Gene loci information

Transcript annotation

  • This transcript has been annotated as Fatty acid synthase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g8552 g8552.t1 isoform g8552.t1 31273908 31280799
chr_2 g8552 g8552.t1 exon g8552.t1.exon1 31273908 31274314
chr_2 g8552 g8552.t1 cds g8552.t1.CDS1 31273908 31274314
chr_2 g8552 g8552.t1 exon g8552.t1.exon2 31274367 31274758
chr_2 g8552 g8552.t1 cds g8552.t1.CDS2 31274367 31274758
chr_2 g8552 g8552.t1 exon g8552.t1.exon3 31274815 31275164
chr_2 g8552 g8552.t1 cds g8552.t1.CDS3 31274815 31275164
chr_2 g8552 g8552.t1 exon g8552.t1.exon4 31275663 31280061
chr_2 g8552 g8552.t1 cds g8552.t1.CDS4 31275663 31280061
chr_2 g8552 g8552.t1 exon g8552.t1.exon5 31280120 31280323
chr_2 g8552 g8552.t1 cds g8552.t1.CDS5 31280120 31280323
chr_2 g8552 g8552.t1 exon g8552.t1.exon6 31280384 31280799
chr_2 g8552 g8552.t1 cds g8552.t1.CDS6 31280384 31280799
chr_2 g8552 g8552.t1 TSS g8552.t1 NA NA
chr_2 g8552 g8552.t1 TTS g8552.t1 NA NA

Sequences

>g8552.t1 Gene=g8552 Length=6168
ATGAGTGAAAAAAGTGATGATGTGGTTATAAGTGGAATTGCTGGCCGATTTCCAAAATCT
CGAAATTTAAAAGAATTCAGTGAGAATTTATTTAAAAAAGTAGATATGACTGATGACAGT
GAAGTTCTTTGGAAACACATCCTTGAAAATATTCCTAAACGTAGTGGAAAAATTACTGAT
CTCGATAAATTCGATGCGAAATTTTTTTCCATGATGAATAATCAAGCAAATCTTACCGAT
CCACAATTAAGAATTTTATTTGAGCATGTTTATGAAGCAATTTTAGATGCAGGCATAAGT
CCTCAATCTTTAATTGAAAGTAATACTGGTGTCATTATTGGTTGTAGTATGTCAGAATCC
ATGTTTACTTATACAAAAGGATCATCCGTTGCTGAAAGTGGTGCCGCAACTTATAACAAT
GGACCATTCTTTCTTGCGAGTAAAATTTCTTATACTTTTGGTTTTCGTGGACCAGCACTT
ATTATTGATACAGCTTGCTCTAGTGCTGCAAGTGCATTGAATTGTGCTCTTAAATATATT
AAACAAAATGAGTGTGATGCTGCGATTGTAGCTGGCAGTCATCTTAATCTGGGTCCACGA
ATGTTTATAGAGTTTTCTGGCTTAGGTGCATTAACTCCAGATGGAATTTCTAAAGTTTTT
GATGAAGATTCAAAAGGTTTCGTTCGTTCAGATGCAATTGCTGCCGTATTTCTTCAAAAA
CGTAAAGATGCTAAGCGAATTTATGCCCAACTTGTTCATTCATTATCAAATAATGATGGA
TTCAAACATGAAGGAATACTTTTACCTTCAAAAGAAGTTCAACAGTTACTCATGGAAAGA
TTATATAAAGAAGTCAATATTGACCCAAGTGAAATTAATTATTTTGAGGCTCATGCAACT
GGAACTAAACTTGGAGATTTTCAGGAAATTGGAGCAGTTGATGAAGTTTTTTGCAAGAAA
