General information for g9369.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Tuberin.
Parent gene
- The parent gene g9369 is located on chr_1: 2284631..2285851 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9369 | g9369.t2 | isoform | g9369.t2 | 2280679 | 2282076 |
| chr_1 | g9369 | g9369.t2 | exon | g9369.t2.exon1 | 2280679 | 2282076 |
| chr_1 | g9369 | g9369.t2 | cds | g9369.t2.CDS1 | 2280681 | 2282054 |
| chr_1 | g9369 | g9369.t2 | TSS | g9369.t2 | NA | NA |
| chr_1 | g9369 | g9369.t2 | TTS | g9369.t2 | NA | NA |
Sequences
>g9369.t2 Gene=g9369 Length=1398
GATTCTCAAATCGGAAGTTCGAATGGATGGTTGTTTGAGCATTTGTGTACAAGCATTCAC
TATTTTATTGATGGAACGCTGTGATATTTTTGAAAGACAACTTGCTGATATTGTTCTAGC
AATTTCAAAAGTTTCTGACACAATGCACGTTGCAATTCCGATTCTAGAATTCATATCAAC
CATCACACATTTGCCGTATTCATTTACAAATTTGAATCAAAAGCAATTCTCGTATGTATT
TGCAACGTGCCTTCCCTATACTAGTCCCGCTCGCTACGATCATTATGTGGTGTCATTAGC
ACATCATATTATTGCAAGTTGGTTCCTAAAATCGCGTCTTCAATGGCGTAAGCAATATGC
GGATTATATTATAGAAGGTATTGCAAAGAATATTGATAAATCTATGCAAGATGCAAAGCA
ACTGCAACGACAAGTTCAAGATGATGCAAATAAGGGATTTAATTTAGTCAATGAAGATTC
TTCACTGAGAAAAAGGAGCTCAAGTTTGACAGAACAATCTAATCGCAGGAAGGAAATTAA
TAATCCACAACTCATGAAAATGAAAGCTCAAAGAGTCGCTTTACAAAATTTATCACCAAA
TTTTGATATGCATGGATTTCATATTGAATTAATAGAGACTTGTATTGATTTTATGGCTCG
TCATACTTATTCTCTTTCACTGGCATTACCCAGACGTTTGCCAAGTGCCAATTATCTTCT
TCGCGGTGGTGGTCAATCAAAAACGTGGATCTTGGGTCATGTTGTTATTACAGTTACTAC
AAATGCTTGTATGGATAATCACGATTATGCTCGTTGTTCTTGTTATTACTCTGATTGGGC
TGAAATAATTGTTCGACGACCAACTGGAATGCTTTCTTGGATGATGAAATTTCAAAATCA
AGTGGGAGCATTTGCAAATGAATTTTCATTTTATGATCTGAAAGGATTATTTTCTGATTA
TGAATTAGATTGTGATAATCCAAATGGTATATTAGTAAGAAAGAAAATTGATGAATCATA
TTCAGATGAAGCAGCATTATTGATGGAAAAATTATCTATAAATGATGAATTTGGAAAGAT
TCCATTACAATCTACTGCCAGTGACTCTTCCGTTTTGAATATTGTAACTCAACCAATTAA
TATACCAATAACAAAACCATCTGAATTAGAGCAAGGTGTTCCTGAAGATGATATTTCTTA
TGATGACGATGATCCTGATGATCCTAAAAGAAATCCAGTTCGAAGAGTCAATTCATCGCC
TGAAATGAGATCAAATTGGAAGCATTCGAAACAAACACAAGCTCGCAATGAAAAAGATAG
TAAATTAGGATCTAATTCTACAATCACAGATGAACAAGAGGACAAAAGTGTAATTGAATG
TAGTGAAGTGCAACAAAA
>g9369.t2 Gene=g9369 Length=458
MDGCLSICVQAFTILLMERCDIFERQLADIVLAISKVSDTMHVAIPILEFISTITHLPYS
FTNLNQKQFSYVFATCLPYTSPARYDHYVVSLAHHIIASWFLKSRLQWRKQYADYIIEGI
AKNIDKSMQDAKQLQRQVQDDANKGFNLVNEDSSLRKRSSSLTEQSNRRKEINNPQLMKM
KAQRVALQNLSPNFDMHGFHIELIETCIDFMARHTYSLSLALPRRLPSANYLLRGGGQSK
TWILGHVVITVTTNACMDNHDYARCSCYYSDWAEIIVRRPTGMLSWMMKFQNQVGAFANE
FSFYDLKGLFSDYELDCDNPNGILVRKKIDESYSDEAALLMEKLSINDEFGKIPLQSTAS
DSSVLNIVTQPINIPITKPSELEQGVPEDDISYDDDDPDDPKRNPVRRVNSSPEMRSNWK
HSKQTQARNEKDSKLGSNSTITDEQEDKSVIECSEVQQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g9369.t2 | Coils | Coil | Coil | 117 | 144 | - |
| 6 | g9369.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 156 | 175 | - |
| 8 | g9369.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 156 | 173 | - |
| 7 | g9369.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 392 | 458 | - |
| 2 | g9369.t2 | PANTHER | PTHR10063 | TUBERIN | 9 | 321 | 6.0E-24 |
| 3 | g9369.t2 | PANTHER | PTHR10063:SF0 | TUBERIN | 9 | 321 | 6.0E-24 |
| 4 | g9369.t2 | PRINTS | PR01431 | Tuberin signature | 42 | 62 | 2.3E-10 |
| 5 | g9369.t2 | PRINTS | PR01431 | Tuberin signature | 88 | 108 | 2.3E-10 |
| 1 | g9369.t2 | Pfam | PF03542 | Tuberin | 3 | 107 | 6.7E-42 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0032007 | negative regulation of TOR signaling | BP |
| GO:0033596 | TSC1-TSC2 complex | CC |
| GO:0005634 | nucleus | CC |
| GO:0043547 | positive regulation of GTPase activity | BP |
| GO:0005096 | GTPase activator activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
