Gene loci information

Transcript annotation

  • This transcript has been annotated as Dynactin subunit 2.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g8359 g8359.t7 TSS g8359.t7 30026556 30026556
chr_2 g8359 g8359.t7 isoform g8359.t7 30026640 30027967
chr_2 g8359 g8359.t7 exon g8359.t7.exon1 30026640 30026943
chr_2 g8359 g8359.t7 exon g8359.t7.exon2 30027002 30027726
chr_2 g8359 g8359.t7 cds g8359.t7.CDS1 30027078 30027726
chr_2 g8359 g8359.t7 exon g8359.t7.exon3 30027783 30027967
chr_2 g8359 g8359.t7 cds g8359.t7.CDS2 30027783 30027967
chr_2 g8359 g8359.t7 TTS g8359.t7 30028080 30028080

Sequences

>g8359.t7 Gene=g8359 Length=1214
ATGTTGGACCCAAAGTTTAAAAATCTTCCATTCTTGGTAAGTTAAAGAATTATTTATAAT
GTACAATATTAAAGTGATAATTTGAAAAATACTTTAAGGCACAAGATGAGAAAGATGTAT
ATGAAACTGATGATCAATTATCCAGTGAAACTGATTATTACGAAGAGGAAACTGAGAATG
AATCAATTGATCGCTTAAAATTAAATGTGAATGATGCTTTTTCAAAATTCAAGGGAAAAT
ATTTAATTGGAAATGTTGATTTCTCTGATAGCATAAGCAAGAGAAATTTTGGCTATAATG
CTGTCTCTGGAATCTATGAGATTGTTGGTGAAGGTGAGAAAGAAACACCCGTTCAAAAAC
TTCAACGATTGCAATTTGAGATGAATGAATTGATGGAGGAAGTGACATCTCTTGAGAATG
ATAAGAGCATTTCAAAAGAAGAGCATGAAGCATACTTTAAAATGTCGAAAGTTGTGCAAA
ATTCTAAAAAGATTCTTGATAGCTTACACATTGAAGAAGCTTTAGGTGGCCAAAACGGTG
GTCAACCAGCTGAGAAAGCTGTTAAGAATCTAATTACTCAAGTTGATAGCTATAAAAAAG
GTGCACCAGAGATGTCTGCTGAATTAATTAAATTGAAAACGCAGAGTGATATCACTTTTT
CCACTCGCATTGCTGAGATGGAACATAAGTTACACAAAATTGAACAAACTGTTGGTATGA
AACCAGACAAGTTGTCTCGAATCAATAGTTCTTTAGATACTAAGAATCTCCTTGAAGCTG
TTCAACAATTATCAACGAGATCCGCTTTGATTCAACCGAGTCAATTGGATATTATCGAAC
AGAGACTTACAATTTTATCATCGAAAATGGACCAATTTAAAGATAAAGCAATTGCTGCCG
GAACTGACCGTGAACGTGAACAGAAAATTACTGAATTATATGATTTGGCAAAATCAACTG
AACCAATAACGAAAATACTTCCTGATATGCTCGAACGAATGAAAACTTTGGAAGCACTCC
ATTCATATGCTGCAAACTTTAGTAAATTATTTGCTGAGTTAGAAGCAACACAGAATATTA
TTTTGAAGGGAATCGCTGGTAACAAGGAACTTTTGCAAGGTGTTCAAAAAGCCTTTGTTG
AAAATGATGAAAATGCTAAGAAAGAACTAAAAAAATTAGAAGAGCGTGTCATCGCTATAA
CAAATAAGAAGTAA

>g8359.t7 Gene=g8359 Length=277
MNELMEEVTSLENDKSISKEEHEAYFKMSKVVQNSKKILDSLHIEEALGGQNGGQPAEKA
VKNLITQVDSYKKGAPEMSAELIKLKTQSDITFSTRIAEMEHKLHKIEQTVGMKPDKLSR
INSSLDTKNLLEAVQQLSTRSALIQPSQLDIIEQRLTILSSKMDQFKDKAIAAGTDRERE
QKITELYDLAKSTEPITKILPDMLERMKTLEALHSYAANFSKLFAELEATQNIILKGIAG
NKELLQGVQKAFVENDENAKKELKKLEERVIAITNKK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
4 g8359.t7 Coils Coil Coil 1 21 -
3 g8359.t7 Coils Coil Coil 149 169 -
5 g8359.t7 Coils Coil Coil 249 276 -
2 g8359.t7 PANTHER PTHR15346 DYNACTIN SUBUNIT 2 274 2.5E-37
1 g8359.t7 Pfam PF04912 Dynamitin 1 271 1.2E-55

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005869 dynactin complex CC
GO:0007017 microtubule-based process BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values