Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Protein max.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g8669 g8669.t2 TTS g8669.t2 32168821 32168821
chr_2 g8669 g8669.t2 isoform g8669.t2 32169222 32170065
chr_2 g8669 g8669.t2 exon g8669.t2.exon1 32169222 32169512
chr_2 g8669 g8669.t2 cds g8669.t2.CDS1 32169222 32169512
chr_2 g8669 g8669.t2 exon g8669.t2.exon2 32169585 32169650
chr_2 g8669 g8669.t2 cds g8669.t2.CDS2 32169585 32169650
chr_2 g8669 g8669.t2 exon g8669.t2.exon3 32169716 32169763
chr_2 g8669 g8669.t2 cds g8669.t2.CDS3 32169716 32169763
chr_2 g8669 g8669.t2 exon g8669.t2.exon4 32169843 32169899
chr_2 g8669 g8669.t2 cds g8669.t2.CDS4 32169843 32169899
chr_2 g8669 g8669.t2 exon g8669.t2.exon5 32170000 32170065
chr_2 g8669 g8669.t2 cds g8669.t2.CDS5 32170000 32170065
chr_2 g8669 g8669.t2 TSS g8669.t2 32170144 32170144

Sequences

>g8669.t2 Gene=g8669 Length=528
ATGAAATATTACGAAGAAAACAGTGCTGCGATGAGTGAAGATGAGAATCTTGATGTCGAA
AGTGACGAAGAAGAATCAAGCGATAATAAATCCCGAAATGCAAACAATCAATATTTCTCG
CAAGCTGAAAAGCGTGCACATCACAATGCTCTGGAGAGAAAAAGAAGAGATCACATAAAA
GATAGTTTCACATCTTTACGTGATTCTGTTCCTTCACTTCAAGGCGAGAAGGTACATGCA
AGTCGTGCACAGATACTAAAGAAAGCGGCCGAATATATACAATTTATGCGACGCAAAAAC
AATTCACATCAACAGGACATTGATGATTTAAAACGTCAAAATTCAATGCTTGAAGCGCAA
ATTCGATCACTTGAGCGAGCAAGACAAACTGGAAATTTTGGTGGTGGTGAGAGTGGAAAC
GAAGTTGCAATGGAAAGTGTTAAATCAGACGTAAGCTCGCATGAGAGTTCAGATGAAAAT
GACGAAAATGAACGCAGAAATAAGCGTTTTAAGACAACTACTTATTAA

>g8669.t2 Gene=g8669 Length=175
MKYYEENSAAMSEDENLDVESDEEESSDNKSRNANNQYFSQAEKRAHHNALERKRRDHIK
DSFTSLRDSVPSLQGEKVHASRAQILKKAAEYIQFMRRKNNSHQQDIDDLKRQNSMLEAQ
IRSLERARQTGNFGGGESGNEVAMESVKSDVSSHESSDENDENERRNKRFKTTTY

Protein features from InterProScan

Transcript Database ID Name Start End E.value
9 g8669.t2 CDD cd11406 bHLHzip_Max 44 114 2.24201E-40
8 g8669.t2 Coils Coil Coil 93 130 -
7 g8669.t2 Gene3D G3DSA:4.10.280.10 HLH 44 124 8.9E-30
14 g8669.t2 MobiDBLite mobidb-lite consensus disorder prediction 1 79 -
11 g8669.t2 MobiDBLite mobidb-lite consensus disorder prediction 45 64 -
12 g8669.t2 MobiDBLite mobidb-lite consensus disorder prediction 127 175 -
13 g8669.t2 MobiDBLite mobidb-lite consensus disorder prediction 151 175 -
2 g8669.t2 PANTHER PTHR10328 PROTEIN MAX MYC-ASSOCIATED FACTOR X 13 166 9.0E-45
4 g8669.t2 PRINTS PR00044 Myc proto-oncogene signature 36 52 1.7E-8
5 g8669.t2 PRINTS PR00044 Myc proto-oncogene signature 53 68 1.7E-8
3 g8669.t2 PRINTS PR00044 Myc proto-oncogene signature 79 92 1.7E-8
1 g8669.t2 Pfam PF00010 Helix-loop-helix DNA-binding domain 44 96 1.3E-15
15 g8669.t2 ProSiteProfiles PS50888 Myc-type, basic helix-loop-helix (bHLH) domain profile. 43 96 15.529
10 g8669.t2 SMART SM00353 finulus 49 102 1.6E-14
6 g8669.t2 SUPERFAMILY SSF47459 HLH, helix-loop-helix DNA-binding domain 42 123 2.13E-18

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0090575 RNA polymerase II transcription regulator complex CC
GO:0071339 MLL1 complex CC
GO:0006355 regulation of transcription, DNA-templated BP
GO:0003700 DNA-binding transcription factor activity MF
GO:0046983 protein dimerization activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values