Gene loci information

Transcript annotation

  • This transcript has been annotated as Cytosol aminopeptidase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g9024 g9024.t1 TTS g9024.t1 34706498 34706498
chr_2 g9024 g9024.t1 isoform g9024.t1 34706684 34708823
chr_2 g9024 g9024.t1 exon g9024.t1.exon1 34706684 34707061
chr_2 g9024 g9024.t1 cds g9024.t1.CDS1 34706684 34707061
chr_2 g9024 g9024.t1 exon g9024.t1.exon2 34707188 34707233
chr_2 g9024 g9024.t1 cds g9024.t1.CDS2 34707188 34707233
chr_2 g9024 g9024.t1 exon g9024.t1.exon3 34707298 34708022
chr_2 g9024 g9024.t1 cds g9024.t1.CDS3 34707298 34708022
chr_2 g9024 g9024.t1 exon g9024.t1.exon4 34708260 34708449
chr_2 g9024 g9024.t1 cds g9024.t1.CDS4 34708260 34708449
chr_2 g9024 g9024.t1 exon g9024.t1.exon5 34708572 34708708
chr_2 g9024 g9024.t1 cds g9024.t1.CDS5 34708572 34708708
chr_2 g9024 g9024.t1 exon g9024.t1.exon6 34708812 34708823
chr_2 g9024 g9024.t1 cds g9024.t1.CDS6 34708812 34708823
chr_2 g9024 g9024.t1 TSS g9024.t1 34708859 34708859

Sequences

>g9024.t1 Gene=g9024 Length=1488
ATGAGCAATTCGAAAGCCTTAGTGGTTGGTGTATATGTGAAAAGTTCTAAAGGAGAAGAA
AGTAGCGGAAAGAAAGAGATTGAGTTGTCGGCTTGTGCCAAGAAATTAAATGAAAAATCA
AATGGTGAACTTTTAAAGGCGATTAATTCCGCATATTGTGATAAACTATCAGCGGGAAAG
GCGAGATTGTTGTATGGCGTTAAAGATGTTGAAAATTATGGAGCTATTGCTGTTACCGCA
TTAGACTCTTCAAAATGGGATCGATTAGATGGACTTAACACAGAAAATGAATCGGTTCGA
ATTGCTGCATCGAGTGGAGTGAAAGCATTACAGTCTCTTAAAATCAACGACATTTATGTG
GATGATTTGGGATCAGCAAAAGCAGCTGCCGAAGGTAGTATATTGGCAAATTTCAAATTT
CAACCATACAAATCAAAAAAGAGTGAGCTTCCAAATATTCATGCTGTTGAGAAAAATGAT
GAATGGAATAAAGGTGCCATTTTTGCAAATGCTCAAAATTTTTGCAAAACTCTTATGGAT
ACTCCCGCAAATCTTATGACACCAACAATATTTTGTGAAACGGTTAAGGAAAAATTTGCT
GGCCTTGCCAATGTTAATATACAAGTTCATGATACAGAATGGATAAAAAAAGAAAAAATG
GGATTATTCCTGTCAGTAACAAGTGGCTCATCAGAACCACCAAAATTCTTGGAAATCACA
TATACAGGAGATTCATCATCATCACAAGACGTAATTGCACTTGTCGGAAAAGGCATCACA
TTTGACTCAGGCGGTATTAGTCTTAAACCCTCATCAAAAATGGATCAAATGAGAGGTGAT
ATGGGCGGTGCTGCTAATGTAGTTAGCACTATTTGGGCATTGGCATCACTTAAAGTACCG
GTTAATGTAAAAGGTTTTACACCACTTTGTGAAAATATGCCTGGTAATCGTGCCACAAAA
CCAGGTGATGTTATCTTTGGTCGCAACGGAAAAAGTGTTTGTATAGATAACACTGACGCT
GAGGGTCGACTTATATTGGCTGATGCTTTGAGTTATGCTTCTGACTTCAAGCCACGCTTT
ATCTTAGATATTGCAACATTAACTGGAGCGGCTCGTGTCGCACTTGGTGATTGTGTTACA
GCCATTTTTTCAAATTCTGATCCATTATGGGAATCAATTCAAGCTGCTGGCTCTGAAACT
GGAGATCGTGTTTGGAGAATGCCATTATATACACACTATTCCAATCAAATGACAGAACAT
GATGCATACGATTTGAATAATTTAGGAAAAGGCAAAGGTGGTGGTTCATGCACAGCAGCT
GCATTCCTTCGTGAATTTGTGCCTAAAAACTTATCATGGCTTCATGCTGACATTGCTGGT
GTTATGTGTGAGACATCTGATCAAAGTTATGTGGGAAATGGTGCTGCTATGACTGGACGT
CCTGTTAGAACACTTATTGAATTTGTTATACGTGAATCAAAAAAATGA

