Gene loci information

Transcript annotation

  • This transcript has been annotated as Serine protease snake.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g9355 g9355.t1 isoform g9355.t1 2201709 2205164
chr_1 g9355 g9355.t1 exon g9355.t1.exon1 2201709 2201808
chr_1 g9355 g9355.t1 cds g9355.t1.CDS1 2201709 2201808
chr_1 g9355 g9355.t1 exon g9355.t1.exon2 2202643 2202800
chr_1 g9355 g9355.t1 cds g9355.t1.CDS2 2202643 2202800
chr_1 g9355 g9355.t1 exon g9355.t1.exon3 2202898 2202982
chr_1 g9355 g9355.t1 cds g9355.t1.CDS3 2202898 2202982
chr_1 g9355 g9355.t1 exon g9355.t1.exon4 2203594 2203872
chr_1 g9355 g9355.t1 cds g9355.t1.CDS4 2203594 2203872
chr_1 g9355 g9355.t1 exon g9355.t1.exon5 2204402 2204481
chr_1 g9355 g9355.t1 cds g9355.t1.CDS5 2204402 2204481
chr_1 g9355 g9355.t1 exon g9355.t1.exon6 2204571 2204639
chr_1 g9355 g9355.t1 cds g9355.t1.CDS6 2204571 2204639
chr_1 g9355 g9355.t1 exon g9355.t1.exon7 2204787 2204798
chr_1 g9355 g9355.t1 cds g9355.t1.CDS7 2204787 2204798
chr_1 g9355 g9355.t1 exon g9355.t1.exon8 2204863 2204872
chr_1 g9355 g9355.t1 cds g9355.t1.CDS8 2204863 2204872
chr_1 g9355 g9355.t1 exon g9355.t1.exon9 2204944 2204957
chr_1 g9355 g9355.t1 cds g9355.t1.CDS9 2204944 2204957
chr_1 g9355 g9355.t1 exon g9355.t1.exon10 2205018 2205164
chr_1 g9355 g9355.t1 cds g9355.t1.CDS10 2205018 2205164
chr_1 g9355 g9355.t1 TSS g9355.t1 NA NA
chr_1 g9355 g9355.t1 TTS g9355.t1 NA NA

Sequences

>g9355.t1 Gene=g9355 Length=954
ATGATTCTGTGTTTATGGAATCTGACTTTTCAATTATTGCTAACAGTCGGCAATTTGCTA
CTGAAGAATTGTGATGCTGTTGGAGAGATTGCTTGTGAAAAATGTCAAGAGTATTCAAAG
TACGTATATGTGGATGAAGCAAGTCCTGTACTATCAGCTTCATATTCAGAATTGGATTCA
ATATCGAAATGTGGAATTGTAGAGACGCCATTAATCGTTGGCGGGCAACGAGTCAATGAA
ATTGAATTTCCTCATATGGCTGCCATCGGCTATAAATCGAATGAGGAAAATATTTCGTTC
AAATGTGGAGGCTCTCTTATATCTGAGCTTTACATTCTCACAGCTGCACATTGTGAATTG
GTCCATGAATATGGACCGCCTGTAGCTGTTAAGCTGGGAATAATTTATATTCATGATAGT
GGTCCGAATGCACAACTTATCGACATTGAGTCCTTTATCTCGCATCCGCAGTATCAGAGT
GCTGAGAAATATTTCGACATCGCGCTCATCAAATTAAAGTCATTTGTTAAATTTGATGAG
TATGTCAGGCCAGCGTGCGTTTGTCAACTAACGAGTGAATGGAACAAGGCTATCGCAGTA
GGCTTTGGAAAAACACAATATGAAAACGATAAAGGGAGTCCGCATCTTATGAAAGTCTTG
CTGAGTTATGTCGATAGAGCCACTTGCGTAGCAACTTATCAGTCTTATAAGCTGCTTAAA
AATGGAATAATTGATTCACAATTTTGTGCTGGTGAGAGAAAAGGAAATAAGGATTCTTGT
CAGGGTGACAGTGGTGGACCACTTCAGATTGTCATGTCAGAGCCATATTGCATGTACAAT
ATCATCGGAATTACATCGTTTGGAAAATTTTGTGGATTTGCTAACTCATATGGAGTTTAT
ACGAATGTAACGAGTTTTATTGATTTCATTGAAAGTATTGTATGGACTGAATAA

>g9355.t1 Gene=g9355 Length=317
MILCLWNLTFQLLLTVGNLLLKNCDAVGEIACEKCQEYSKYVYVDEASPVLSASYSELDS
ISKCGIVETPLIVGGQRVNEIEFPHMAAIGYKSNEENISFKCGGSLISELYILTAAHCEL
VHEYGPPVAVKLGIIYIHDSGPNAQLIDIESFISHPQYQSAEKYFDIALIKLKSFVKFDE
YVRPACVCQLTSEWNKAIAVGFGKTQYENDKGSPHLMKVLLSYVDRATCVATYQSYKLLK
NGIIDSQFCAGERKGNKDSCQGDSGGPLQIVMSEPYCMYNIIGITSFGKFCGFANSYGVY
TNVTSFIDFIESIVWTE

Protein features from InterProScan

Transcript Database ID Name Start End E.value
15 g9355.t1 CDD cd00190 Tryp_SPc 72 313 5.65024E-70
9 g9355.t1 Gene3D G3DSA:2.40.10.10 - 63 314 2.5E-66
2 g9355.t1 PANTHER PTHR24260 - 29 316 1.6E-70
3 g9355.t1 PANTHER PTHR24260:SF91 FI18411P1-RELATED 29 316 1.6E-70
4 g9355.t1 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 103 118 1.5E-13
6 g9355.t1 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 162 176 1.5E-13
5 g9355.t1 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 257 269 1.5E-13
1 g9355.t1 Pfam PF00089 Trypsin 72 310 1.1E-50
11 g9355.t1 Phobius SIGNAL_PEPTIDE Signal peptide region 1 26 -
12 g9355.t1 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide. 1 2 -
13 g9355.t1 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide. 3 14 -
14 g9355.t1 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide. 15 26 -
10 g9355.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 27 317 -
17 g9355.t1 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 113 118 -
18 g9355.t1 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 258 269 -
19 g9355.t1 ProSiteProfiles PS50240 Serine proteases, trypsin domain profile. 72 315 27.12
16 g9355.t1 SMART SM00020 trypsin_2 71 310 2.8E-63
7 g9355.t1 SUPERFAMILY SSF50494 Trypsin-like serine proteases 56 315 2.91E-70
8 g9355.t1 SignalP_EUK SignalP-noTM SignalP-noTM 1 26 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0004252 serine-type endopeptidase activity MF
GO:0006508 proteolysis BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed