Gene loci information

Transcript annotation

  • This transcript has been annotated as Proline dehydrogenase 1, mitochondrial.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g9282 g9282.t1 TTS g9282.t1 1405921 1405921
chr_1 g9282 g9282.t1 isoform g9282.t1 1406797 1409949
chr_1 g9282 g9282.t1 exon g9282.t1.exon1 1406797 1407002
chr_1 g9282 g9282.t1 cds g9282.t1.CDS1 1406797 1407002
chr_1 g9282 g9282.t1 exon g9282.t1.exon2 1407058 1407427
chr_1 g9282 g9282.t1 cds g9282.t1.CDS2 1407058 1407427
chr_1 g9282 g9282.t1 exon g9282.t1.exon3 1407482 1407643
chr_1 g9282 g9282.t1 cds g9282.t1.CDS3 1407482 1407643
chr_1 g9282 g9282.t1 exon g9282.t1.exon4 1407709 1407883
chr_1 g9282 g9282.t1 cds g9282.t1.CDS4 1407709 1407883
chr_1 g9282 g9282.t1 exon g9282.t1.exon5 1407948 1408245
chr_1 g9282 g9282.t1 cds g9282.t1.CDS5 1407948 1408245
chr_1 g9282 g9282.t1 exon g9282.t1.exon6 1408321 1408538
chr_1 g9282 g9282.t1 cds g9282.t1.CDS6 1408321 1408538
chr_1 g9282 g9282.t1 exon g9282.t1.exon7 1408781 1408902
chr_1 g9282 g9282.t1 cds g9282.t1.CDS7 1408781 1408902
chr_1 g9282 g9282.t1 exon g9282.t1.exon8 1409650 1409949
chr_1 g9282 g9282.t1 cds g9282.t1.CDS8 1409650 1409949
chr_1 g9282 g9282.t1 TSS g9282.t1 1410141 1410141

Sequences

>g9282.t1 Gene=g9282 Length=1851
ATGGCTATGGCAAGGAGTTGTGGAAAATTAGGACCTTCAATGAAAATTTTCTTATTGAAT
AAGAATTTCCAATCAAACTTAAAATATCTGTCGACTGCATCAATTCTAAAGGCACCACTG
CATAAAACGGCAGCTGTCAATCAGCCACAAGTTGCTAAAGTCGGCAAAAAAGACTCGTTA
GATACTTCATTCAATAATCCTATTGATGCATTCAAGTCAAAGACAACTTTTGAGCTGATT
CGAGCCTATTTCGTGTATTTATTATGCTCTTCAGAATATTTAGTTGAAAACAACATGAAG
ATCATGAAATTGATGAATGCTGTTCTAGGTGACAAAATTTTTAATTTAATCATGAAGTCA
ACGTTTTATGGACATTTCGTAGCAGGCGAGAATCAAGAAAAAATCGTCCCATGTCTCGAA
AGATTAAGATCGTTTGGTGTCAAGCCAATTTTAGATTACTCAGTTGAGGAAGATTTATCG
CAAGAAGAAGCTGAAGAACGTGAAGTTTCAGCATCTGTTCCAACAGCTGCACCAGCACCA
TCTGATCCAGGTCATTTGCCGCAATATGTGGTCGATAAAACTTTTGCTGATCGACGCTAT
AAAGTTCTGGGAGCAAGAACATATTTTTATCTGAATGAAGCGACTTGCGAACGAAATATG
GAGACATTTATTCGCTGTTTGGAAGCTGTCAAATATAGCAGTTTCGGCACAGGCATTACA
GCCATCAAATTAACTGCACTTGGTCGTCCACACTTATTGCTACAAATCTCTGAAGTTATT
CAACGAACTCGTAATTATATGATAGAAATTGCAGGTGGAACAGGAAATGTTTTGACACAT
CATAAAACAATTAAAGATTTGGAAACATATTTCGGAACAATGGGTGATAATAAAGATGTC
AAGGATTTTTTAAAGCAAGTTACAACTGATAAGGAAGGAATATTGCATTTATTCCCATGG
AGTGGAATTATAAATGAAGAGCATCAATTGTCTGATACTTTCCGTGTTCCTGACCCAAAA
ACTGGTCAAATGCGTCGTTTGACATCACAAATACCACATAAAGAAGAAGAAATGTTTAGA
AATATGATACGTCGATTAAATAACATTGTACAAGTCGCTGAGGAATTAGACGTAAGAATC
ATGATTGATGCAGAACAGACATATTTTCAACCAGCTATTTCTCGAATTACATTAGAACTT
ATGAGAAAGTATAATACAAAGAAAGCAATTGTATTCAACACTTACCAATGCTATTTGAAA
GATGCTTATCGTGAAGTTTGTACTGATCTTGAACAAGCATCACGTCAGAACTTTTATTTT
GGTGCAAAATTAGTAAGAGGTGCATATATGGAACAAGAAAGAGCTCGTGCATCGGCTTTG
GGCTATGTAGATCCAATTAATCCAAATTATGAAGCAACAACTGAGATGTATCACAAGACT
TTGACAGAATGCTTGCGTAGAATCAAGAAATTAAAAGACAGTGGTGCTGATCCAAAAAAA
ATCGCTATAATGGTTGCATCGCACAATGAAGACACAGTTCGATTTGCTATTGAGAAAATG
AAAGAGATTGGCATTTCACCTGAAGATAAGGTCATTTGTTTCGGACAGTTATTAGGAATG
TGTGATTATATTACTATGCCATTAGGTCAAGCGGGATATTCTGCTTACAAATATGTTCCA
TACGGACCTGTTAAAGAAGTGCTGCCATATTTAAGTCGACGTGCACTCGAAAACAAAGGA
GTACTTAAAAAGATTCAGAAAGAAAAGAGATTATTAAAAACAGAAATTTGGCGGAGACTC
TCACGAGGACAACTATTTTATCGTCCAAAGGGTGATTATATACCAATTTAA

>g9282.t1 Gene=g9282 Length=616
MAMARSCGKLGPSMKIFLLNKNFQSNLKYLSTASILKAPLHKTAAVNQPQVAKVGKKDSL
DTSFNNPIDAFKSKTTFELIRAYFVYLLCSSEYLVENNMKIMKLMNAVLGDKIFNLIMKS
TFYGHFVAGENQEKIVPCLERLRSFGVKPILDYSVEEDLSQEEAEEREVSASVPTAAPAP
SDPGHLPQYVVDKTFADRRYKVLGARTYFYLNEATCERNMETFIRCLEAVKYSSFGTGIT
AIKLTALGRPHLLLQISEVIQRTRNYMIEIAGGTGNVLTHHKTIKDLETYFGTMGDNKDV
KDFLKQVTTDKEGILHLFPWSGIINEEHQLSDTFRVPDPKTGQMRRLTSQIPHKEEEMFR
NMIRRLNNIVQVAEELDVRIMIDAEQTYFQPAISRITLELMRKYNTKKAIVFNTYQCYLK
DAYREVCTDLEQASRQNFYFGAKLVRGAYMEQERARASALGYVDPINPNYEATTEMYHKT
LTECLRRIKKLKDSGADPKKIAIMVASHNEDTVRFAIEKMKEIGISPEDKVICFGQLLGM
CDYITMPLGQAGYSAYKYVPYGPVKEVLPYLSRRALENKGVLKKIQKEKRLLKTEIWRRL
SRGQLFYRPKGDYIPI

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g9282.t1 Gene3D G3DSA:3.20.20.220 - 343 603 0
2 g9282.t1 PANTHER PTHR13914 PROLINE OXIDASE 46 604 0
3 g9282.t1 PANTHER PTHR13914:SF22 PROLINE DEHYDROGENASE 1, MITOCHONDRIAL 46 604 0
1 g9282.t1 Pfam PF01619 Proline dehydrogenase 140 585 0
4 g9282.t1 SUPERFAMILY SSF51730 FAD-linked oxidoreductase 129 608 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006562 proline catabolic process BP
GO:0004657 proline dehydrogenase activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values