Gene loci information

Transcript annotation

  • This transcript has been annotated as Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g9425 g9425.t15 TSS g9425.t15 2855702 2855702
chr_1 g9425 g9425.t15 isoform g9425.t15 2856524 2857514
chr_1 g9425 g9425.t15 exon g9425.t15.exon1 2856524 2856803
chr_1 g9425 g9425.t15 cds g9425.t15.CDS1 2856754 2856803
chr_1 g9425 g9425.t15 exon g9425.t15.exon2 2856862 2857316
chr_1 g9425 g9425.t15 cds g9425.t15.CDS2 2856862 2857316
chr_1 g9425 g9425.t15 exon g9425.t15.exon3 2857456 2857514
chr_1 g9425 g9425.t15 cds g9425.t15.CDS3 2857456 2857514
chr_1 g9425 g9425.t15 TTS g9425.t15 2857573 2857573

Sequences

>g9425.t15 Gene=g9425 Length=794
GTATTCAAAAAATTTCTATGGAGGAAACGGAATTGTTGGCGCTCAAGTGCCACTTGGAGC
AGGTTATAATTTGACTACTAAATATCTTCATATTTTAATAAATATTTTTGATTCTATAAA
ATATTTCAGGTGTTGCTTTTGCATGCAAATACAAAAACAATGGAGGTGTATGCTTGTCAC
TTTACGGAGATGGTGCATCAAATCAAGGACAAGTTTTTGAAGCTTACAATATGGCTTATC
TCTGGAAATTACCATGCATTTTCATTTGTGAAAACAATGGATATGGCATGGGAACAAGTG
CTGAACGTTCATCAAGCAATACAGAATATTACAAACGTGGTGATGTTTTGCCTGGCTTAT
GGATTGATGGTATGGATGTATTAGCTGTTAAAGAAGGAACACGATTTGCAATTGATTATG
TATTAAAAAATGGTCCTATTGTGATTGAAGCTGCTACTTATCGTTATTCAGGCCATAGCA
TGTCTGATCCAGGCACAAGCTACAGATCACGTGATGAAATTCAAGAAGTTCGTCAAAAAC
GTGATCCAATCACTTCATTTAAAGAGAGAATGCTTGAGACTGGTTTAGCAACAGAAGCTG
ATATTAAGAAAATTGATAGTGAAGTTAAGAAAGAAGTTGATGCAGCAACAGCACTTGCAA
AGAGTGATACTGAAATCCCTGTATCAGAACTCACATGCGATATTTACTCCATGAATCAAG
AGGGTGATGTGCATGGATTGACACCAGACAAAAAGTTAAAGCACACAACACTCAAGACTG
CTGTAAATCTTTAA

>g9425.t15 Gene=g9425 Length=187
MAYLWKLPCIFICENNGYGMGTSAERSSSNTEYYKRGDVLPGLWIDGMDVLAVKEGTRFA
IDYVLKNGPIVIEAATYRYSGHSMSDPGTSYRSRDEIQEVRQKRDPITSFKERMLETGLA
TEADIKKIDSEVKKEVDAATALAKSDTEIPVSELTCDIYSMNQEGDVHGLTPDKKLKHTT
LKTAVNL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g9425.t15 Gene3D G3DSA:3.40.50.970 - 1 180 0
2 g9425.t15 PANTHER PTHR11516:SF55 PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA 1 181 0
3 g9425.t15 PANTHER PTHR11516 PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR 1 181 0
1 g9425.t15 Pfam PF00676 Dehydrogenase E1 component 1 149 0
4 g9425.t15 SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) 1 160 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values