Gene loci information

Transcript annotation

  • This transcript has been annotated as UDP-glucose 6-dehydrogenase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g8464 g8464.t1 TTS g8464.t1 30844654 30844654
chr_2 g8464 g8464.t1 isoform g8464.t1 30844813 30847199
chr_2 g8464 g8464.t1 exon g8464.t1.exon1 30844813 30845215
chr_2 g8464 g8464.t1 cds g8464.t1.CDS1 30844813 30845215
chr_2 g8464 g8464.t1 exon g8464.t1.exon2 30845272 30845977
chr_2 g8464 g8464.t1 cds g8464.t1.CDS2 30845272 30845977
chr_2 g8464 g8464.t1 exon g8464.t1.exon3 30846046 30846214
chr_2 g8464 g8464.t1 cds g8464.t1.CDS3 30846046 30846214
chr_2 g8464 g8464.t1 exon g8464.t1.exon4 30846943 30847055
chr_2 g8464 g8464.t1 cds g8464.t1.CDS4 30846943 30847055
chr_2 g8464 g8464.t1 exon g8464.t1.exon5 30847112 30847199
chr_2 g8464 g8464.t1 cds g8464.t1.CDS5 30847112 30847199
chr_2 g8464 g8464.t1 TSS g8464.t1 30847468 30847468

Sequences

>g8464.t1 Gene=g8464 Length=1479
ATGATGGCGAATGGTGATTCTAATGGAACGACAATTCCTTCCTTTCCTATTTCTAAGATT
TGCTGTATTGGTGCCGGATATGTTGGCGGTCCAACATGTTCAGTAATGGCATTGATGTGT
CCTGATATAAAAGTCACGGTCGTTGATGTAAGCAAGGAAAGAATAAATCAATGGAATTCT
GAGAAATTGCCAATTTATGAGCCTGGCTTAGATGAAGTTGTAAGAAAATGCCGAGGAAGA
AATCTTTTCTTTTCAACTGACATGGAGAGTGCAATCAATGAAGCAGAGCTTATTTTCATT
TCTGTCAATACGCCAACAAAAGTGAATGGCAATGGTAAAGGTCGAGCAGCTGACTTGAAA
CATGTCGAAGGTTGCGCTCGATTGATAGCAAATATCGCACAGAGTAGTAAAATTGTCGTT
GAGAAAAGTACAGTGCCAGTGCGAGCAGCTGAAAGTATTATGCATGTATTGAAGGCCAAT
AATAAGCCAGGAGTAAAATATTCAATTCTTTCGAATCCTGAATTCCTTGCTGAAGGAACT
GCCATTGAAAATCTAATGAAACCTGATCGAGTTTTAATTGGAGGTGAAGAAACTTTAGAT
GGAAAAAAAGCGGTTGAAACCTTATGTTGGGTTTATGAGCATTGGGTATCAAAAGATAAA
ATTTTAACAACAAACACTTGGAGTTCAGAACTTTCAAAACTTGCTGCCAATGCAATGCTC
GCTCAACGAATTAGCAGTATTAATTCACTCTCAGCTGTTTGTGAAAGCACTGGTGCTGAT
GTATCAGAAGTTGCTCGTGCAATTGGCTTAGATTCAAGAATCGGCTCGAAATTTTTACAA
GCTTCAGTTGGATTCGGTGGAAGTTGCTTTCAAAAAGATCTTTTGAATTTGGTTTATATT
TGTGAGAAATTGAATCTACCAGAAGTTGCTCAATATTGGCAGAAAGTCATTGATATGAAT
GAATATCAAAAGGAAAGATTTGCACACAAAATTATTGAGTGTCTTTTCAATACTGTCAAT
GAAAAAAGAATTTCAGTTCTTGGATTTGCTTTTAAAAAGAACACTGGTGATACTCGTGAA
ACTCCAGCAATTTCTGTCTGCAAAGTTCTCCTTGATGAAGGCGCAAAATTAAATATTTAT
GATCCGAAAGTAGAGAAATCTCAAATTATTAATGACTTAACATCTCCACGTGTTACTGAT
TTTCCCGATGAGACGAGAAAATCAATTGAAATTTTCTCAGATCCATATGCAGCTGTGGAA
AACACACATGCGATTGTTATATGCACTGAATGGGATGAATTTGTTGAATTGGATTATAAT
CGAATCTTACAATCAATGATGAAGCCAGCTTACATTTTTGATGGTCGAAAAATATTGAAT
CATGAGGAGTTGCAGGATCTCGGCTTTCATGTCATTACAATTGGCAAAAAACTTAATAGA
ATTGGTTTTAGAACTTTTGGTAGTATTCCACAACAATGA

>g8464.t1 Gene=g8464 Length=492
MMANGDSNGTTIPSFPISKICCIGAGYVGGPTCSVMALMCPDIKVTVVDVSKERINQWNS
EKLPIYEPGLDEVVRKCRGRNLFFSTDMESAINEAELIFISVNTPTKVNGNGKGRAADLK
HVEGCARLIANIAQSSKIVVEKSTVPVRAAESIMHVLKANNKPGVKYSILSNPEFLAEGT
AIENLMKPDRVLIGGEETLDGKKAVETLCWVYEHWVSKDKILTTNTWSSELSKLAANAML
AQRISSINSLSAVCESTGADVSEVARAIGLDSRIGSKFLQASVGFGGSCFQKDLLNLVYI
CEKLNLPEVAQYWQKVIDMNEYQKERFAHKIIECLFNTVNEKRISVLGFAFKKNTGDTRE
TPAISVCKVLLDEGAKLNIYDPKVEKSQIINDLTSPRVTDFPDETRKSIEIFSDPYAAVE
NTHAIVICTEWDEFVELDYNRILQSMMKPAYIFDGRKILNHEELQDLGFHVITIGKKLNR
IGFRTFGSIPQQ

Protein features from InterProScan

Transcript Database ID Name Start End E.value
11 g8464.t1 Gene3D G3DSA:3.40.50.720 - 14 225 0
12 g8464.t1 Gene3D G3DSA:1.20.5.100 - 226 257 0
10 g8464.t1 Gene3D G3DSA:3.40.50.720 - 258 485 0
4 g8464.t1 PANTHER PTHR11374 UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE 17 484 0
5 g8464.t1 PANTHER PTHR11374:SF34 UDP-GLUCOSE 6-DEHYDROGENASE 17 484 0
14 g8464.t1 PIRSF PIRSF500133 UDPglc_DH_euk 13 487 0
15 g8464.t1 PIRSF PIRSF000124 UDPglc_GDPman_dh 18 476 0
2 g8464.t1 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 19 201 0
3 g8464.t1 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 227 321 0
1 g8464.t1 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 346 460 0
9 g8464.t1 SMART SM00984 UDPG_MGDP_dh_C_a_2_a 345 461 0
6 g8464.t1 SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains 19 218 0
7 g8464.t1 SUPERFAMILY SSF48179 6-phosphogluconate dehydrogenase C-terminal domain-like 227 326 0
8 g8464.t1 SUPERFAMILY SSF52413 UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 330 470 0
13 g8464.t1 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 19 457 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor MF
GO:0003979 UDP-glucose 6-dehydrogenase activity MF
GO:0051287 NAD binding MF
GO:0055114 NA NA

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values