAAA
ACTGATTTGCGTTTCCAATCATCAGCAGTTATGGCATTGCAAGAAGCATCAGAAGCTTAT
TTGGTTGGTCTCTTCGAAAGATACAAACTTGTGCGCCATTCATGCTAA

>g8296.t1 Gene=g8296 Length=115
MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTE
LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFERYKLVRHSC

Protein features from InterProScan

Transcript Database ID Name Start End E.value
11 g8296.t1 Gene3D G3DSA:1.10.20.10 Histone 2 114 4.3E-59
15 g8296.t1 MobiDBLite mobidb-lite consensus disorder prediction 1 43 -
2 g8296.t1 PANTHER PTHR11426 HISTONE H3 1 110 4.0E-72
3 g8296.t1 PANTHER PTHR11426:SF198 - 1 110 4.0E-72
5 g8296.t1 PRINTS PR00622 Histone H3 signature 3 17 1.5E-62
7 g8296.t1 PRINTS PR00622 Histone H3 signature 17 31 1.5E-62
9 g8296.t1 PRINTS PR00622 Histone H3 signature 34 55 1.5E-62
4 g8296.t1 PRINTS PR00622 Histone H3 signature 58 75 1.5E-62
6 g8296.t1 PRINTS PR00622 Histone H3 signature 80 98 1.5E-62
8 g8296.t1 PRINTS PR00622 Histone H3 signature 98 114 1.5E-62
1 g8296.t1 Pfam PF00125 Core histone H2A/H2B/H3/H4 1 107 3.5E-36
13 g8296.t1 ProSitePatterns PS00322 Histone H3 signature 1. 15 21 -
12 g8296.t1 ProSitePatterns PS00959 Histone H3 signature 2. 67 75 -
14 g8296.t1 SMART SM00428 h35 34 113 7.9E-38
10 g8296.t1 SUPERFAMILY SSF47113 Histone-fold 2 107 2.12E-40

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0003677 DNA binding MF
GO:0046982 protein heterodimerization activity MF
GO:0000786 nucleosome CC

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values