Gene loci information

Transcript annotation

  • This transcript has been annotated as Cytokine receptor.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g9256 g9256.t1 TTS g9256.t1 1327687 1327687
chr_1 g9256 g9256.t1 isoform g9256.t1 1328324 1332169
chr_1 g9256 g9256.t1 exon g9256.t1.exon1 1328324 1328373
chr_1 g9256 g9256.t1 cds g9256.t1.CDS1 1328324 1328373
chr_1 g9256 g9256.t1 exon g9256.t1.exon2 1328446 1328581
chr_1 g9256 g9256.t1 cds g9256.t1.CDS2 1328446 1328581
chr_1 g9256 g9256.t1 exon g9256.t1.exon3 1328658 1328888
chr_1 g9256 g9256.t1 cds g9256.t1.CDS3 1328658 1328888
chr_1 g9256 g9256.t1 exon g9256.t1.exon4 1328959 1330169
chr_1 g9256 g9256.t1 cds g9256.t1.CDS4 1328959 1330169
chr_1 g9256 g9256.t1 exon g9256.t1.exon5 1330285 1332169
chr_1 g9256 g9256.t1 cds g9256.t1.CDS5 1330285 1332169
chr_1 g9256 g9256.t1 TSS g9256.t1 NA NA

Sequences

>g9256.t1 Gene=g9256 Length=3513
ATGATAGTAACTAGCAGCTTAATACAATCAGTTAATTGTATAAGAGGATGGACTGATCCA
AAAGGACAAATAATAATTGAGAAGGGAACCAGATTGAGCATTAAATGTGTAGTAGAAAGT
GACAATGAAGTTTATTCCAACACACAATTAAGTAAAAGACTTGGCTTCTTCTTCCAAGGA
AATGTGAAAGTTGATCAAAAATATATCAATATTTTAAATGATACTGCAATTGAGTTGGTT
ATACCAAAAGTGCCTGAGCAAGAGTCAATGTTTTTATGCAAATTTGACGATGAAAAAGGA
ATTACATATAATGATGTTAAAGTTGGTCACAAACCAGATGAGATTGAACACATAGATTGT
GTTTCACGCAATTGGGAAAATTTAACATGCACTTTCAAAAAGCCATATAATCCAGTTTAT
GTGCAATATGAGCTTAAATATCGTCTCGATAAATCAAGTTTGGTACACATTTGTCAAGTA
GAATTATCTGATCCAGATATTTTCCAATGCACTGTTGAAGAAGTTTCATATCGTCGTTAC
AGTGAAAATTTTATATTAACACTCACTTCAACTAATCTTTTTGGAACAAGAAATCAATCA
TTTGAGTTTGATAATTTTGCAAGTGTTATTCCCGGAAAAGTGGAAAATCTTAATAAAATT
GAAACATCTGATAATATAACTATATCATGGTTGGCATCAAAGAAACTTGCGGTATTTCCC
AAAAATTTTGACGTTGAAATCTCTATCAATTCTTCACTCGAATGTAATGCTAAAGAAGAG
AAAATTTTATTGCGAAATTTCACTACTCATAAAGAAAAATCAAGTCGCAGTGTTGAAAAG
AATATATTTGAATATACCATACCAGTCAAGTTTCCCAACAAATGGTATGATGTAGGTGTC
AGAATGAAAGTTGCTATGGCAAAAGATGAAGAGAAAATGTGGAGTGAAATGGAAAAAATT
CAAGCTTTCACCTTATCACGTGCTCCTGACAATCCGCCAGAAATTAACATAGGATCATTC
AATATTCTTCCAAATGGTGATGCTTATATTTACTGGAAGCACTTACATACTTGTTCATGG
AATGGAAATGGTTTTAACTATTCTATAAAGTCAAGTGGCAAACAAGAAAATCCTTCTGAG
CAACATTTGACCTATGCTGTTTACCGTCAGGATTTCAATAATCGCACAGAAGATACGACA
TTTTATATAAGAAGCAACAATTCTGAAGGAATGTCTCGCGATGCAAGTGTTTTAGTTATC
CCTGGTAAAAATCGACGACTTCGTGGGCCTACAAAAATTAACAAAAAGTCTATAAATGGA
