Gene loci information

Transcript annotation

  • This transcript has been annotated as Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g9425 g9425.t14 TSS g9425.t14 2855702 2855702
chr_1 g9425 g9425.t14 isoform g9425.t14 2855799 2857514
chr_1 g9425 g9425.t14 exon g9425.t14.exon1 2855799 2856523
chr_1 g9425 g9425.t14 exon g9425.t14.exon2 2856653 2856803
chr_1 g9425 g9425.t14 cds g9425.t14.CDS1 2856754 2856803
chr_1 g9425 g9425.t14 exon g9425.t14.exon3 2856862 2857316
chr_1 g9425 g9425.t14 cds g9425.t14.CDS2 2856862 2857316
chr_1 g9425 g9425.t14 exon g9425.t14.exon4 2857456 2857514
chr_1 g9425 g9425.t14 cds g9425.t14.CDS3 2857456 2857514
chr_1 g9425 g9425.t14 TTS g9425.t14 2857573 2857573

Sequences

>g9425.t14 Gene=g9425 Length=1390
ATGATGCAAAATATTTCGAGAAATACATCAAAGTTATTATGGAGAAATGCTGGAATAGTA
AATACCAACGTCCTTATATTGTGTGTCAACAAGAATAATTAATTTTAAAAATTTTCTTTA
TAGAAAAATTATGCAACAGAGGCAACTTTTGAAGTCAATCGGGTGAGTGCAATATTTTCA
TTGTTGTTGTTGTCATTTAAATTTAAACTGCACATGTGCAATAACTAATACACATTCAAT
CACATAGATTCTCAACTTTTTGGCAAATTTCTCTCTTTACTCTCAACAGCTGATTATTTA
TTTACTTTTACTTTCATTTTTTTAGCCATATAAACTCCATCGTCTCGATTCTGGTCCATC
AACAACTGTTTCAGTAACTCGTGATGAAGCACTTGATATGTATAGAAAAATGCAATCAAT
TCGTCGCCTTGAGACAAGTGCCGGTAACTTGTATAAGGAAAAGATTGTTCGTGGATTCTG
TCATTTGTATTCTGGTCAAGAGGCTGTTGCTGTTGGAATGAAAGCTTCGATGCGCGAACA
AGACAATATTATTTCTGCATATCGTGTTCATGGTTGGACACATTTAATGGGAGTGTCAGT
AGCTGGCGTCTTGTCAGAATTGACTGGTAAAAAAGGTGGTTGTGCTCGTGGAAAAGGCGG
TTCAATGCATATGGTAATAAAATTAATTTACTAAAATTTCTTTAGTCATAATCAATTAAT
TTGCAGTGTTGCTTTTGCATGCAAATACAAAAACAATGGAGGTGTATGCTTGTCACTTTA
CGGAGATGGTGCATCAAATCAAGGACAAGTTTTTGAAGCTTACAATATGGCTTATCTCTG
GAAATTACCATGCATTTTCATTTGTGAAAACAATGGATATGGCATGGGAACAAGTGCTGA
ACGTTCATCAAGCAATACAGAATATTACAAACGTGGTGATGTTTTGCCTGGCTTATGGAT
TGATGGTATGGATGTATTAGCTGTTAAAGAAGGAACACGATTTGCAATTGATTATGTATT
AAAAAATGGTCCTATTGTGATTGAAGCTGCTACTTATCGTTATTCAGGCCATAGCATGTC
TGATCCAGGCACAAGCTACAGATCACGTGATGAAATTCAAGAAGTTCGTCAAAAACGTGA
TCCAATCACTTCATTTAAAGAGAGAATGCTTGAGACTGGTTTAGCAACAGAAGCTGATAT
TAAGAAAATTGATAGTGAAGTTAAGAAAGAAGTTGATGCAGCAACAGCACTTGCAAAGAG
TGATACTGAAATCCCTGTATCAGAACTCACATGCGATATTTACTCCATGAATCAAGAGGG
TGATGTGCATGGATTGACACCAGACAAAAAGTTAAAGCACACAACACTCAAGACTGCTGT
AAATCTTTAA

>g9425.t14 Gene=g9425 Length=187
MAYLWKLPCIFICENNGYGMGTSAERSSSNTEYYKRGDVLPGLWIDGMDVLAVKEGTRFA
IDYVLKNGPIVIEAATYRYSGHSMSDPGTSYRSRDEIQEVRQKRDPITSFKERMLETGLA
TEADIKKIDSEVKKEVDAATALAKSDTEIPVSELTCDIYSMNQEGDVHGLTPDKKLKHTT
LKTAVNL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g9425.t14 Gene3D G3DSA:3.40.50.970 - 1 180 0
2 g9425.t14 PANTHER PTHR11516:SF55 PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA 1 181 0
3 g9425.t14 PANTHER PTHR11516 PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR 1 181 0
1 g9425.t14 Pfam PF00676 Dehydrogenase E1 component 1 149 0
4 g9425.t14 SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) 1 160 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values