General information for g9326.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Xanthine dehydrogenase.
Parent gene
- The parent gene g9326 is located on chr_1: 1864127..1868061 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9326 | g9326.t1 | isoform | g9326.t1 | 1864127 | 1868061 |
| chr_1 | g9326 | g9326.t1 | exon | g9326.t1.exon1 | 1864127 | 1864448 |
| chr_1 | g9326 | g9326.t1 | cds | g9326.t1.CDS1 | 1864127 | 1864448 |
| chr_1 | g9326 | g9326.t1 | exon | g9326.t1.exon2 | 1864755 | 1865051 |
| chr_1 | g9326 | g9326.t1 | cds | g9326.t1.CDS2 | 1864755 | 1865051 |
| chr_1 | g9326 | g9326.t1 | exon | g9326.t1.exon3 | 1865550 | 1865921 |
| chr_1 | g9326 | g9326.t1 | cds | g9326.t1.CDS3 | 1865550 | 1865921 |
| chr_1 | g9326 | g9326.t1 | exon | g9326.t1.exon4 | 1866002 | 1866198 |
| chr_1 | g9326 | g9326.t1 | cds | g9326.t1.CDS4 | 1866002 | 1866198 |
| chr_1 | g9326 | g9326.t1 | exon | g9326.t1.exon5 | 1866720 | 1867278 |
| chr_1 | g9326 | g9326.t1 | cds | g9326.t1.CDS5 | 1866720 | 1867278 |
| chr_1 | g9326 | g9326.t1 | exon | g9326.t1.exon6 | 1867482 | 1867784 |
| chr_1 | g9326 | g9326.t1 | cds | g9326.t1.CDS6 | 1867482 | 1867784 |
| chr_1 | g9326 | g9326.t1 | exon | g9326.t1.exon7 | 1867838 | 1867950 |
| chr_1 | g9326 | g9326.t1 | cds | g9326.t1.CDS7 | 1867838 | 1867950 |
| chr_1 | g9326 | g9326.t1 | exon | g9326.t1.exon8 | 1868011 | 1868061 |
| chr_1 | g9326 | g9326.t1 | cds | g9326.t1.CDS8 | 1868011 | 1868061 |
| chr_1 | g9326 | g9326.t1 | TSS | g9326.t1 | NA | NA |
| chr_1 | g9326 | g9326.t1 | TTS | g9326.t1 | NA | NA |
Sequences
>g9326.t1 Gene=g9326 Length=2214
ATGGATTTGGCTGTAACAACTGTTGAAGGAATTGCAGCACAAAGAGATCGATTGCATCCA
GTTCAAGAGAGAATTGCTAAAGCTCATGGTTCACAATGTGGTTTCTGTACACCTGCATGG
TCATGTCAATGTATGCACTACTTAGAAAATTCATCAAAACCATCAATGAAAGAACTTGAA
ATTGCAATGCAAGGAAACTTGTGTCGATGCACTGGCTATCGACCAATCATTGAAGGTTAT
CGAACATTTACAAAAGAATTCGGCAATGAAGAAGTTTGTGGAATGGGTGAAAAAATGTTG
CAAAGTCAATGGAGGAAAATTGAAGTCACAAAAGATGGGTTGAAAATTGGAGCTGCTGTG
ACTTTGACTGAGATTGAAAATTTCATTGAAAGTAAAACAGACCAAAATGTTATTGAAAAA
TCAATCGTTGAAATGTTGCATTGGTTTGCAGGATCACAAGTTCGGAATGTTGCTTCAATT
GGTGGAAATATCGTTACAAGCTCACCAATATCTGATTTAAATCCAATTTTACTTGCTGCA
GGTGCTAAATTAGAAGTTCAAAGTCTAAAAGATGGCAAAAGAATAATAAAAATGGATGAA
AATTTTTTCACTGGATATCTCTCAAGTGATCAACCTCTGACTGATCCAATTCATCGTCCC
AAAATTCATTCATCAGCATTACAACAAGCAACAGGAGAAGCAATTTATTGTGATGACATT
CCAAAACATGAAAATGAACTTTACCTTGCACTTGTTTTAAGCACAAAAGCTCATGCTAAA
ATAATTTCAATTGATGCAAGTGAAGCTCTTAAACAACCTGGAATTCATGCCTTCTTTACA
GCAAAAGACGTTGATCAAACTAGTTATACCAACGGTTTTATGGGAAAGGATGAAGAAATT
TTCATTAGTGAAACTGTTACAAGTGAAGGTCAAATTTTAGGAGCAATTGTTGGTGACAAT
CAAATTATAGCTCAAAGAGCAGCGAAATTAGGTTTTCCAAAAACGCGTTACAATGGAGAT
ATTAAGAAAACTTTAAATGAAGCAGATCATGTAATTGAAGGAGAAGTTCGTTTAGGTGGT
CAAGAACATTTTTACATTGAAACTCATTCAAATCTTGCAATTCCTAAAGATGCAGATGAA
ATTGAAATTTTTTCATCAACTCAACATCCATGTGAAATGCAACGTCATTTCTCAAAACAA
ACACCAGATCGAAACACGGCTTTTAGAGGTTTCGGATCACCTCAAGGAATGTTGGCAGCT
GAGACAATGATTAGAGATGTTGCACGAATTACAGGCAAAGATTATCTTGAAATTATGGAC
CTAAATATGTGTGAAAATGGCTATGTTCTGCATTATAAACAAATACTTGAAAACTGCAAT
ATCAGAAGATGCTTTGAAGAAGTAAAAATTAATTCTGATTTAGAAAACAGACGAAAATCT
GTTGCAAAAATCAACTCTGAAAATCGATGGAAGAAGCGAGGAATTTCGATCGTTAACAAT
CTTTATCCCATAGGCTTTCCTCCTAAATTTTTAAATCAAGGTGGTACTCGTCCATATTTA
TCTGATGGTTCAGTTTTGGTCTCTCATGGTGGAGTCGAAATGGGTCAAGGACTGCATACT
AAGATGATTCAAGTAGCATCACGAGTATTGAAAGTTCCGATGGAAATTATTCACATTCAA
GAAACAGCAACTGACAAAGTTCCTAATGCTATCAGCACTGCAGCTTCTGTAAGTTCCGAT
TTATATGTTTCTGAAGTTGAAATTGATTGTTTGACTGGCGATCATCAAGTGATAAGAACT
GACATTGTGATGGATGTTGGAAGCTCATTGAATCCAGCAATCGACATTGGTCAAATTGAA
GGTGCTTTCATGCAAGGTTATGGATTATTTGTGCTTGAAGAATTGATTTATTCGCCAAAT
GGAACTTTGTATTCACGAGGTCCAGGCATGTACAAAATTCCAAGTTTCGGCAACATTCCA
GCTGAATTCAATGTTTCACTGCTCACTGATGCACCAAATCCGAGAGCTGTGTTTTCATCT
CGAGCTGTTGAAGCAATTGGAGCAGCAAGAAAGGAAGAAGGCTTGGATTCACACTTTTAT
TTACAAGCACCAGCAACAGCAGCAAGAATTAGAGTCGCATGTCAAGATAAAATTGTTGAA
AAGTTTGAGTCATTAAAAGATGAAAATTTGACACCATGGAATGTTGATTTATAG
>g9326.t1 Gene=g9326 Length=737
MDLAVTTVEGIAAQRDRLHPVQERIAKAHGSQCGFCTPAWSCQCMHYLENSSKPSMKELE
IAMQGNLCRCTGYRPIIEGYRTFTKEFGNEEVCGMGEKMLQSQWRKIEVTKDGLKIGAAV
TLTEIENFIESKTDQNVIEKSIVEMLHWFAGSQVRNVASIGGNIVTSSPISDLNPILLAA
GAKLEVQSLKDGKRIIKMDENFFTGYLSSDQPLTDPIHRPKIHSSALQQATGEAIYCDDI
PKHENELYLALVLSTKAHAKIISIDASEALKQPGIHAFFTAKDVDQTSYTNGFMGKDEEI
FISETVTSEGQILGAIVGDNQIIAQRAAKLGFPKTRYNGDIKKTLNEADHVIEGEVRLGG
QEHFYIETHSNLAIPKDADEIEIFSSTQHPCEMQRHFSKQTPDRNTAFRGFGSPQGMLAA
ETMIRDVARITGKDYLEIMDLNMCENGYVLHYKQILENCNIRRCFEEVKINSDLENRRKS
VAKINSENRWKKRGISIVNNLYPIGFPPKFLNQGGTRPYLSDGSVLVSHGGVEMGQGLHT
KMIQVASRVLKVPMEIIHIQETATDKVPNAISTAASVSSDLYVSEVEIDCLTGDHQVIRT
DIVMDVGSSLNPAIDIGQIEGAFMQGYGLFVLEELIYSPNGTLYSRGPGMYKIPSFGNIP
AEFNVSLLTDAPNPRAVFSSRAVEAIGAARKEEGLDSHFYLQAPATAARIRVACQDKIVE
KFESLKDENLTPWNVDL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 20 | g9326.t1 | Gene3D | G3DSA:3.30.365.10 | Aldehyde Oxidoreductase; domain 4 | 1 | 104 | 0.000 |
| 18 | g9326.t1 | Gene3D | G3DSA:3.30.465.10 | - | 105 | 211 | 0.000 |
| 23 | g9326.t1 | Gene3D | G3DSA:3.30.365.10 | Aldehyde Oxidoreductase; domain 4 | 212 | 331 | 0.000 |
| 22 | g9326.t1 | Gene3D | G3DSA:3.30.365.10 | Aldehyde Oxidoreductase; domain 4 | 332 | 401 | 0.000 |
| 19 | g9326.t1 | Gene3D | G3DSA:3.30.365.10 | Aldehyde Oxidoreductase; domain 4 | 402 | 582 | 0.000 |
| 21 | g9326.t1 | Gene3D | G3DSA:3.30.365.10 | Aldehyde Oxidoreductase; domain 4 | 583 | 737 | 0.000 |
| 8 | g9326.t1 | PANTHER | PTHR11908 | XANTHINE DEHYDROGENASE | 4 | 398 | 0.000 |
| 11 | g9326.t1 | PANTHER | PTHR11908:SF100 | XANTHINE DEHYDROGENASE | 4 | 398 | 0.000 |
| 7 | g9326.t1 | PANTHER | PTHR11908 | XANTHINE DEHYDROGENASE | 405 | 583 | 0.000 |
| 10 | g9326.t1 | PANTHER | PTHR11908:SF100 | XANTHINE DEHYDROGENASE | 405 | 583 | 0.000 |
| 9 | g9326.t1 | PANTHER | PTHR11908 | XANTHINE DEHYDROGENASE | 583 | 721 | 0.000 |
| 12 | g9326.t1 | PANTHER | PTHR11908:SF100 | XANTHINE DEHYDROGENASE | 583 | 721 | 0.000 |
| 5 | g9326.t1 | Pfam | PF01799 | [2Fe-2S] binding domain | 7 | 79 | 0.000 |
| 1 | g9326.t1 | Pfam | PF00941 | FAD binding domain in molybdopterin dehydrogenase | 105 | 208 | 0.000 |
| 6 | g9326.t1 | Pfam | PF01315 | Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain | 231 | 330 | 0.000 |
| 4 | g9326.t1 | Pfam | PF02738 | Molybdopterin-binding domain of aldehyde dehydrogenase | 338 | 399 | 0.000 |
| 2 | g9326.t1 | Pfam | PF02738 | Molybdopterin-binding domain of aldehyde dehydrogenase | 405 | 582 | 0.000 |
| 3 | g9326.t1 | Pfam | PF02738 | Molybdopterin-binding domain of aldehyde dehydrogenase | 582 | 660 | 0.000 |
| 24 | g9326.t1 | ProSiteProfiles | PS51387 | PCMH-type FAD-binding domain profile. | 105 | 245 | 11.307 |
| 17 | g9326.t1 | SMART | SM01008 | Ald_Xan_dh_C_2 | 231 | 343 | 0.000 |
| 13 | g9326.t1 | SUPERFAMILY | SSF47741 | CO dehydrogenase ISP C-domain like | 19 | 90 | 0.000 |
| 16 | g9326.t1 | SUPERFAMILY | SSF56176 | FAD-binding/transporter-associated domain-like | 104 | 209 | 0.000 |
| 15 | g9326.t1 | SUPERFAMILY | SSF54665 | CO dehydrogenase molybdoprotein N-domain-like | 208 | 330 | 0.000 |
| 14 | g9326.t1 | SUPERFAMILY | SSF56003 | Molybdenum cofactor-binding domain | 327 | 736 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0046872 | metal ion binding | MF |
| GO:0050660 | flavin adenine dinucleotide binding | MF |
| GO:0055114 | NA | NA |
| GO:0071949 | FAD binding | MF |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed