Gene loci information

Transcript annotation

  • This transcript has been annotated as Arginine kinase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g8960 g8960.t26 TSS g8960.t26 34206336 34206336
chr_2 g8960 g8960.t26 isoform g8960.t26 34206429 34214613
chr_2 g8960 g8960.t26 exon g8960.t26.exon1 34206429 34206585
chr_2 g8960 g8960.t26 exon g8960.t26.exon2 34213006 34213280
chr_2 g8960 g8960.t26 cds g8960.t26.CDS1 34213019 34213280
chr_2 g8960 g8960.t26 exon g8960.t26.exon3 34213336 34213874
chr_2 g8960 g8960.t26 cds g8960.t26.CDS2 34213336 34213874
chr_2 g8960 g8960.t26 exon g8960.t26.exon4 34213936 34214157
chr_2 g8960 g8960.t26 cds g8960.t26.CDS3 34213936 34214157
chr_2 g8960 g8960.t26 exon g8960.t26.exon5 34214230 34214613
chr_2 g8960 g8960.t26 cds g8960.t26.CDS4 34214230 34214277
chr_2 g8960 g8960.t26 TTS g8960.t26 34214625 34214625

Sequences

>g8960.t26 Gene=g8960 Length=1577
AGTGGGTAATAGAACGATGAATAGAAGCAGTACGATCATTATAAAATCTAGTTAAAAATA
TTTTCATATTTTTAAAACCAAAGAAAAATGTGTAGATATAAAAATTTAGGTCTAAAAGAA
TTTCCACTTTTCCCGATTTTCATTTATTACCGGTTACTAACAAATCCGAAATGGTTGACG
CTGCAGTACTTGAGAAATTGGAATCAGGCTTTGCCAAGCTCCAAGCCTCTGACTCGAAAT
CATTGCTTAAAAAGTATTTGACCAAGGAAGTCTTTGATAATCTTAAGAACAAGAAGACCC
CAACATTTGGTTCAACTTTGCTTGATGTCATCCAATCTGGTTTAGAAAACCACGACTCTG
GCGTCGGAATTTACGCACCAGATGCCGAGGCTTACACAACTTTCGCTGAATTGTTTGACC
CAATCATTGAAGACTACCATGGTGGATTCAAGAAGACCGACAAGCATCCAGCAAAGGACT
TTGGTGATGTAAATGCATTTGGAGATTTGGATCCAACTGGTGAATTCGTTGTCTCAACTC
GTGTCCGTTGCGGTCGCTCAATGGAAGGATATCCATTCAATCCATGCTTGACTGAAGCAC
AATACAAAGAAATGGAACAAAAGGTTTCAACCACATTGTCAGGCTTGGAAGGTGAATTGA
AGGGCAAATTCTACCCATTGACTGGCATGGACAAAGCTACTCAACAACAACTCATCGATG
ACCATTTCTTGTTCAAAGAAGGTGATCGCTTCTTGCAAGCTGCCAATGCTTGCCGCTATT
GGCCATCAGGTCGCGGTATCTACCACAATGATGCCAAGACTTTCCTTGTCTGGTGCAATG
AAGAAGATCACTTGCGTATCATTTCAATGCAAATGGGTGGCAATCTTGGTGAAGTTTTCC
GTCGTTTGACAACTGCCGTTAATGACATTGAGAAGCGTATTCCATTCAGCCACAACGACC
GCTTGGGATTCCTCACATTCTGCCCAACCAACTTGGGAACAACCATCCGTGCATCAGTTC
ACATTAAGGTTCCAAAATTGGCTGCCAACAAAGCTCGTCTTGAGGAAGTTGCTTCCAAAT
ACAATTTGCAAGTTCGTGGCACACGCGGAGAACATACAGAGGCTGAAGGTGGCATTTATG
ATATTTCAAACAAGAGACGTATGGGCTTGACTGAATTCCAAGCTGTCAAGGAGATGTACG
ATGGAATTACTGAAATCATCAAGATTGAAAAGTCATTGTAAAGTGTGTAAAAGCAAAAAC
AAAACAACCCAACTTAAAATTGTCATCTATTTTCAAAATTATACATTAATATAAAAAACA
CATATACACACATGAATTAACAACAAAACTCAATCGTCATTTGCAATGGCGATCAAAGAT
TTGGAAATCTTTCATCAGTGATCTTTATTCTTGTTTAATTTAATTGATAAAAAAATGTGT
CCTATTCTCTCCATCTCAGTATAAGTTTGATGTGATTGATCACAAGCATTAAGAATATTT
TGGAATAAAATGTGAATTTAACATCTATTACCACATACAGCACATGCAAACAAGAAGTTA
ATTAAATAAAAACCGTA

>g8960.t26 Gene=g8960 Length=356
MVDAAVLEKLESGFAKLQASDSKSLLKKYLTKEVFDNLKNKKTPTFGSTLLDVIQSGLEN
HDSGVGIYAPDAEAYTTFAELFDPIIEDYHGGFKKTDKHPAKDFGDVNAFGDLDPTGEFV
VSTRVRCGRSMEGYPFNPCLTEAQYKEMEQKVSTTLSGLEGELKGKFYPLTGMDKATQQQ
LIDDHFLFKEGDRFLQAANACRYWPSGRGIYHNDAKTFLVWCNEEDHLRIISMQMGGNLG
EVFRRLTTAVNDIEKRIPFSHNDRLGFLTFCPTNLGTTIRASVHIKVPKLAANKARLEEV
ASKYNLQVRGTRGEHTEAEGGIYDISNKRRMGLTEFQAVKEMYDGITEIIKIEKSL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
12 g8960.t26 CDD cd07932 arginine_kinase_like 9 356 0.0
9 g8960.t26 Gene3D G3DSA:1.10.135.10 Transferase Creatine Kinase 1 95 2.7E-38
8 g8960.t26 Gene3D G3DSA:3.30.590.10 Glutamine synthetase/guanido kinase 98 356 2.9E-120
3 g8960.t26 PANTHER PTHR11547:SF38 ARGININE KINASE-RELATED 8 355 7.5E-154
4 g8960.t26 PANTHER PTHR11547 ARGININE OR CREATINE KINASE 8 355 7.5E-154
1 g8960.t26 Pfam PF02807 ATP:guanido phosphotransferase, N-terminal domain 20 87 7.1E-30
2 g8960.t26 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 147 355 2.1E-86
7 g8960.t26 ProSitePatterns PS00112 Phosphagen kinase active site signature. 271 277 -
11 g8960.t26 ProSiteProfiles PS51509 Phosphagen kinase N-terminal domain profile. 6 91 26.463
10 g8960.t26 ProSiteProfiles PS51510 Phosphagen kinase C-terminal domain profile. 119 356 88.499
5 g8960.t26 SUPERFAMILY SSF48034 Guanido kinase N-terminal domain 18 100 3.14E-33
6 g8960.t26 SUPERFAMILY SSF55931 Glutamine synthetase/guanido kinase 97 355 5.33E-105

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0046314 phosphocreatine biosynthetic process BP
GO:0016301 kinase activity MF
GO:0004111 creatine kinase activity MF
GO:0003824 catalytic activity MF
GO:0016772 transferase activity, transferring phosphorus-containing groups MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values