Gene loci information

Transcript annotation

  • This transcript has been annotated as Alanine–glyoxylate aminotransferase 2, mitochondrial.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g9242 g9242.t5 isoform g9242.t5 1055285 1057262
chr_1 g9242 g9242.t5 exon g9242.t5.exon1 1055285 1055874
chr_1 g9242 g9242.t5 cds g9242.t5.CDS1 1055848 1055874
chr_1 g9242 g9242.t5 exon g9242.t5.exon2 1055958 1056071
chr_1 g9242 g9242.t5 cds g9242.t5.CDS2 1055958 1056071
chr_1 g9242 g9242.t5 exon g9242.t5.exon3 1056247 1056812
chr_1 g9242 g9242.t5 cds g9242.t5.CDS3 1056247 1056756
chr_1 g9242 g9242.t5 exon g9242.t5.exon4 1056928 1057262
chr_1 g9242 g9242.t5 TSS g9242.t5 NA NA
chr_1 g9242 g9242.t5 TTS g9242.t5 NA NA

Sequences

>g9242.t5 Gene=g9242 Length=1605
GGTTAGATATGATTTTAGCAAGGTGAAGACACTTTGATTCATTGAAAACATTTGAATGTT
TGGAAATTCTAATTATTTTCAAAATTCCCAATATTGATAGAAAATTAGTTGATATTTGAT
TTATTTTGCATTATTTCTTTGGTTTATTATTAATTTAAAGTATTTTTTTACTAAATATGA
CGAGTTTTTTAAAAGTTTTCATAAAATATCTAAATTTGCAAAATGTAAACAAAAAAATTA
AAACAAAAAGTTTGTTTACCCCTTAAATTTCTCAATTTACAAAATTTGACAATTTCGATA
CAAATAAGGAGTAAATTAAATACTGAAACAATCAACACAATCAACATGGCATTATCCAGT
ACCAGGTCTAAAAAATGGTATTCATCATGTCATGAATCCCGATCCATATACCGGTATATG
GGGAGGAAGCAATTGTCGAGATTCGCCTGTTCAAACTAATCGCAAATGTGATTGCACACA
AGGGAAATGTCTTGCCGAAGATAATTACATTAATCAACTTGAAAGCGAGTTTAAATATTC
ATTGCCTAGAGGTAAATTGGCTGCATTGTTTGCTGAGTCAATTCAGGGTGTCGGCGGCAG
TGTGCAATTCCCGAGAAATTATCTCAAACGAGCGGCTGAAATTGTTCGAGCTGGTGGCGG
TCTCATTGTCAGTGATGAAGTTCAAACAGGCTTTGGAAGAACAGGTGAAAATTATTGGGG
TTTTGAGAATCATGGCATTGTGCCTGATATTGTGACAATGGCAAAAGGTATTGGAAATGG
CTTTCCACTTGGCGCTGTTGTTACCACACAGAAAATTGCACAAGTTATGACTGAGGCAGT
TCATTTTAATACATTCGGTGGAAATCCAATGGCTTGTGCGGTTGGAAAAGCCGTATTGGA
TGTGATTGACGAAGAGAAGCTACAACAGAATGCTTTGGATGTTGGAACATATTTACTCAA
GGGATTTGAAATATTACGTGAAAAATATGACATTATTGGCGATGTAAGAGGCAAGGCTCG
ATTGACATTTTCAATACTTTGATCTCTTCCAAAATGCAAATCTACTTCTACCACACTGTT
TCCATCATAGTCGTCATCATTTGTCGTCGTTTGCTCATTTGCATGCGATGTGTTGTCAAA
ACGAGCGAATATCACATTCGAGTGATGCATGAAGCGTCGCTGGTTTCTTATCGCTGCCAT
CAAGCGTGGAATATGTCTGTCATCATAATAGACGATATAAATCAGTGTCATAAACAGCGT
CACAAGAAAAGCGAGCCGAAAATGAATGTGAAAACGTGACCACTCGCATTCGGCGTAAAT
GCAGTGCCCGAAATGAAATAAAATTTTGATTGGCCTGAAAAAGAACATAAAAGAGTCAGA
AAATTAAGTCAAAACTTGTACTCACTTTGAGAATTTTTATTAAGCATCGATTCACGAAGT
TGTTCCATTAAATTAGAACTTAATTCTTTATATTCAAATCGATCGACAATAATGAGCTGC
AAATAATGCTGATTCTTTTCTTTTTCTTTTCCCAATGTCACACTGCAATGATAAATGACC
TTTTTCCGATCTGTTTCACTTGTTGCTGCATTGATTGCTGAAATT

>g9242.t5 Gene=g9242 Length=216
MNPDPYTGIWGGSNCRDSPVQTNRKCDCTQGKCLAEDNYINQLESEFKYSLPRGKLAALF
AESIQGVGGSVQFPRNYLKRAAEIVRAGGGLIVSDEVQTGFGRTGENYWGFENHGIVPDI
VTMAKGIGNGFPLGAVVTTQKIAQVMTEAVHFNTFGGNPMACAVGKAVLDVIDEEKLQQN
ALDVGTYLLKGFEILREKYDIIGDVRGKARLTFSIL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
7 g9242.t5 Gene3D G3DSA:3.40.640.10 - 30 176 6.6E-65
6 g9242.t5 Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase 177 208 6.6E-65
2 g9242.t5 PANTHER PTHR45688:SF3 ALANINE–GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL 1 209 7.4E-84
3 g9242.t5 PANTHER PTHR45688 - 1 209 7.4E-84
1 g9242.t5 Pfam PF00202 Aminotransferase class-III 47 208 6.3E-48
5 g9242.t5 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 92 130 -
4 g9242.t5 SUPERFAMILY SSF53383 PLP-dependent transferases 47 209 3.02E-55

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0008483 transaminase activity MF
GO:0003824 catalytic activity MF
GO:0030170 pyridoxal phosphate binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values