General information for g9569.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as 26S proteasome regulatory subunit 7.
Parent gene
- The parent gene g9569 is located on chr_1: 4075062..4075622 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9569 | g9569.t1 | TTS | g9569.t1 | 4074061 | 4074061 |
| chr_1 | g9569 | g9569.t1 | isoform | g9569.t1 | 4074131 | 4075622 |
| chr_1 | g9569 | g9569.t1 | exon | g9569.t1.exon1 | 4074131 | 4074766 |
| chr_1 | g9569 | g9569.t1 | cds | g9569.t1.CDS1 | 4074131 | 4074766 |
| chr_1 | g9569 | g9569.t1 | exon | g9569.t1.exon2 | 4074828 | 4075251 |
| chr_1 | g9569 | g9569.t1 | cds | g9569.t1.CDS2 | 4074828 | 4075251 |
| chr_1 | g9569 | g9569.t1 | exon | g9569.t1.exon3 | 4075308 | 4075479 |
| chr_1 | g9569 | g9569.t1 | cds | g9569.t1.CDS3 | 4075308 | 4075479 |
| chr_1 | g9569 | g9569.t1 | exon | g9569.t1.exon4 | 4075547 | 4075622 |
| chr_1 | g9569 | g9569.t1 | cds | g9569.t1.CDS4 | 4075547 | 4075622 |
| chr_1 | g9569 | g9569.t1 | TSS | g9569.t1 | 4075709 | 4075709 |
Sequences
>g9569.t1 Gene=g9569 Length=1308
ATGCCGGATCATTTAGGTGATGATATGCGTAAGGTGAAAGTGGACGATAAGGAAAAAGAT
GAGCCAGTAATAAAAGATCTCGATGAAGGAGATATTGAGCTTTTAAAGACTTATGGACAG
GGACAGTATCATAAAAGTATCAAACAAATTGAAGATGATATCCAAAAGGCAATTAAACAA
GTTAATGAACTCACTGGAATCAAAGAAAGTGACACTGGTCTTGCTCCTCCAGCTTTGTGG
GATTTAGCTGCTGATAAACAAACACTTCAGAATGAGCAACCATTACAAGTAGCTCGCTGT
ACAAAAATTATTAATGCGGATTCGGATGATCCTAAATATATCATCAATGTTAAGCAATTT
GCAAAATTTGTAGTTGATCTTGCTGACTCAGTTGCACCAACAGATATTGAAGAAGGAATG
CGTGTGGGTGTTGATAGAAATAAATATCAAATTCATATTCCATTGCCTCCGAAAATTGAT
CCAACTGTTACAATGATGCAAGTTGAAGATAAACCAGATGTCACTTACTCAGATGTTGGA
GGATGTAAAGAACAGATTGAGAAACTTAGAGAAGTTGTTGAAACACCTCTCTTGCATCCA
GAAAAGTTTGTCACACTCGGTATTGAACCACCAAAAGGCGTGCTTCTTTTTGGACCACCT
GGAACTGGCAAGACACTATGTGCAAGAGCAGTTGCAAATCGTACTGATGCTTGTTTTATT
CGTGTAATTGGATCTGAGTTGGTTCAGAAATATGTCGGTGAAGGAGCGAGAATGGTTCGC
GAATTATTTGAAATGGCACGCAGTAAAAAAGCTTGTCTCATCTTTTTCGATGAAATTGAT
GCTATTGGTGGTGCACGTTTTGACGATGGTGCAGGAGGAGATAATGAAGTTCAAAGAACT
ATGTTGGAACTTATTAATCAACTTGATGGTTTTGATCCTCGTGGTAATATCAAAGTTTTG
ATGGCTACAAATCGTCCTGATACTTTAGATCCTGCATTAATGCGTCCTGGTCGTCTCGAT
AGAAAAGTTGAATTTGGCTTACCTGACCTCGAAGGAAGAGCTCACATTTTTAAAATTCAT
GCTCGTTCAATGTCTGTTGAGCGTGATATTCGCTTTGAATTGCTTGCTCGATTATGTCCT
AATTCAACTGGTGCTGAAATTCGATCAGTTTGCACAGAAGCTGGCATGTTTGCTATTCGT
GCACGACGTAAAGTTGCAACAGAGAAAGATTTCCTTGAAGCTGTGAACAAAGTCATCAAG
AGCTACGCCAAATTCTCAGCTACTCCACGTTACATGACTTACAATTAA
>g9569.t1 Gene=g9569 Length=435
MPDHLGDDMRKVKVDDKEKDEPVIKDLDEGDIELLKTYGQGQYHKSIKQIEDDIQKAIKQ
VNELTGIKESDTGLAPPALWDLAADKQTLQNEQPLQVARCTKIINADSDDPKYIINVKQF
AKFVVDLADSVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEDKPDVTYSDVG
GCKEQIEKLREVVETPLLHPEKFVTLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFI
RVIGSELVQKYVGEGARMVRELFEMARSKKACLIFFDEIDAIGGARFDDGAGGDNEVQRT
MLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKVEFGLPDLEGRAHIFKIH
ARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKDFLEAVNKVIK
SYAKFSATPRYMTYN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g9569.t1 | CDD | cd00009 | AAA | 180 | 347 | 8.91878E-27 |
| 9 | g9569.t1 | Coils | Coil | Coil | 47 | 67 | - |
| 8 | g9569.t1 | Gene3D | G3DSA:2.40.50.140 | - | 40 | 166 | 6.0E-25 |
| 6 | g9569.t1 | Gene3D | G3DSA:3.40.50.300 | - | 167 | 346 | 1.8E-65 |
| 7 | g9569.t1 | Gene3D | G3DSA:1.10.8.60 | - | 348 | 420 | 8.9E-23 |
| 3 | g9569.t1 | PANTHER | PTHR23073 | 26S PROTEASOME REGULATORY SUBUNIT | 18 | 433 | 2.5E-252 |
| 4 | g9569.t1 | PANTHER | PTHR23073:SF13 | 26S PROTEASOME REGULATORY SUBUNIT 7 | 18 | 433 | 2.5E-252 |
| 1 | g9569.t1 | Pfam | PF00004 | ATPase family associated with various cellular activities (AAA) | 214 | 346 | 1.2E-39 |
| 2 | g9569.t1 | Pfam | PF17862 | AAA+ lid domain | 369 | 413 | 1.1E-8 |
| 11 | g9569.t1 | ProSitePatterns | PS00674 | AAA-protein family signature. | 317 | 335 | - |
| 12 | g9569.t1 | SMART | SM00382 | AAA_5 | 210 | 349 | 9.5E-23 |
| 5 | g9569.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 172 | 422 | 4.53E-68 |
| 13 | g9569.t1 | TIGRFAM | TIGR01242 | 26Sp45: 26S proteasome subunit P45 family | 107 | 418 | 7.9E-123 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0036402 | proteasome-activating activity | MF |
| GO:0030163 | protein catabolic process | BP |
| GO:0005737 | cytoplasm | CC |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
- This transcript has been annotated with K03061 (26S proteasome regulatory subunit T1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
