Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Proteasome subunit alpha type-1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g9583 g9583.t1 isoform g9583.t1 4141746 4142444
chr_1 g9583 g9583.t1 exon g9583.t1.exon1 4141746 4142065
chr_1 g9583 g9583.t1 cds g9583.t1.CDS1 4141746 4142065
chr_1 g9583 g9583.t1 exon g9583.t1.exon2 4142124 4142353
chr_1 g9583 g9583.t1 cds g9583.t1.CDS2 4142124 4142353
chr_1 g9583 g9583.t1 exon g9583.t1.exon3 4142410 4142444
chr_1 g9583 g9583.t1 cds g9583.t1.CDS3 4142410 4142444
chr_1 g9583 g9583.t1 TSS g9583.t1 NA NA
chr_1 g9583 g9583.t1 TTS g9583.t1 NA NA

Sequences

>g9583.t1 Gene=g9583 Length=585
ATGACTGGAATTACTACTGATACTCGTGTTCTATGTCACTATATGCGTCAGGAATGCATA
AATCATAAGCATTCTTATGATAGAAATCATCCAGTTGGTCGCTTGATTAATTTATTAAAA
CTTAAGATGCAGGTGTGCACTCAGCGTTATGACCGTCGTCCTTATGGTGTTGGTTTGCTT
GTTGCTGGTTACGATGATCAAGGACCACATATTTATCAGACTTGTCCAAGTGCAAACTTT
TACGATTGCAAAGCAATGGCAATTGATTGCAATCTTTCTGATTTGATTAATCATGGTGTT
CGTGCTTTGACGGGTACATTACCAAACGAAACTAAATTGAACAATAAAAACTTGTCAATT
TGTGTTGTTGGAAAGAATTATAAATTCCATTGCTTAGACGAAAACGAGTTGGAGAAATAT
ATTATTGCTGAAATCGTTGGAACTCAACCTACTTCTTCTGCTAGTGATTCTTCAGAGGTA
GGCGTTGGAAGAACCGAAAGACATGGCGAAGAACAATCGTCAACTTTAAACCCACAAGAT
CCAACTCCAGTAGAATCTGCTACTGAAGATCGAAGAATGCAATAA

>g9583.t1 Gene=g9583 Length=194
MTGITTDTRVLCHYMRQECINHKHSYDRNHPVGRLINLLKLKMQVCTQRYDRRPYGVGLL
VAGYDDQGPHIYQTCPSANFYDCKAMAIDCNLSDLINHGVRALTGTLPNETKLNNKNLSI
CVVGKNYKFHCLDENELEKYIIAEIVGTQPTSSASDSSEVGVGRTERHGEEQSSTLNPQD
PTPVESATEDRRMQ

Protein features from InterProScan

Transcript Database ID Name Start End E.value
6 g9583.t1 Gene3D G3DSA:3.60.20.10 Glutamine Phosphoribosylpyrophosphate 1 145 3.0E-36
5 g9583.t1 MobiDBLite mobidb-lite consensus disorder prediction 151 194 -
2 g9583.t1 PANTHER PTHR11599:SF12 PROTEASOME SUBUNIT ALPHA TYPE-1 2 168 9.8E-42
3 g9583.t1 PANTHER PTHR11599 PROTEASOME SUBUNIT ALPHA/BETA 2 168 9.8E-42
1 g9583.t1 Pfam PF00227 Proteasome subunit 1 88 6.3E-25
4 g9583.t1 SUPERFAMILY SSF56235 N-terminal nucleophile aminohydrolases (Ntn hydrolases) 1 141 1.61E-34

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0019773 proteasome core complex, alpha-subunit complex CC
GO:0051603 proteolysis involved in cellular protein catabolic process BP
GO:0005839 proteasome core complex CC

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values