AATCGTCAAAATAATTTAATTGTTGGTAGTGTTAAATCAAATTTGGGCCATGCTGAAGCT
GCTAGTGCAATGCCTTCTTTGGCAAAAATTTTGATAGCTTTTGAAAGTGGAAAAATTCCA
CCAAATATAAATTTGAATAAACTTCGCGAAGATATTCCAGCTTTTGCAGAAGGAAGAATC
GAAGTTGCAACAGATGCTGTACCATTAACATCGGAATATATTTCAATGAATAGCTTCGGT
TTTGGTGGTTATAATGTTCATCTTTTATTTAAAAGAAATTCAAAGCAAAAAATTATTACA
AATATTGGCAATATTGAGCGAATGGTTTTATGGTCAGGAAGAACAGAAGATGCTGTTCAT
GCAATTTTTGATGATATCATAAGTCGTCCACTTGATATCGAATATATTGCATTACTTCAA
AACACTCAAACTATCACACCAAATTTAAATTGTTATCGAGGTTTTGGAATTTTCAAAAAT
AACGAAGAAAACACAATTTGTATTGAACGAAATGTTCAAAGTTTCGATGGTATTCGTCGT
CAAATTGTTTTTTCATATGCTGGTATGGGATCACAATGGCATAAAATGGGACAAGATTTA
ATGGCAATTGAATTGTTTACTGAATCAATTGAAAAATGTCATGAAATTTTACTTGAAAAT
CAAATTAATTTGAAATCAATTTTAAATTCAAATGATGAAAAAATTTATGAAAATGTCTTG
AATGCTTATGTTGGAATTATTTCTATACAAATAGCTCTAACTGATGTTTTGTATGCTCTT
AATGTTAAACCAGATTGGATTGTTGGTCATTCAGTTGGAGAAATAGCTTGTGCTTATGCA
GATGGATGTTTGACAATGAAAGAAGCTTTAAATATTGCATATTTGAGAGCTAAACTCACT
CTTGATCTTAACATAAATGGCGGAGCAATGGCAGTTGTTGGAATGAGTAGTGAAGAACTG
GAGAAGATTTTGTCATATGATATTGATATTGCTTGTTATAATGCAAAAGAATTGATAACA
ATCAGTGGGAATAAGAAAGTCATTTCTGAATTTGTTGATCAATTAAAATCACAAAATATT
TTTGCAAAAGAAATTGAATGTGCTGGAGTTCCATTCCATAGTCGACATATGACTGTTATG
GCAAAAAAATTTGAAGAAAAATTACAAGATCTTTTAAAGACACCAAAAATGCGATCTAAC
AAATGGATAACAAGCACTTATAATGAAGAAAATGAGCAGAATAAAATTTGTAACATAAAA
TATCAAACTGACAACGTTACAAATTCTGTTTACTTTGATAAAGCTATTGAAAATCTTCCT
AAAAATTCTTTGATTATTGAAATTTCCCCTCATGGTTTACTTAAAACATTCTTTAAATTA
TCTTCGAATGAAAGTATTTATGAAAGATTAATGAATAAAAATTCGAAAAATCATAAAGAT
TTCTTTATGCAATCTCTCGGAAAAATATTTCAACATGGAGTTGATTTGGATATAAGTAAA
TTGTATCCAGCTATTAAATTTCCAGTTTCTCGAGGTACTTCAATGATTTCACCATTAATC
AAATGGAATCATGAGCATAATTATTTTGTGCCAATGTTCGATCATGATTTTGAATTTAGT
CGTTTTTCAAAAATATTCAACTTTAATTCTCCAGAATATTCTTATGTTTATGATCACGTT
ATTGATGGAAAAGCAATAATTCCTGCTATGTTTTGGATACACTCTATTTGGAAATATTTT
GCAGCATTTTGTGAAAGAAAATGGTACGAAACTAAAATAACACTAACAAAAGTTGAATGT
GTTCAATTAGCTTATCCAGATAAGGAAGTAAAAATAACTTTATTGATGAATAGAAAAACT
GGAAATGTTGAAATTTATTGTGGTAACAATCTAATTATGAAAGCCATTGCAAAATGTGAT
GATAATGTGCAAATTGATGAAATTGAAGATTCCAAATATTCAGATGATGACGTTGTATTA
ACTAAAGACGATTTTTATAAATTTGTTCATATTCATGGTTATCATTATAAAGAAGGATTT
