Gene loci information

Transcript annotation

  • This transcript has been annotated as Nucleoside diphosphate kinase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g8645 g8645.t2 TTS g8645.t2 32079417 32079417
chr_2 g8645 g8645.t2 isoform g8645.t2 32079427 32080578
chr_2 g8645 g8645.t2 exon g8645.t2.exon1 32079427 32079532
chr_2 g8645 g8645.t2 cds g8645.t2.CDS1 32079477 32079532
chr_2 g8645 g8645.t2 exon g8645.t2.exon2 32079668 32079865
chr_2 g8645 g8645.t2 cds g8645.t2.CDS2 32079668 32079865
chr_2 g8645 g8645.t2 exon g8645.t2.exon3 32079947 32080031
chr_2 g8645 g8645.t2 cds g8645.t2.CDS3 32079947 32080031
chr_2 g8645 g8645.t2 exon g8645.t2.exon4 32080110 32080578
chr_2 g8645 g8645.t2 cds g8645.t2.CDS4 32080110 32080235
chr_2 g8645 g8645.t2 TSS g8645.t2 NA NA

Sequences

>g8645.t2 Gene=g8645 Length=858
ATGTCTAAATTGTTAGTTTCATTAACTAAAAATTATAATTCAATTCGGACGGCTCAAGTA
AAATTGTTTTGCAAGCGACGGCGACCTCTCGACGATTCAAGTAATTTTTTTTATTCTCAA
TTGAGTTATTCGCCGAAGAAGAGGTATGTCAATAAGACTTAATTTATTTTTTTTCCTAAA
CTTGCATAATTTAGTTGATTAGAATCTAATGCATTTACAGTTTGATTGCTTTTCTAATAC
TCGCAAGCTGTGTTCACACATTTTTAGTATATTATTTATATTTCTCTGCTTCAGTCTAAA
TTTCACTTGCGATCTTGAAAACGAAAAAAGCAGAAGTAACAACATGGCAAATAATGAAAG
AACTTTTATCATGTGCAAGCCTGATGCCGTTCAACGCGGAATTGTTGGAGAAATAATCAA
ACGCTTCGAAACAAAAGGTTTCAAACTCGTTGGAATGAAATTTATGTGGGCATCCAAAGA
TCTTTTGGAGAAACATTATGCCGATTTAAGCTCACGTCCCTTCTTCCCAGGTCTTGTTAA
TTACATGTCATCAGGTCCTGTTGTTCCAATGGTTTGGGAAGGATTAAATGCAGTCAAAAC
AGGCAGAGTTATGTTGGGAGCAACTAATCCAGCTGATTCAGCACCTGGAACAATCAGAGG
AGATTTGTGCGTTCAAGTTGGTCGTAATATAATCCACGGCTCTGACTCTGTTGAGAGTGC
AAAGAAAGAAATCGCATTGTGGTTCAATGTAAATATCAATATACAACCGATTGTCTCACA
TACACACATATTCCAGTTATTCAATTGATATTTCTGCATTTGTAATTAAAAGTTCATGAA
AGTGAAAAATATAAAAAA

>g8645.t2 Gene=g8645 Length=154
MANNERTFIMCKPDAVQRGIVGEIIKRFETKGFKLVGMKFMWASKDLLEKHYADLSSRPF
FPGLVNYMSSGPVVPMVWEGLNAVKTGRVMLGATNPADSAPGTIRGDLCVQVGRNIIHGS
DSVESAKKEIALWFNVNINIQPIVSHTHIFQLFN

Protein features from InterProScan

Transcript Database ID Name Start End E.value
15 g8645.t2 CDD cd04413 NDPk_I 5 134 9.25174E-95
14 g8645.t2 Coils Coil Coil 149 154 -
13 g8645.t2 Gene3D G3DSA:3.30.70.141 - 1 149 2.3E-63
6 g8645.t2 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 4 140 32.987537
3 g8645.t2 PANTHER PTHR11349 NUCLEOSIDE DIPHOSPHATE KINASE 1 64 1.2E-76
5 g8645.t2 PANTHER PTHR11349:SF103 NUCLEOSIDE DIPHOSPHATE KINASE 1 64 1.2E-76
2 g8645.t2 PANTHER PTHR11349 NUCLEOSIDE DIPHOSPHATE KINASE 63 135 1.2E-76
4 g8645.t2 PANTHER PTHR11349:SF103 NUCLEOSIDE DIPHOSPHATE KINASE 63 135 1.2E-76
7 g8645.t2 PRINTS PR01243 Nucleoside diphosphate kinase signature 7 29 9.5E-56
11 g8645.t2 PRINTS PR01243 Nucleoside diphosphate kinase signature 51 70 9.5E-56
8 g8645.t2 PRINTS PR01243 Nucleoside diphosphate kinase signature 71 88 9.5E-56
10 g8645.t2 PRINTS PR01243 Nucleoside diphosphate kinase signature 92 108 9.5E-56
9 g8645.t2 PRINTS PR01243 Nucleoside diphosphate kinase signature 115 134 9.5E-56
1 g8645.t2 Pfam PF00334 Nucleoside diphosphate kinase 5 135 1.7E-53
17 g8645.t2 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 115 123 -
16 g8645.t2 SMART SM00562 ndk_5 4 140 4.4E-83
12 g8645.t2 SUPERFAMILY SSF54919 Nucleoside diphosphate kinase, NDK 3 136 2.23E-59

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006228 UTP biosynthetic process BP
GO:0006241 CTP biosynthetic process BP
GO:0006165 nucleoside diphosphate phosphorylation BP
GO:0004550 nucleoside diphosphate kinase activity MF
GO:0006183 GTP biosynthetic process BP

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values