Gene loci information

Transcript annotation

  • This transcript has been annotated as Importin-5.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g9158 g9158.t6 TTS g9158.t6 533366 533366
chr_1 g9158 g9158.t6 isoform g9158.t6 533932 536308
chr_1 g9158 g9158.t6 exon g9158.t6.exon1 533932 535685
chr_1 g9158 g9158.t6 cds g9158.t6.CDS1 533934 535685
chr_1 g9158 g9158.t6 exon g9158.t6.exon2 535748 535897
chr_1 g9158 g9158.t6 cds g9158.t6.CDS2 535748 535897
chr_1 g9158 g9158.t6 exon g9158.t6.exon3 536228 536308
chr_1 g9158 g9158.t6 cds g9158.t6.CDS3 536228 536308
chr_1 g9158 g9158.t6 TSS g9158.t6 536365 536365

Sequences

>g9158.t6 Gene=g9158 Length=1985
ATGGCCGAAGAAGACACACGATTTTCAAGTTTACTCACTTCCTTGCTCTCGATAGAAAAC
GATGAAAGAACTGCGGCAGAGGAAGCATACAATAATTTGGCTACAGAAGTAAAAGTCACA
TTATTACTGCGAGCTCTACAAAATGGACAAGTTTCAGAGGATGGAAGTTTGATGGCGGCT
GTTCTTTTAAGACGAGTCTTTTCATCAGATTTCCAGAACTTCTTTCCTAAATTAACGCCA
GAACAACAAGCCGAATTGAAACAACAAATTCTTTTGCTGCTACAAAAAGATGTTAGTCCA
AATTTAAGAAGAAAAATTTGTGAAGTTGTGGCAGAAGTGACTCGTAATTTTATTGACGAT
GATGGAAACAATCAATGGCCTGAAACACTTCAGCTTCTCTTTCAATGTGCAAACACTCCG
AATGCAATTTTGCAGGAATCAGCATTGCGCATTTTCGCATCTGTGCCAGGAATATTTGGC
AATCAACAAAATCATTATTTGCAAGTCATAAAAGAAATGTTGATGAAATATTTAGATCCA
TCCTCCACTCCAGAAGTTCGTTTTCAGGCAGTTCGTGCTGTTATTGCATTCATTCTTTTA
AATGACAAAGAAGTTGAAATTCAAAAAGCATTATCAGATTTGCTTCCACAAATAATCATG
ATTACAGCAGATTCAATCAAAGCTGAAGAAGATCAGACACTCATCAAATTACTTATTGAC
ATGTCTGAAAATGTACCAAAATTTTTGAGACCACAATTAGAGGCAATTTTTGAAATGTGC
ATTAATGTTTTTAAAAGTGAAGATGTTGAAGATTCATGGAGACATTTGGCATTAGAAGTT
ATGGTTTCATTGTCAGAAAATGCATCAGCAATGGTAAGAAAGAAAGCTGAAAAGTATATT
GCTGCATTAGTTCCACTCGTTCTTAAAATGATGACCGAATTAGAAGACGATGAAGAATGG
TCTGTGTCAGATGAAATTGAAGATGACGATACTGGAGAGAATAATGTTATAGCTGAATCA
GCACTTGATCGTTTGGCGTGTGGTTTAGGAGGTAAAGCCATTCTTCCTCACATTGTTTCA
AACATTCCAACTATGCTAAACAATCCCGATTGGAGATATCGTCATGCTGCTCTCATGGCA
ATCAGTGCTGCTGGCGAAGGATGTCATAAACAAATGGAAGCAATGTTGGATAGTGTCACT
GAAGGAACATTGAAATATTTGGCAGATCCTCATCCTCGTGTTCGATATGCTGCTTGTAAT
GCAATTGGTCAAATGGCAACAGATTTTGCTCCAGTTTTCGAAAAAAAGTTCCATGCTCAT
GTTATTCCTGGCCTATTGAGTCTTCTAGATGACCATGCAAATCCTCGTGTGCAAGCTCAT
GCAGGTGCTGCTTTAGTTAATTTCAGCGAAGATTGTCCAAAAACTATTCTCACGCGCTAT
CTTGACGGAATAATGAGTAAATTAGAAGCAATTTTAACAACAAAGTTTAATGAACTTGTT
GAGAAAGGCACAAAGTTGGTACTTGAACAGGTCGTTACAACAATTGCAAGCGTTGCTGAT
ACAACAGAAAAGGATTTTGTTGTTTATTACGATCGTCTCATGCCATGCTTGAAATATTTG
ATTGCCAATGCTAATACTGATGATTTGAAAATGTTACGAGGTAAAACAATTGAATGTGTC
AGTTTGATTGGTTTAGCTGTTGGAGCTGAAAAATTCATGAGTGATGCAAGTGAAATTATG
GATATGTTATTGAAGACACATACAGAAGGAAATTTACCTGATGACGACCCACAAACAACT
TATCTAATCTCGGCATGGGCTAGAATATGTAAAATTTTGGGCAAACAATTTGAACAATAT
TTGCCACTTGTTATGGGACCAGTAATGAAAACAGCAGCTATGAAACCTGAAGTCGCAGTT
TTAGATAATGATGAAATTCAAGATGTTGAAGCAGATCCAGATTGGCAATTTGTAAATTTA
AGTGA

>g9158.t6 Gene=g9158 Length=661
MAEEDTRFSSLLTSLLSIENDERTAAEEAYNNLATEVKVTLLLRALQNGQVSEDGSLMAA
VLLRRVFSSDFQNFFPKLTPEQQAELKQQILLLLQKDVSPNLRRKICEVVAEVTRNFIDD
DGNNQWPETLQLLFQCANTPNAILQESALRIFASVPGIFGNQQNHYLQVIKEMLMKYLDP
SSTPEVRFQAVRAVIAFILLNDKEVEIQKALSDLLPQIIMITADSIKAEEDQTLIKLLID
MSENVPKFLRPQLEAIFEMCINVFKSEDVEDSWRHLALEVMVSLSENASAMVRKKAEKYI
AALVPLVLKMMTELEDDEEWSVSDEIEDDDTGENNVIAESALDRLACGLGGKAILPHIVS
NIPTMLNNPDWRYRHAALMAISAAGEGCHKQMEAMLDSVTEGTLKYLADPHPRVRYAACN
AIGQMATDFAPVFEKKFHAHVIPGLLSLLDDHANPRVQAHAGAALVNFSEDCPKTILTRY
LDGIMSKLEAILTTKFNELVEKGTKLVLEQVVTTIASVADTTEKDFVVYYDRLMPCLKYL
IANANTDDLKMLRGKTIECVSLIGLAVGAEKFMSDASEIMDMLLKTHTEGNLPDDDPQTT
YLISAWARICKILGKQFEQYLPLVMGPVMKTAAMKPEVAVLDNDEIQDVEADPDWQFVNL
S

Protein features from InterProScan

Transcript Database ID Name Start End E.value
7 g9158.t6 Gene3D G3DSA:1.25.10.10 - 2 651 0.0e+00
3 g9158.t6 PANTHER PTHR10527 IMPORTIN BETA 4 660 0.0e+00
4 g9158.t6 PANTHER PTHR10527:SF22 IMPORTIN-5 4 660 0.0e+00
2 g9158.t6 Pfam PF18808 Importin repeat 267 356 0.0e+00
1 g9158.t6 Pfam PF13513 HEAT-like repeat 371 425 4.0e-07
6 g9158.t6 SMART SM01349 TOG_3 347 593 3.2e-03
5 g9158.t6 SUPERFAMILY SSF48371 ARM repeat 8 632 0.0e+00

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006606 protein import into nucleus BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values