CAATTAGTTCATGAAATAACTAACACTGGATTAAAAGGCAAAATTAAATGGAACAACAAT
TGGGCAACTTTTGCTGATACACTTTTTCAAATGTTACTAATTAAAATGACTTCATTAAAT
CAAATTGGATTGCCGAGAAAAATTGAGAAAATTTCTTTTGATCCAATTCTTCATAATAAA
ATTCTTGAACGAGCAAAATTGAATAATAAACAAAACAATCAGTCAGAAATTCTTTTACCT
ATTGAAGGACGTTATGATTTAGGCACAATAAGATGTGGTGGTGTTGAAATGTATGAACCT
TTACCAATTGCTATTAACAGACAAGAACAAAAAAATTTAACTCATGAATTTTATAAATTT
ATTTCATTTGAAAATGATGAACGAAAATTTGAATTTTCGGATGCTTTAAAGATTTTTTCT
ACGACTATAATTGACAGAAATCCCAAACAAACATACAATCTAATAGAAATAAATGATGAA
AGTTCTGATTTTTGGGCTCCTATGCTTGAAATCAACAGTCGGTCAATGCAAAATGTTTTA
AATATTAAAGTCTTAACAAAAACAGACCAAAAAATCAATAATGTAGAAGTTATTACTGAT
AAAGATATTTCAATATTCAACAATATTGACGCTATTTATGCCAGATATAAATTGAATGAA
TTTGAATTCATAAATAAAATTTCAAAAGTGTTGTGTAAAGATGGCATTTTAATAACACTT
GAAGAATCAAAAGTTGAAAAATGTAATGAAAAAATTGAAATTTTATCAAAATTGACTTTA
AAAAGTAATCAGAGTTTAATTATGGCAAGAATGAAAACAGAAGAAATTCTATTGAAACCA
GTGATATTCAAAATTACTTCAAATTTGCCAGAATGGTTCGAAAATTTGAAACAAAATATT
TTAAATTTTTCGAAAAATTCTAATCAGACAGTTTTGCTTTATTCACAAGAACCATATGTT
GGACTTCTTGGATTTTATAATTGTTTACGTTTAGAATTTCCAGAAATCAATATTTCATGT
TTCATTATTGATGACACAAATGCACCAGAATTTGACATTGAAAATTCGTTTTATAAGAAA
CAATTTTTGAGAGGTTTTAAAAAGAACATTTTGAAAAATAATCAATGGGGAACGTTTTAT
CATCTGAATATGAATATAACATGTGAACCTGTGTCATATAAAGAGCAATGCTTTGCAAAT
TATAGCAGAAGAGGCAATCTTAATACTATTAAGTGGCATCAAGGACCAATGACTGTTTTG
GATAATCCACAAAACAATTGTGATTTGATTAAAGTACAATATGTTGCACTTAATTTTAAA
GACATTGTTTATGCTTTTGGTTACATACCTGATGGAGTAAATCTCATAAAAGAATGTTCA
TTAGGACTAGAATTTGGAGGTATTCGAGTTAAAACTGGTGAAAGAGTTTTTGTACTAACA
AGAAATACTGCTGGAATAACTTCTTACTTTGATACAAGTGATAAAGAAAATACAATTGTT
AAAAAAATTGATGATGAATTAGAACTAATTGATATGACTTCATCATTACTTGTTTATTTT
ACTGTTTATTATTCATTTTTTTATACAACAAAAATAGAAAAAGGTAAATCAATTTTGATT
CATAGTGGAGCAGGTGGCGTTGGTCAGGCAGCTCTTCATACTGCATTTAATAACGATTTG
GAAGTTTTTGTCACTGTCGGGACTGAAGAAAAGAGAAAATTTTTACTTGAAAATTTTTCT
AAATTGAAGCCTGAAAATATTGGAAATTCTCGTGACACATCCTTTTACAAAATGGTTATG
ACACAAACTAATGGGCGAGGTGTTGACTATGTTTTGAATTCTCTAAGTGGTGATAAAATG
ATTGCATCATTAGATTGTGTTGCAAAAAATGGATGTTTTTTGGAAATTGGTCAAGCTGAT
ATAATGTTGGGAACACAAATCAGTTTGAAATTTTTGGAAAGAAATATTTCAATAAAATCA
GTTAGAGCAGATTTGATAGATTTTTCAATAATACCTGAAAAAATTTTTTCTGATATCCTT
GAAGATTTTAAAAAAGGAAAAATTAAACCGCCAAGCAGAACTGTTTTTGATGCAAATGAT
GTTGTTAAAGCATTCCAACATATGTCTACTGGTAATCATATCGGTAAAATAATATTGAAG
ATTCGTGAGAATTTGAATGATGAAGAAACTTTGCCTATTTCTGTGACGCCTCGTTTCTAT
TGCAATCCTGAGCGATCTTACATAATTGTTGGCGGACTTAATGGACTTGGCTTTGAATTT
TCTGAATGGCTTGTTGGACGAAAATGTCGTAAAATTATTTTTAACTCAAGAAGAGGCATA
ACTAATCAATATCAGATTTTCAAAATAAATTATTGGAAATCTTTTGGTGTGGAAGTTATT
GTCAACACATCTGATGCCACAACTGAAGCAGGATGTAAAGAATTAATCAAAATAGCGAAT
GACCATGGTGTTGTTGATGGAATTTTCAATTTTGCTGCAATTATCAAAGATGGATTTTTT
TCAAATCAGACATTAGAAGCTTTCAATCAAACTCTTGCTCCAAAAGCAATTATAACCAAA
TATCTACATGAATTATCACTTAAACTTTGTCCACAATTGAAACATTTTATCGTTTATTCA
AGTGTTTCTTGTGGTATTGGAATGCCTGGACAAACAAATTATGGAATGGCAAACTCTATA
ATGGAAGAAATCATACTTAAACGATATGAAATGGGACTTCCAGCAAAAGCATTGCAGTGG
GGAGCAATTGCGGATGTTGGTATCCTCGCAAATATGGGAAATGCAGAAGGAACTAAATAT
AATTTTAAATTTTCGGTTCAGTCTCTTGCTTCTTTCTTAGAATGTCATGATCTTCTTTTA
TTACATCCAGAACCAATTGTTACTTGTGCAACCTTTAATCAACATAAAAGCTTAAAAGAA
GGCAAACAAAGATTTACTGAAGTCTTGATGGATTTTTTTAACATTGAAGATCGTTCATCT
TTCTCTTTGAACTCAACATTCTCTCAGCTTGGCGTAGATTCATTAGGTGGAATAGAAATA
CAAAATATGATAGAAAGAGAATTTGGTGTTAGTTTTACAGTCCAAGAACTAAGGAGTATG
ACATTAGGAGAAATTGATGAAAAAATTGAAAAGAAAAGAAATGATTAA

>g8552.t1 Gene=g8552 Length=2055
MSEKSDDVVISGIAGRFPKSRNLKEFSENLFKKVDMTDDSEVLWKHILENIPKRSGKITD
LDKFDAKFFSMMNNQANLTDPQLRILFEHVYEAILDAGISPQSLIESNTGVIIGCSMSES
MFTYTKGSSVAESGAATYNNGPFFLASKISYTFGFRGPALIIDTACSSAASALNCALKYI
KQNECDAAIVAGSHLNLGPRMFIEFSGLGALTPDGISKVFDEDSKGFVRSDAIAAVFLQK
RKDAKRIYAQLVHSLSNNDGFKHEGILLPSKEVQQLLMERLYKEVNIDPSEINYFEAHAT
GTKLGDFQEIGAVDEVFCKKNRQNNLIVGSVKSNLGHAEAASAMPSLAKILIAFESGKIP
PNINLNKLREDIPAFAEGRIEVATDAVPLTSEYISMNSFGFGGYNVHLLFKRNSKQKIIT
NIGNIERMVLWSGRTEDAVHAIFDDIISRPLDIEYIALLQNTQTITPNLNCYRGFGIFKN
NEENTICIERNVQSFDGIRRQIVFSYAGMGSQWHKMGQDLMAIELFTESIEKCHEILLEN
QINLKSILNSNDEKIYENVLNAYVGIISIQIALTDVLYALNVKPDWIVGHSVGEIACAYA
DGCLTMKEALNIAYLRAKLTLDLNINGGAMAVVGMSSEELEKILSYDIDIACYNAKELIT
ISGNKKVISEFVDQLKSQNIFAKEIECAGVPFHSRHMTVMAKKFEEKLQDLLKTPKMRSN
KWITSTYNEENEQNKICNIKYQTDNVTNSVYFDKAIENLPKNSLIIEISPHGLLKTFFKL
