General information for g920.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Chymotrypsin-1.
Parent gene
- The parent gene g920 is located on chr_3: 6863614..6864674 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g920 | g920.t1 | TTS | g920.t1 | 6863536 | 6863536 |
| chr_3 | g920 | g920.t1 | isoform | g920.t1 | 6863614 | 6864674 |
| chr_3 | g920 | g920.t1 | exon | g920.t1.exon1 | 6863614 | 6863667 |
| chr_3 | g920 | g920.t1 | cds | g920.t1.CDS1 | 6863614 | 6863667 |
| chr_3 | g920 | g920.t1 | exon | g920.t1.exon2 | 6863732 | 6864095 |
| chr_3 | g920 | g920.t1 | cds | g920.t1.CDS2 | 6863732 | 6864095 |
| chr_3 | g920 | g920.t1 | exon | g920.t1.exon3 | 6864152 | 6864293 |
| chr_3 | g920 | g920.t1 | cds | g920.t1.CDS3 | 6864152 | 6864293 |
| chr_3 | g920 | g920.t1 | exon | g920.t1.exon4 | 6864357 | 6864443 |
| chr_3 | g920 | g920.t1 | cds | g920.t1.CDS4 | 6864357 | 6864443 |
| chr_3 | g920 | g920.t1 | exon | g920.t1.exon5 | 6864504 | 6864557 |
| chr_3 | g920 | g920.t1 | cds | g920.t1.CDS5 | 6864504 | 6864557 |
| chr_3 | g920 | g920.t1 | exon | g920.t1.exon6 | 6864620 | 6864674 |
| chr_3 | g920 | g920.t1 | cds | g920.t1.CDS6 | 6864620 | 6864674 |
| chr_3 | g920 | g920.t1 | TSS | g920.t1 | 6864696 | 6864696 |
Sequences
>g920.t1 Gene=g920 Length=756
ATGATTCGTCAATTAGTAGTTTTTGCTTTGTTTGTTTCTGTGGCTTTTGCTGCACCACAA
AATAGAGAAAGAAGAATTGTTGGTGGAGTTGATAACGTCTTAGGGCAAGTACCATGGGCT
GTTTCACTTAGAACATTAGCAGGATTTCATTTCTGTACAGGATCAGTGGTCAGCAATTGG
TATGTCATCACTGCAGCTCATTGCGTTGCTGGTCGAGCTGCATCAACAATTCATTTAGTC
TTGGGAAGAGTTACACTTGACGGATTAACTGGAATGAATCGACAAGGTTTTAGAGTTGTT
ACTCATCCTGATTATAATGTTAATACAATGCAATTCGATGTGAGTTTAGTTCAAGTCTCA
GTAATAATCACGTTCAGCACAACAGTTCAATCAATTTTTGTTGGAAACTCATTCATTGGT
GAAGGACTTCCTGCAAAAGTGTCTGGTTGGGGTTCAACAAGTCAAGAGATCGGACCAACT
TCAAATAATCTCAGAACACTCGATACAACAACAATTTCAAATGAAAGTTGTAGAGCTCGT
CATACAGAAGCTAACGCAGCTCGCATTACATCAAGTAATTTGTGCACAAATAATGGATTT
GGTGAAGGATTCTGTCAAACAGGAGCTGGTGGATCTCTTGTATGGAATTCACAATTAATT
GGTATTGCTTCATGGAATGTACCTTGTGCTCTTGGCTTCCCTGATGTTTATGTGAGAATC
AGTGAAGTTCGAGATTGGATTGTTTCTGTGATTTAA
>g920.t1 Gene=g920 Length=251
MIRQLVVFALFVSVAFAAPQNRERRIVGGVDNVLGQVPWAVSLRTLAGFHFCTGSVVSNW
YVITAAHCVAGRAASTIHLVLGRVTLDGLTGMNRQGFRVVTHPDYNVNTMQFDVSLVQVS
VIITFSTTVQSIFVGNSFIGEGLPAKVSGWGSTSQEIGPTSNNLRTLDTTTISNESCRAR
HTEANAARITSSNLCTNNGFGEGFCQTGAGGSLVWNSQLIGIASWNVPCALGFPDVYVRI
SEVRDWIVSVI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g920.t1 | CDD | cd00190 | Tryp_SPc | 26 | 250 | 2.01626E-52 |
| 10 | g920.t1 | Gene3D | G3DSA:2.40.10.10 | - | 18 | 250 | 8.0E-49 |
| 2 | g920.t1 | PANTHER | PTHR24276 | POLYSERASE-RELATED | 7 | 247 | 7.8E-50 |
| 3 | g920.t1 | PANTHER | PTHR24276:SF78 | AT20289P-RELATED | 7 | 247 | 7.8E-50 |
| 6 | g920.t1 | PRINTS | PR00722 | Chymotrypsin serine protease family (S1) signature | 53 | 68 | 9.1E-5 |
| 5 | g920.t1 | PRINTS | PR00722 | Chymotrypsin serine protease family (S1) signature | 109 | 123 | 9.1E-5 |
| 4 | g920.t1 | PRINTS | PR00722 | Chymotrypsin serine protease family (S1) signature | 202 | 214 | 9.1E-5 |
| 1 | g920.t1 | Pfam | PF00089 | Trypsin | 26 | 247 | 2.3E-41 |
| 12 | g920.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 17 | - |
| 13 | g920.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 4 | - |
| 14 | g920.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 5 | 12 | - |
| 15 | g920.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 13 | 17 | - |
| 11 | g920.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 18 | 251 | - |
| 19 | g920.t1 | ProSitePatterns | PS00134 | Serine proteases, trypsin family, histidine active site. | 63 | 68 | - |
| 20 | g920.t1 | ProSiteProfiles | PS50240 | Serine proteases, trypsin domain profile. | 26 | 251 | 25.289 |
| 18 | g920.t1 | SMART | SM00020 | trypsin_2 | 25 | 247 | 2.5E-38 |
| 7 | g920.t1 | SUPERFAMILY | SSF50494 | Trypsin-like serine proteases | 6 | 251 | 7.66E-58 |
| 9 | g920.t1 | SignalP_EUK | SignalP-TM | SignalP-TM | 1 | 17 | - |
| 17 | g920.t1 | SignalP_GRAM_NEGATIVE | SignalP-noTM | SignalP-noTM | 1 | 17 | - |
| 8 | g920.t1 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 17 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004252 | serine-type endopeptidase activity | MF |
| GO:0006508 | proteolysis | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed