General information for g836.t15
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as MAP kinase-interacting serine/threonine-protein kinase 1.
Parent gene
- The parent gene g836 is located on chr_3: 6388313..6392170 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g836 | g836.t15 | TSS | g836.t15 | 6385279 | 6385279 |
| chr_3 | g836 | g836.t15 | isoform | g836.t15 | 6385362 | 6386333 |
| chr_3 | g836 | g836.t15 | exon | g836.t15.exon1 | 6385362 | 6385457 |
| chr_3 | g836 | g836.t15 | cds | g836.t15.CDS1 | 6385364 | 6385457 |
| chr_3 | g836 | g836.t15 | exon | g836.t15.exon2 | 6385831 | 6386333 |
| chr_3 | g836 | g836.t15 | cds | g836.t15.CDS2 | 6385831 | 6386333 |
| chr_3 | g836 | g836.t15 | TTS | g836.t15 | NA | NA |
Sequences
>g836.t15 Gene=g836 Length=599
TAAATTTTAATAAAGGAGCAGAAGTGATTGTGCGAAAGTCACAGCCAATTCGACGAAGAG
TACGACAACGAAGGCCATTGATAACAAATTTCTCTGAACTGTATAAATTGACGGGCGAAA
TATTGGGAGAAGGTGCCTATGCCTCAGTACAAACCTGTATAAATATATTCACCGATGTAG
AGTGTGCCGTTAAAATTATTGATAAGATACCAGGCCATGCACGAGCTCGAGTATTTCGTG
AAGTAGAGACGTTCCATCATTGTCAGGGACATCCGAATATTCTCCAATTAATTGAGTTCT
TTGAGGATAAGGAGAAATTCTATTTAGTATTTGAAAAGATCAATGGTGGTCCGCTATTGA
CGCGTATACAAGAGAACATTTGCTTCTCAGAGCATGATGCAGCACAAATAATTAAGGAAA
TAGCCTCAGGATTGAATTTTTTGCATAAGAAGGGCATAGCTCATCGTGATTTGAAACCTG
AAAATATTTTATGCGTTAATCCGGACACAATTTGTCCCATTAAAATATGTGATTTTGATC
TCGGCTCGGGAATTAATTTTACGACTGACGTTTCTGAATCAGTGGCCACTCCGCAACTT
>g836.t15 Gene=g836 Length=199
NFNKGAEVIVRKSQPIRRRVRQRRPLITNFSELYKLTGEILGEGAYASVQTCINIFTDVE
CAVKIIDKIPGHARARVFREVETFHHCQGHPNILQLIEFFEDKEKFYLVFEKINGGPLLT
RIQENICFSEHDAAQIIKEIASGLNFLHKKGIAHRDLKPENILCVNPDTICPIKICDFDL
GSGINFTTDVSESVATPQL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g836.t15 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 23 | 112 | 6.4E-34 |
| 9 | g836.t15 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 113 | 199 | 2.9E-20 |
| 2 | g836.t15 | PANTHER | PTHR24349 | SERINE/THREONINE-PROTEIN KINASE | 16 | 191 | 3.3E-72 |
| 3 | g836.t15 | PANTHER | PTHR24349:SF254 | MAP KINASE-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2 | 16 | 191 | 3.3E-72 |
| 1 | g836.t15 | Pfam | PF00069 | Protein kinase domain | 38 | 197 | 2.1E-40 |
| 7 | g836.t15 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 41 | 64 | - |
| 6 | g836.t15 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 152 | 164 | - |
| 10 | g836.t15 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 35 | 199 | 27.199 |
| 5 | g836.t15 | SMART | SM00220 | serkin_6 | 35 | 199 | 3.4E-17 |
| 4 | g836.t15 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 38 | 196 | 9.58E-45 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed