Gene loci information

Transcript annotation

  • This transcript has been annotated as Rapamycin-insensitive companion of mTOR.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g8877 g8877.t1 TSS g8877.t1 33618712 33618712
chr_2 g8877 g8877.t1 isoform g8877.t1 33618773 33624884
chr_2 g8877 g8877.t1 exon g8877.t1.exon1 33618773 33618957
chr_2 g8877 g8877.t1 cds g8877.t1.CDS1 33618773 33618957
chr_2 g8877 g8877.t1 exon g8877.t1.exon2 33619093 33620935
chr_2 g8877 g8877.t1 cds g8877.t1.CDS2 33619093 33620935
chr_2 g8877 g8877.t1 exon g8877.t1.exon3 33621061 33622338
chr_2 g8877 g8877.t1 cds g8877.t1.CDS3 33621061 33622338
chr_2 g8877 g8877.t1 exon g8877.t1.exon4 33622394 33622649
chr_2 g8877 g8877.t1 cds g8877.t1.CDS4 33622394 33622649
chr_2 g8877 g8877.t1 exon g8877.t1.exon5 33622708 33622984
chr_2 g8877 g8877.t1 cds g8877.t1.CDS5 33622708 33622984
chr_2 g8877 g8877.t1 exon g8877.t1.exon6 33623052 33623128
chr_2 g8877 g8877.t1 cds g8877.t1.CDS6 33623052 33623128
chr_2 g8877 g8877.t1 exon g8877.t1.exon7 33623191 33624884
chr_2 g8877 g8877.t1 cds g8877.t1.CDS7 33623191 33624884
chr_2 g8877 g8877.t1 TTS g8877.t1 33625524 33625524

Sequences

>g8877.t1 Gene=g8877 Length=5610
ATGAAGTCGATTAATAATAATACCTATTACGAGTTAAACAACTCGAGTAGCATAATAGAA
ATTTTTAATTTAATTTCAAATCAAAATACAAATGAGAAAAAGCGACTTACAGCGCTAAAT
AATTGCACGAAATTATTGTCAAACAGTACCAGTAATATTTTTACTACAGAGGAGCTTCTT
TATTGCCTAAGTTCCAACTATGTTTCGAATATCACACAAATTCGTGCTGGCGCTTTACGT
TTATCACGCTATATATTGAATACAGTACATGACCTACAAACTTTCAATAAACTACAACTT
CCCATACTTTTATGCAGAAGCTTGGATTTAGTTGTTAAGAATGAAGAAGAAAGAATACAG
GCATTGAAATTAATAAGAAAGATGATAGCAATTCAGCCTGATTTATTAAATCCAGCAATT
GTAAGATGTCTCACATCATTAGGTGACACGCTAATGATTGATGGCACAAAGCCGGATCGA
ATAGTACGTGCGTGTTTGGCCACTCTCTCGGAATTGGGTGTTTTAAATCCAGTTTTATTA
ATTTTAACAAACGGTGTGGCAGTAATAACTCGCAATGTACTCGAATGTGACAGTCCTCGC
ATTGCAGAAAGTTTAGTTGGTGTGTTATTGCACTTGTTAGAATATCCGCACACACGAAAT
ATTGCGGGCATTCGACTGGATTGTCTCGCTGCACCTTATTGCGATTTCACTTACCGCTTA
GGAATTATGGACAAAAATAAGGACGCACGAGAATTACGATTCAAATGTTCACGTTTAGCA
CTTCTTTCAGTGCTTCGGAGTTTTAATGGAGTTTTAGAATTTTGCAATCCTAATAAGGCA
TCGGGTTTGAAAGCCATTATTGATGTATTATATTTGAATCAATTAGAAGTTAGAAAAGCC
ATTTTGGATTTATTGTATGAGCTCATAAACCTTCCGCAAGCAGTTTGGACGGACGAATAT
TCAGTGGCGTTAGCCGCAGTCGATCCCTCAGACTATCAAGATTCGTGGCGTTTGAGCGAG
GGATTTGTGGCGCTAGAAGGACGTTCAGTTTTGCCAAGTTTGATCAACAAAGTGCCCAAT
ATATGTGAAATACATCAGGCCTTTATTCTCTATTGTTTTCTTGAGAATGGCCTGCTCAAT
GCCTTAGTCGAAGTAATAATAAGTAGCGACACTTTTATATCCGTTCGAGCGACAATTTTA
TTGGCTAAACTACTACAAATGATTCACACAATGTTACCGGCCGATGTCTGTAGTACATCA
CCACCACTTCCGATGCTGATTGCGAAAGCCACTGAAGGAAATTATCAAGCAAGAGCTGCC
ATTTCAGCATTGCAAGCATATCACACAATGATAAAAAATCGACCTGCTGCTTGCAGTTTA
TATCTTGATTGTATTATTCAGAATGGCGAACTTATTAAATCGAGGCTGTTTAAACGAGAA
ATCGATGCTGTCGAGAGTCTTTCTAAATCTGCTAGTCTTACATTTTTTGAACGAATGCGA
CACGATTCTATTGGTTCTACCGATGCTAGTGCAAGTTTTTATTTTGACATTTTTCGAGAT
ACTACTAGCATGAGCGGTGAGACTGAAACGAGTAAATCATTTGAAAAATCGAAAGGAGCA
ACGCTTGTACGAAGAAAAATTATTGGATTTCTAGAGAAATTTCGAGAGAATGAACGATTA
ATAAAAGATTCATTAGTATTGACACATGTTGATGCAAATACATGGGACTGGGATATTGTG
GTGACAATTTTTCGCAATAAAACACTCAGTGCAAAGCCAGACGAGGATCAGTTGAAATTC
ATTAAGAATCTAACGAATTATTTTAAACCGAGTAGTAATAAATTCTCACATATGGAACTT
AGTGTTAACAGCAACTGTCGAATGATTCCATCAAACGTTCATGCTGGAATTATGCTCATT
GATTATCTTCTCGAGCAAATTGATGAACTGGAGTATATGAGAGTTTTGACTGACTACTGC
TCAGATATATCAACACAATTACAGGCAATTTATAAGAAGAAAGCGCATGATTGCTTATTT
TCACCCTCTCATATGAATACAACAATGTGCCAGCAATATTTCCTTTTTATTGGACGATTG
TGTCGATCGAAGAAGGGCATTGATATATTAAAAAATACAGACATTTTAAAGCATTTAACG
TATCTTGTAGCGAATACAAATCATACGATATATGTAAAATTGATTGTTTCCGGTCTCGAT
TATTCTTCGGCGCAACCTCATCCACGTTTGATTCTTGAAAAAGCTTTAACTTCGTCTCCA
AATCAGGCATCACGTTTATATGCAACACAATTTTTATTAGTTTTACTACGCGCACGTCTA
CCAACATTTGAAGAATGGGGAATTCAAATAATTATGAATCAGCTTAAGGATAAAGATAGA
GCGGTAGTATTGGCTGCATTAGAAATTATAGAGGAAGCATGTCACGAGAATATTTACTTA
TTAGAATTGGCACACGTCTGGCCAGAATTAGATAAATATCATGAAGTGGGAAAGTACACA
ATGATGCGATTTTATTCCATTCCTCGTGGACTCAATCATCCTAATGCAAATGTCAAAGCA
GAAATTGATTTGTGGATAAGTGTATATAATAAGAAATACGTTTTATTTGTTGAATCTGAG
ACACATTCGACAATGACACTTCATACGAAAAGTGAAGATGGATATTACATGAGTCGCAAC
TCTTTCCAACAACGACAGATGGTAAAGACAACAAATTTACCATGTCATCTTTATGGTGCT
CTCGTACAAACACAACGTGGAATAAGCTACTTACAAAAACATGGTAATATCTCTTATTTA
ATAGACGTATTGAGTTCAGCAAAATGTGGGAATGAGGACGAATGCTTGCTGCTTAAATCT
GCATTATGGGCAATCGGTCACGTTGCAACCAACCATGATGGCATTGAATTTCTTAATAAT
ACTGTGACACGAGTATTTGAGAAAGTTATTCAATTGATAAAATACTGTGAAATCTATTCA
ATTCGTGCATGTGCATTCAATGTTTTGTGTTTGATGAGTACAACTGTTAATGGATCAAAT
TTATTATATAAACTTGATTGGATGAGTGTGCGACACGATCGAAATAATGAATTTCCAATT
CTGGAACCAGAAGATTGGCATCTCAAAAATCCTTCGCCTGCTCGTTACAATCATGACATG
CCCGCATATATGCCGGCATATAATTATGGAGGAATTGATGATAGCATAATGTTGAATCTC
AGTGGTACTCAGCAACAACCGTCATTGGTCATTGAAGAATCAATTGATTCAATAAAAGAA
GATGATAATCGTGATGAGTCATTAAATATGACAACATCAACACAAAAATCAAAAACACTT
CCAGTTGGAACATTACCATCACAAATGCATCAAAAGAATGTCAAACATATAAGATCATTA
TCAGAATCAAAAACTACTGATGGAATTACGGGTTTAGCATCAACTACTACTACAACTAAT
CGTACTCGCTTTAATTCAGGAGATTCAAATACTTCTGGTGTTAGTAGTTGTGATTCTATT
AATATAAAAGCTGACAAAAGGAATGAACGATTTCGAAGAGTCTCATTAACAGGGACACCA
ATTAAGGATGTAAGTCAACTTTCAAATCAAGACATTCATGGCTATAAAAAATTAAGAATG
ATACGAAGAAATATGCGTCCAATGCTGAGTGAATCAGCAGCTGACGATATATTGGCAGAT
ATATTCGAAAATGATGGAAATGGAGGAAAAACTTCAAATCGATTATTGCAATCATTTAAT
CTAGACTCGAAGCGAAAGCAGAGTAAAAATTTAGAGAGGCAAACAATAAACATCTCAGGG
TTTGATGATATTCAAAAGAATATTTATGTGGCCAAATTGTTAACGCAAATTGATACCAAA
GGTCCTTGTTATAGAGGAATTTGTCTTCCAAGGAATATACTTGATTTATTTCCGGATAGT
CACAGTCAAAGTGGAACAACATATGTTTCACGTTACATTCAGGAAATAGAAACACTCGAA
TCGAATAATTTATCAACATCATCAATATTATTAAAGAATCAATATCCAAATGAGGGCGAT
GCTGCTGGTGATTTAATTGCTGGTCAAGTGCCTGATGAATCGGCAGTATCGAGTATGTCT
GATTTATCAACAACGGGTAATAGAAGAATGAGAAAGAGACCGATAATTTTGTCAGGAGTG
ACAAGTGCAATGACTGCTACAGCAACAGATACGGCTACAATTGAAAGTGACATGCCGGTA
ACAATGATTCGATCAATGAGTTCAACCGGTGGCACAATTAAGCACAACAAAGATGAATGT
CTACTATGTTGTCGAAGTAAAGTTATAAGTAGAGTAATAGACACATCGTTAAACATTCAA
GAGCCTAAAGAAAATCTTACATCAATGAATGGAAAAATTCGCGATTCAGATGTATCATTT
TATTCGCCTGAGAGCATCGTAAGTGATGATTCTGCAAACACAAATATGCCGGATCGTATT
TCAAATATTATACTGAGAAATTTTCAAAAAATGGCAAATCCAATCATGTTCAAAACATGT
CGAAAAATTCTCATGGAATTAAAACAAAAGTATCCACAATCATTTCAAGACATTTGTCTT
TATTCGGAAGTTTGTAAATTTATGGGCTCATGTAATTATCGAATGACTGTGAGGCGGTTT
ATTCAGGAAATTTTCTTGGATTTAAATTACGATGCTTTCAATACAGATGTTGATTTAATT
TTAAATGCAGCACGACAACGTCTTACAGATTTGAAACTTTTGGATACGTCAAAGACATTT