SSNESIYERLMNKNSKNHKDFFMQSLGKIFQHGVDLDISKLYPAIKFPVSRGTSMISPLI
KWNHEHNYFVPMFDHDFEFSRFSKIFNFNSPEYSYVYDHVIDGKAIIPAMFWIHSIWKYF
AAFCERKWYETKITLTKVECVQLAYPDKEVKITLLMNRKTGNVEIYCGNNLIMKAIAKCD
DNVQIDEIEDSKYSDDDVVLTKDDFYKFVHIHGYHYKEGFQLVHEITNTGLKGKIKWNNN
WATFADTLFQMLLIKMTSLNQIGLPRKIEKISFDPILHNKILERAKLNNKQNNQSEILLP
IEGRYDLGTIRCGGVEMYEPLPIAINRQEQKNLTHEFYKFISFENDERKFEFSDALKIFS
TTIIDRNPKQTYNLIEINDESSDFWAPMLEINSRSMQNVLNIKVLTKTDQKINNVEVITD
KDISIFNNIDAIYARYKLNEFEFINKISKVLCKDGILITLEESKVEKCNEKIEILSKLTL
KSNQSLIMARMKTEEILLKPVIFKITSNLPEWFENLKQNILNFSKNSNQTVLLYSQEPYV
GLLGFYNCLRLEFPEINISCFIIDDTNAPEFDIENSFYKKQFLRGFKKNILKNNQWGTFY
HLNMNITCEPVSYKEQCFANYSRRGNLNTIKWHQGPMTVLDNPQNNCDLIKVQYVALNFK
DIVYAFGYIPDGVNLIKECSLGLEFGGIRVKTGERVFVLTRNTAGITSYFDTSDKENTIV
KKIDDELELIDMTSSLLVYFTVYYSFFYTTKIEKGKSILIHSGAGGVGQAALHTAFNNDL
EVFVTVGTEEKRKFLLENFSKLKPENIGNSRDTSFYKMVMTQTNGRGVDYVLNSLSGDKM
IASLDCVAKNGCFLEIGQADIMLGTQISLKFLERNISIKSVRADLIDFSIIPEKIFSDIL
EDFKKGKIKPPSRTVFDANDVVKAFQHMSTGNHIGKIILKIRENLNDEETLPISVTPRFY
CNPERSYIIVGGLNGLGFEFSEWLVGRKCRKIIFNSRRGITNQYQIFKINYWKSFGVEVI
VNTSDATTEAGCKELIKIANDHGVVDGIFNFAAIIKDGFFSNQTLEAFNQTLAPKAIITK
YLHELSLKLCPQLKHFIVYSSVSCGIGMPGQTNYGMANSIMEEIILKRYEMGLPAKALQW
GAIADVGILANMGNAEGTKYNFKFSVQSLASFLECHDLLLLHPEPIVTCATFNQHKSLKE
GKQRFTEVLMDFFNIEDRSSFSLNSTFSQLGVDSLGGIEIQNMIEREFGVSFTVQELRSM
TLGEIDEKIEKKRND

Protein features from InterProScan

Transcript Database ID Name Start End E.value
26 g8552.t1 CDD cd00833 PKS 6 409 3.62097E-134
27 g8552.t1 CDD cd05195 enoyl_red 1430 1719 7.1677E-85
25 g8552.t1 Coils Coil Coil 2042 2055 -
21 g8552.t1 Gene3D G3DSA:3.40.47.10 - 5 412 4.0E-125
19 g8552.t1 Gene3D G3DSA:3.30.70.3290 - 426 849 1.5E-143
24 g8552.t1 Gene3D G3DSA:3.40.366.10 - 498 813 1.5E-143
20 g8552.t1 Gene3D G3DSA:3.10.129.110 - 863 1111 3.8E-37
18 g8552.t1 Gene3D G3DSA:3.40.50.720 - 1291 1969 1.3E-200
23 g8552.t1 Gene3D G3DSA:3.90.180.10 - 1386 1739 1.3E-200
22 g8552.t1 Gene3D G3DSA:1.10.1200.10 - 1978 2055 3.7E-13
9 g8552.t1 PANTHER PTHR43775 FATTY ACID SYNTHASE 4 2052 0.0
10 g8552.t1 PANTHER PTHR43775:SF23 FATTY ACID SYNTHASE 3 4 2052 0.0
4 g8552.t1 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 244 6.7E-55
1 g8552.t1 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 248 365 4.8E-33
8 g8552.t1 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 370 477 9.8E-24
6 g8552.t1 Pfam PF00698 Acyl transferase domain 503 803 5.0E-54
3 g8552.t1 Pfam PF14765 Polyketide synthase dehydratase 872 1055 9.5E-7
7 g8552.t1 Pfam PF13602 Zinc-binding dehydrogenase 1591 1719 2.6E-14
2 g8552.t1 Pfam PF08659 KR domain 1746 1924 3.9E-36
5 g8552.t1 Pfam PF00550 Phosphopantetheine attachment site 1987 2044 1.4E-8
28 g8552.t1 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 157 173 -
34 g8552.t1 ProSiteProfiles PS50075 Carrier protein (CP) domain profile. 1979 2055 10.335
32 g8552.t1 SMART SM00825 Beta-ketoacyl synthase 8 413 3.8E-86
30 g8552.t1 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 505 795 7.6E-22
29 g8552.t1 SMART SM00829 PKS_ER_names_mod 1405 1719 1.0E-81
33 g8552.t1 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1745 1926 1.6E-13
31 g8552.t1 SMART SM00823 Phosphopantetheine attachment site 1982 2037 0.004
12 g8552.t1 SUPERFAMILY SSF53901 Thiolase-like 5 411 3.27E-60
11 g8552.t1 SUPERFAMILY SSF52151 FabD/lysophospholipase-like 502 779 3.66E-39
17 g8552.t1 SUPERFAMILY SSF55048 Probable ACP-binding domain of malonyl-CoA ACP transacylase 626 683 3.01E-7
15 g8552.t1 SUPERFAMILY SSF50129 GroES-like 1421 1541 9.95E-8
14 g8552.t1 SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains 1514 1661 9.87E-29
13 g8552.t1 SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains 1744 1966 9.49E-27
16 g8552.t1 SUPERFAMILY SSF47336 ACP-like 1983 2050 3.66E-9

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0031177 phosphopantetheine binding MF
GO:0016746 acyltransferase activity MF
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity MF
GO:0016740 transferase activity MF
GO:0006633 fatty acid biosynthetic process BP
GO:0016491 oxidoreductase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed