Gene loci information

Transcript annotation

  • This transcript has been annotated as Dynactin subunit 2.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g8359 g8359.t4 TSS g8359.t4 30026556 30026556
chr_2 g8359 g8359.t4 isoform g8359.t4 30026640 30027967
chr_2 g8359 g8359.t4 exon g8359.t4.exon1 30026640 30026675
chr_2 g8359 g8359.t4 cds g8359.t4.CDS1 30026640 30026675
chr_2 g8359 g8359.t4 exon g8359.t4.exon2 30026738 30026943
chr_2 g8359 g8359.t4 cds g8359.t4.CDS2 30026738 30026943
chr_2 g8359 g8359.t4 exon g8359.t4.exon3 30027002 30027967
chr_2 g8359 g8359.t4 cds g8359.t4.CDS3 30027002 30027761
chr_2 g8359 g8359.t4 TTS g8359.t4 30028080 30028080

Sequences

>g8359.t4 Gene=g8359 Length=1208
ATGTTGGACCCAAAGTTTAAAAATCTTCCATTCTTGGCACAAGATGAGAAAGATGTATAT
GAAACTGATGATCAATTATCCAGTGAAACTGATTATTACGAAGAGGAAACTGAGAATGAA
TCAATTGATCGCTTAAAATTAAATGTGAATGATGCTTTTTCAAAATTCAAGGGAAAATAT
TTAATTGGAAATGTTGATTTCTCTGATAGCATAAGCAAGAGAAATTTTGGCTATAATGCT
GTCTCTGGAATCTATGAGATTGTTGGTGAAGGTGAGAAAGAAACACCCGTTCAAAAACTT
CAACGATTGCAATTTGAGATGAATGAATTGATGGAGGAAGTGACATCTCTTGAGAATGAT
AAGAGCATTTCAAAAGAAGAGCATGAAGCATACTTTAAAATGTCGAAAGTTGTGCAAAAT
TCTAAAAAGATTCTTGATAGCTTACACATTGAAGAAGCTTTAGGTGGCCAAAACGGTGGT
CAACCAGCTGAGAAAGCTGTTAAGAATCTAATTACTCAAGTTGATAGCTATAAAAAAGGT
GCACCAGAGATGTCTGCTGAATTAATTAAATTGAAAACGCAGAGTGATATCACTTTTTCC
ACTCGCATTGCTGAGATGGAACATAAGTTACACAAAATTGAACAAACTGTTGGTATGAAA
CCAGACAAGTTGTCTCGAATCAATAGTTCTTTAGATACTAAGAATCTCCTTGAAGCTGTT
CAACAATTATCAACGAGATCCGCTTTGATTCAACCGAGTCAATTGGATATTATCGAACAG
AGACTTACAATTTTATCATCGAAAATGGACCAATTTAAAGATAAAGCAATTGCTGCCGGA
ACTGACCGTGAACGTGAACAGAAAATTACTGAATTATATGATTTGGCAAAATCAACTGAA
CCAATAACGAAAATACTTCCTGATATGCTCGAACGAATGAAAACTTTGGAAGCACTCCAT
TCATATGGTAATTTTAGTAACATCAATATATTCATGACATGATTTTATTATTTCATATTT
TAGCTGCAAACTTTAGTAAATTATTTGCTGAGTTAGAAGCAACACAGAATATTATTTTGA
AGGGAATCGCTGGTAACAAGGAACTTTTGCAAGGTGTTCAAAAAGCCTTTGTTGAAAATG
ATGAAAATGCTAAGAAAGAACTAAAAAAATTAGAAGAGCGTGTCATCGCTATAACAAATA
AGAAGTAA

>g8359.t4 Gene=g8359 Length=333
MLDPKFKNLPFLAQDEKDVYETDDQLSSETDYYEEETENESIDRLKLNVNDAFSKFKGKY
LIGNVDFSDSISKRNFGYNAVSGIYEIVGEGEKETPVQKLQRLQFEMNELMEEVTSLEND
KSISKEEHEAYFKMSKVVQNSKKILDSLHIEEALGGQNGGQPAEKAVKNLITQVDSYKKG
APEMSAELIKLKTQSDITFSTRIAEMEHKLHKIEQTVGMKPDKLSRINSSLDTKNLLEAV
QQLSTRSALIQPSQLDIIEQRLTILSSKMDQFKDKAIAAGTDREREQKITELYDLAKSTE
PITKILPDMLERMKTLEALHSYGNFSNINIFMT

Protein features from InterProScan

Transcript Database ID Name Start End E.value
3 g8359.t4 Coils Coil Coil 100 127 -
4 g8359.t4 Coils Coil Coil 255 275 -
2 g8359.t4 PANTHER PTHR15346 DYNACTIN SUBUNIT 4 321 2.3E-55
1 g8359.t4 Pfam PF04912 Dynamitin 16 323 1.1E-72

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005869 dynactin complex CC
GO:0007017 microtubule-based process BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values