CCTTCATCACCCCCTCAATCGAGTAGCAATGTGCAAGTTTTAAATGTTCACATACCGAGT
CATTCTTCATCATCACTGCCCGCTTCATCTCCAACCTCATCAACTCATTCACAGCATTCA
GCTACTGGCATAACTATAAGCATCACTTCAACAACTACAAGTATCACAACACATAAGCTT
CATTCACTCAAATCACCACTGCTCGCAAGCGTTCATGAGAGTAGTGTTGAAAATCTAATA
GTGGATTCACCTAAAGAATCAATTCAAACCAAAGATGAAGTGGATTCGAGTGTTGTTATA
TTAAGAACGACCGAAAAGAAAACTTTGTCATCACCTGGAAGCTCACAAAAAGTAAAGGCC
GAAATTCATGATTATCGTCATAGTATAGATGCAAGTAGTGAGTCATCATCATCAATGCAA
CCGATACGCAGACGACGCTTTAATACATTAGAACTAGATTTAAGTTGTACGAGAAACAAA
TTTCCAATAAAACATCGCTCACAGCCATCAGCAACATCAACACTTCAGCGACGACCGATT
TCAAGTTCAAGTGCCAACAGCAACAATAATAAGGAAGATGTTGAACAACAATCAACGATA
ACAAAAAAATTCTCAACCAGTGATCATAGTTTTGAATCAACACAAAGCATAAGTTTAACC
TCACCAATTTCACCGCCACCTCTCGGTCCCTTATATTGTGAACAAAGATTACTTCAATCT
GATTTTCATAAATCGGAGGCTACCCTTAGTAATAATAACAGAAACATTAATCTTAATATT
GATAAAACTAATGATAAGCAGAAAAAATAA

>g8877.t1 Gene=g8877 Length=1869
MKSINNNTYYELNNSSSIIEIFNLISNQNTNEKKRLTALNNCTKLLSNSTSNIFTTEELL
YCLSSNYVSNITQIRAGALRLSRYILNTVHDLQTFNKLQLPILLCRSLDLVVKNEEERIQ
ALKLIRKMIAIQPDLLNPAIVRCLTSLGDTLMIDGTKPDRIVRACLATLSELGVLNPVLL
ILTNGVAVITRNVLECDSPRIAESLVGVLLHLLEYPHTRNIAGIRLDCLAAPYCDFTYRL
GIMDKNKDARELRFKCSRLALLSVLRSFNGVLEFCNPNKASGLKAIIDVLYLNQLEVRKA
ILDLLYELINLPQAVWTDEYSVALAAVDPSDYQDSWRLSEGFVALEGRSVLPSLINKVPN
ICEIHQAFILYCFLENGLLNALVEVIISSDTFISVRATILLAKLLQMIHTMLPADVCSTS
PPLPMLIAKATEGNYQARAAISALQAYHTMIKNRPAACSLYLDCIIQNGELIKSRLFKRE
IDAVESLSKSASLTFFERMRHDSIGSTDASASFYFDIFRDTTSMSGETETSKSFEKSKGA
TLVRRKIIGFLEKFRENERLIKDSLVLTHVDANTWDWDIVVTIFRNKTLSAKPDEDQLKF
IKNLTNYFKPSSNKFSHMELSVNSNCRMIPSNVHAGIMLIDYLLEQIDELEYMRVLTDYC
SDISTQLQAIYKKKAHDCLFSPSHMNTTMCQQYFLFIGRLCRSKKGIDILKNTDILKHLT
YLVANTNHTIYVKLIVSGLDYSSAQPHPRLILEKALTSSPNQASRLYATQFLLVLLRARL
PTFEEWGIQIIMNQLKDKDRAVVLAALEIIEEACHENIYLLELAHVWPELDKYHEVGKYT
MMRFYSIPRGLNHPNANVKAEIDLWISVYNKKYVLFVESETHSTMTLHTKSEDGYYMSRN
SFQQRQMVKTTNLPCHLYGALVQTQRGISYLQKHGNISYLIDVLSSAKCGNEDECLLLKS
ALWAIGHVATNHDGIEFLNNTVTRVFEKVIQLIKYCEIYSIRACAFNVLCLMSTTVNGSN
LLYKLDWMSVRHDRNNEFPILEPEDWHLKNPSPARYNHDMPAYMPAYNYGGIDDSIMLNL
SGTQQQPSLVIEESIDSIKEDDNRDESLNMTTSTQKSKTLPVGTLPSQMHQKNVKHIRSL
SESKTTDGITGLASTTTTTNRTRFNSGDSNTSGVSSCDSINIKADKRNERFRRVSLTGTP
IKDVSQLSNQDIHGYKKLRMIRRNMRPMLSESAADDILADIFENDGNGGKTSNRLLQSFN
LDSKRKQSKNLERQTINISGFDDIQKNIYVAKLLTQIDTKGPCYRGICLPRNILDLFPDS
HSQSGTTYVSRYIQEIETLESNNLSTSSILLKNQYPNEGDAAGDLIAGQVPDESAVSSMS
DLSTTGNRRMRKRPIILSGVTSAMTATATDTATIESDMPVTMIRSMSSTGGTIKHNKDEC
LLCCRSKVISRVIDTSLNIQEPKENLTSMNGKIRDSDVSFYSPESIVSDDSANTNMPDRI
SNIILRNFQKMANPIMFKTCRKILMELKQKYPQSFQDICLYSEVCKFMGSCNYRMTVRRF
IQEIFLDLNYDAFNTDVDLILNAARQRLTDLKLLDTSKTFPSSPPQSSSNVQVLNVHIPS
HSSSSLPASSPTSSTHSQHSATGITISITSTTTSITTHKLHSLKSPLLASVHESSVENLI
VDSPKESIQTKDEVDSSVVILRTTEKKTLSSPGSSQKVKAEIHDYRHSIDASSESSSSMQ
PIRRRRFNTLELDLSCTRNKFPIKHRSQPSATSTLQRRPISSSSANSNNNKEDVEQQSTI
TKKFSTSDHSFESTQSISLTSPISPPPLGPLYCEQRLLQSDFHKSEATLSNNNRNINLNI
DKTNDKQKK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
13 g8877.t1 MobiDBLite mobidb-lite consensus disorder prediction 1102 1121 -
15 g8877.t1 MobiDBLite mobidb-lite consensus disorder prediction 1622 1641 -
12 g8877.t1 MobiDBLite mobidb-lite consensus disorder prediction 1760 1808 -
14 g8877.t1 MobiDBLite mobidb-lite consensus disorder prediction 1761 1808 -
5 g8877.t1 PANTHER PTHR13298 CYTOSOLIC REGULATOR PIANISSIMO 15 1571 2.8E-285
3 g8877.t1 Pfam PF14664 Rapamycin-insensitive companion of mTOR, N-term 38 413 5.4E-84
1 g8877.t1 Pfam PF14666 Rapamycin-insensitive companion of mTOR, middle domain 673 776 2.5E-28
4 g8877.t1 Pfam PF14663 Rapamycin-insensitive companion of mTOR RasGEF_N domain 783 886 1.7E-24
2 g8877.t1 Pfam PF14668 Rapamycin-insensitive companion of mTOR, domain 5 958 1027 1.7E-19
8 g8877.t1 SMART SM01308 RICTOR_N_3 36 413 6.2E-121
9 g8877.t1 SMART SM01307 RICTOR_M_2 552 778 1.8E-63
10 g8877.t1 SMART SM01303 RasGEF_N_2_2 779 891 4.5E-29
11 g8877.t1 SMART SM01310 RICTOR_V_2 955 1029 3.0E-24
6 g8877.t1 SUPERFAMILY SSF48371 ARM repeat 24 459 6.2E-9
7 g8877.t1 SUPERFAMILY SSF48371 ARM repeat 285 1023 1.15E-10

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0031929 TOR signaling BP
GO:0031932 TORC2 complex CC

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values