>g9024.t1 Gene=g9024 Length=495
MSNSKALVVGVYVKSSKGEESSGKKEIELSACAKKLNEKSNGELLKAINSAYCDKLSAGK
ARLLYGVKDVENYGAIAVTALDSSKWDRLDGLNTENESVRIAASSGVKALQSLKINDIYV
DDLGSAKAAAEGSILANFKFQPYKSKKSELPNIHAVEKNDEWNKGAIFANAQNFCKTLMD
TPANLMTPTIFCETVKEKFAGLANVNIQVHDTEWIKKEKMGLFLSVTSGSSEPPKFLEIT
YTGDSSSSQDVIALVGKGITFDSGGISLKPSSKMDQMRGDMGGAANVVSTIWALASLKVP
VNVKGFTPLCENMPGNRATKPGDVIFGRNGKSVCIDNTDAEGRLILADALSYASDFKPRF
ILDIATLTGAARVALGDCVTAIFSNSDPLWESIQAAGSETGDRVWRMPLYTHYSNQMTEH
DAYDLNNLGKGKGGGSCTAAAFLREFVPKNLSWLHADIAGVMCETSDQSYVGNGAAMTGR
PVRTLIEFVIRESKK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
15 g9024.t1 CDD cd00433 Peptidase_M17 4 489 0.0
14 g9024.t1 Gene3D G3DSA:3.40.220.10 Leucine Aminopeptidase 4 173 1.1E-36
13 g9024.t1 Gene3D G3DSA:3.40.630.10 Zn peptidases 174 492 4.0E-128
5 g9024.t1 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 494 29.962543
3 g9024.t1 PANTHER PTHR11963 LEUCINE AMINOPEPTIDASE-RELATED 7 492 5.8E-165
4 g9024.t1 PANTHER PTHR11963:SF40 CYTOSOL AMINOPEPTIDASE 7 492 5.8E-165
10 g9024.t1 PRINTS PR00481 Cytosol aminopeptidase signature 252 269 5.6E-48
6 g9024.t1 PRINTS PR00481 Cytosol aminopeptidase signature 274 295 5.6E-48
7 g9024.t1 PRINTS PR00481 Cytosol aminopeptidase signature 311 332 5.6E-48
8 g9024.t1 PRINTS PR00481 Cytosol aminopeptidase signature 333 353 5.6E-48
9 g9024.t1 PRINTS PR00481 Cytosol aminopeptidase signature 361 376 5.6E-48
1 g9024.t1 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 8 147 3.3E-10
2 g9024.t1 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 173 486 1.3E-118
16 g9024.t1 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 337 344 -
11 g9024.t1 SUPERFAMILY SSF52949 Macro domain-like 5 164 2.47E-20
12 g9024.t1 SUPERFAMILY SSF53187 Zn-dependent exopeptidases 169 490 4.71E-114

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006508 proteolysis BP
GO:0019538 protein metabolic process BP
GO:0005737 cytoplasm CC
GO:0070006 metalloaminopeptidase activity MF
GO:0030145 manganese ion binding MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values