ACTTATGTTTTGACATGGTCACCACCTGAATATAACGTCGAAGAAATAATTTCTTATACA
GTTTTTTGGTGCACATCAAAAACTGAACTCATAAATAGCTGTGAAAGTTCAATCGATTTC
AAAGAACATAAACCACATGAGACAACCTTTATGCATGAATCGGATCAGACTGTCAACTTT
GCGATTTCTGCTAATTCTAGAACCTCAACTTCGGGTATGATGTGGGCAAAATGCACAACA
GCAAATAGCTATGAGATAGGAAAAATCCGCACAGCACGAATTTCACGGCTTACATCGAAA
GAGATTGAAGTAGAGTGGAATTTAGATTGTACAGATTTGGGTATCGTTGCGGGCTATCAA
ATTGAGTATTGCCCAACAAATAAGCCTAAAACATTAGAGTGCATTACTGGCTCAGAAAAC
AGAACAAACATCACGACTCACGTCGAAAAATATACTTTGAGTGATCTTAAGCCTTATACA
ACTTATAAAATTGTCATTCGCATGTTTTCAAATTCAACAATGGGCCCACCGAGCGAACCG
TTAGCTAATACGACGCTTGAAGACGCTCCTTCTGAAGTTCGTAATTTGATTGCGCGTAAC
GTTGGAAACACGTCTGTTGATCTCTATTGGGATCCACCTGAGGAAATCAATGGTGTTCTT
GGTTCTTATGACATCTGGAAAAATGGAAATGTGCATCATCGCATTGAAATCCCAAAGACT
TTTGATAGCGAACATTTGAACGTGACGAAAATGAATTACACTCTTGAAGGATTATTGCCA
TATGAGGATTATGAAATTATTGTGCTTGCGTGTACAAATAAGTGTTCTGTGGCTACTACA
ACAAAGATTAGAACAACAATCGGTGCACCTGGCGGTTTCAAAAAGCAGCCAACATTAAAT
GATAAAGGATCAACTATTTTTAATAGTACTTACACAAGTGGTATTATAAGCTGGGATGAA
CCGGAATTTAAAGGTGGTAATCTAGATTTTTATGAGTTAAAAACGAGTTTTCAAGGCAAT
GATGGTACCATAGAAAAGAATATTATAAAATTAAAATCAAATGAATGCTTTGTTGAGAAA
TTGTGTGTCACTAATGTTACTGGAACCGTCCGATTCTCAGTTCGCGCTGTCAATTTTGTT
ATGACACCACATGCAAAAGATCGAGACTTTTTGATCACAGGAAAAAAGGTTGAAAAAAAT
TCACAAAATTATTGTGTCAACGATGAAGTGCTTCTAGAATCAATGAGAATTGCATCACAA
ATTGATCCCTTTGGATACTATTTATATGGTCCATGGTCTGAATCTTCAGGTCACACTTGC
CATTATAATAATATCAATTCACGGCAGTACATCTTAATAATGATTTTAATGGTCGCATCA
CTCGTATTTGTTGTCATGGTATTTTATTTATATAGACGAATTAAAGACATGAAAGACATT
TTAGTACAAATGCCGCCAGGACTCGAAGACCTTCAATCAGAAAAAATCAAAAAGGGAAAA
GATTCGAGTACTGATAAAATTGGAAAGCCTGATTTGCTTCATAATATTGAGAGTCCATAT
ACTATGAATGAAGATGAGCATGGACGATTATTAAAGAGATCATTGAATGGAAGCATTAAT
GGTGCTGATTGCAGTAGTAGCATACACAGTGAAAGTAGTAGTATGGATCAAGCCGAAATG
GCAGATGAAATTGAATACAATGACCTTGGTCAGCAAAATAACATGAGTGATGGTGAAATT
GAGACATCAACGGCAGCAGCTAATCAACGACCTCAGAGTTTCATCATGAACTCATCAGTT
CCTAAAGAAATTGCTCCTATACTAATATCACCAGAATCAATATCATCGTCATCACCACCT
ATTACAGATAATATTCCTAAACCAAATTCATTAATACATCAACCTAAGACGCCAGTGAGT
GTTTATGTCGCACCACCAGTAATGCATTCAACTCCAATTCCTCCACAAATTAATAGTAAT
GGTTATGTGACGCATTCAATGTTAAACCCGATTCAATCTAACAATGGATATACGCAACTT
AATGCATTAGGAAAACCAATAATCAACAATGATCGGCATTTTATTGATAAAATGAGCATA
AAAACACCAATTGTTGCAACAACAGATCAAGAAGGAATTTCAGGTTATGTGACACACAAA
CAGCTTTCTGATTTCGGACATCGAATGCAATAA

>g9256.t1 Gene=g9256 Length=1170
MIVTSSLIQSVNCIRGWTDPKGQIIIEKGTRLSIKCVVESDNEVYSNTQLSKRLGFFFQG
NVKVDQKYINILNDTAIELVIPKVPEQESMFLCKFDDEKGITYNDVKVGHKPDEIEHIDC
VSRNWENLTCTFKKPYNPVYVQYELKYRLDKSSLVHICQVELSDPDIFQCTVEEVSYRRY
SENFILTLTSTNLFGTRNQSFEFDNFASVIPGKVENLNKIETSDNITISWLASKKLAVFP
KNFDVEISINSSLECNAKEEKILLRNFTTHKEKSSRSVEKNIFEYTIPVKFPNKWYDVGV
RMKVAMAKDEEKMWSEMEKIQAFTLSRAPDNPPEINIGSFNILPNGDAYIYWKHLHTCSW
NGNGFNYSIKSSGKQENPSEQHLTYAVYRQDFNNRTEDTTFYIRSNNSEGMSRDASVLVI
PGKNRRLRGPTKINKKSINGTYVLTWSPPEYNVEEIISYTVFWCTSKTELINSCESSIDF
KEHKPHETTFMHESDQTVNFAISANSRTSTSGMMWAKCTTANSYEIGKIRTARISRLTSK
EIEVEWNLDCTDLGIVAGYQIEYCPTNKPKTLECITGSENRTNITTHVEKYTLSDLKPYT
TYKIVIRMFSNSTMGPPSEPLANTTLEDAPSEVRNLIARNVGNTSVDLYWDPPEEINGVL
GSYDIWKNGNVHHRIEIPKTFDSEHLNVTKMNYTLEGLLPYEDYEIIVLACTNKCSVATT
TKIRTTIGAPGGFKKQPTLNDKGSTIFNSTYTSGIISWDEPEFKGGNLDFYELKTSFQGN
DGTIEKNIIKLKSNECFVEKLCVTNVTGTVRFSVRAVNFVMTPHAKDRDFLITGKKVEKN
SQNYCVNDEVLLESMRIASQIDPFGYYLYGPWSESSGHTCHYNNINSRQYILIMILMVAS
LVFVVMVFYLYRRIKDMKDILVQMPPGLEDLQSEKIKKGKDSSTDKIGKPDLLHNIESPY
TMNEDEHGRLLKRSLNGSINGADCSSSIHSESSSMDQAEMADEIEYNDLGQQNNMSDGEI
ETSTAAANQRPQSFIMNSSVPKEIAPILISPESISSSSPPITDNIPKPNSLIHQPKTPVS
VYVAPPVMHSTPIPPQINSNGYVTHSMLNPIQSNNGYTQLNALGKPIINNDRHFIDKMSI
KTPIVATTDQEGISGYVTHKQLSDFGHRMQ

Protein features from InterProScan

Transcript Database ID Name Start End E.value
17 g9256.t1 CDD cd00063 FN3 533 625 4.6169E-10
18 g9256.t1 CDD cd00063 FN3 630 726 4.56801E-9
13 g9256.t1 Coils Coil Coil 1169 1170 -
12 g9256.t1 Gene3D G3DSA:2.60.40.10 Immunoglobulins 109 211 5.4E-10
10 g9256.t1 Gene3D G3DSA:2.60.40.10 Immunoglobulins 423 521 5.6E-5
11 g9256.t1 Gene3D G3DSA:2.60.40.10 Immunoglobulins 522 628 2.4E-17
9 g9256.t1 Gene3D G3DSA:2.60.40.10 Immunoglobulins 629 731 1.9E-13
4 g9256.t1 PANTHER PTHR46957 CYTOKINE RECEPTOR 184 671 1.2E-28
3 g9256.t1 PANTHER PTHR46957 CYTOKINE RECEPTOR 622 767 1.2E-28
2 g9256.t1 Pfam PF00041 Fibronectin type III domain 531 618 1.7E-9
1 g9256.t1 Pfam PF00041 Fibronectin type III domain 631 714 1.4E-8
15 g9256.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 1 889 -
16 g9256.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 890 911 -
14 g9256.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 912 1170 -
26 g9256.t1 ProSiteProfiles PS50853 Fibronectin type-III domain profile. 426 526 6.809
24 g9256.t1 ProSiteProfiles PS50853 Fibronectin type-III domain profile. 528 628 15.44
25 g9256.t1 ProSiteProfiles PS50853 Fibronectin type-III domain profile. 629 729 13.586
22 g9256.t1 SMART SM00060 FN3_2 211 310 120.0
20 g9256.t1 SMART SM00060 FN3_2 427 511 47.0
21 g9256.t1 SMART SM00060 FN3_2 526 617 0.028
23 g9256.t1 SMART SM00060 FN3_2 630 716 5.1E-7
6 g9256.t1 SUPERFAMILY SSF49265 Fibronectin type III 109 200 1.45E-6
5 g9256.t1 SUPERFAMILY SSF49265 Fibronectin type III 430 512 7.54E-5
8 g9256.t1 SUPERFAMILY SSF49265 Fibronectin type III 533 714 3.94E-31
7 g9256.t1 SUPERFAMILY SSF49265 Fibronectin type III 679 801 1.38E-8
19 g9256.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 889 911 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005515 protein binding MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values