General information for g9594.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Acetyl-CoA acetyltransferase.
Parent gene
- The parent gene g9594 is located on chr_1: 4187512..4189260 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9594 | g9594.t1 | TTS | g9594.t1 | 4187322 | 4187322 |
| chr_1 | g9594 | g9594.t1 | isoform | g9594.t1 | 4187512 | 4188754 |
| chr_1 | g9594 | g9594.t1 | exon | g9594.t1.exon1 | 4187512 | 4188644 |
| chr_1 | g9594 | g9594.t1 | cds | g9594.t1.CDS1 | 4187512 | 4188644 |
| chr_1 | g9594 | g9594.t1 | exon | g9594.t1.exon2 | 4188703 | 4188754 |
| chr_1 | g9594 | g9594.t1 | cds | g9594.t1.CDS2 | 4188703 | 4188754 |
| chr_1 | g9594 | g9594.t1 | TSS | g9594.t1 | 4189274 | 4189274 |
Sequences
>g9594.t1 Gene=g9594 Length=1185
ATGACCTCATTACCTGAAGTATACATTGTTTCAGCAGCAAGAACTCCAATTGGAAGTTTC
CAAGGTGCATTCAATAATCTTCCAGCACATGATTTAGGCGCTGTCGTTATTAAAGAAGTA
GTTCAACGTGCAAGTTTATCACCATCAGATGTAAATGAAGTTATTTTAGGACAGGCACTT
CAAGCAGCTGCTGGTCAAAATCCCGCAAGACAGGCATCACTCAAAGCTGGTTTGCCAAAT
GATATTCCTGCTTATGGAATCAATATGCTTTGTGGTTCTGGTTTAAAATCAGTAGCACTT
GGTTTTCAAGCAATTCGCAATGGTGACTCGAATATTGTTGTTTGTGGAGGACAAGAAAGC
ATGACACGTGCACCGCATGCAATACATTTAAGAAGTGGTACAAAAATGGGTACTGCATCT
ATGGTTGACACAATGATTCAAGATGGTCTAACAGATGCAATGCATTCCATTCATATGGGA
GAAACTGCTGAGAATCTCGCAAAAGAATTCTCAGTCACAAGACAAGAGCAAGATGCATTT
GCAGCCAAATCTCAACAACTCGCTGATACAGCTCAAAAATCAGGCTGGTTTGATGAGGAA
ATTGTGCCTGTTGTTGTTGCTGGCCGTAAAGAATCAGTTACTATTTCAAAAGATGAATAT
TTGAAACCTGGAACTAGTGTTGAAGGATTATCAAAATTAAGAGCATGCTTCATCAAAGAT
GGAACTGTAACGCCAGGAAATGCTTCAGGTGTCAATGATTCTGCAGCTGCAGTTTTATTA
GCTTCAGCTGATGAAGTAACTAAAAGAAATCTCAAACCATTAGCAAAAATTGTTGCATTT
AGTCAAGTTGGATGTGATCCAAAAATTATGGGTATTGGACCGAAATATGCAGTTCCCGAA
GTTATAAAAAAAGCAGGTTGGACTCTCGATGAAGTAGATTTATTTGAGTTAAATGAAGCA
TTTGCAGCACAAGCAATTTCAGTAAATCGTGGATTGAATATTAATGAAGCAAAAGTTAAT
ATAAATGGTGGAGCAATTGCACTTGGTCATCCGATCGGTGCTAGTGGTGCTCGAGTTTTA
GTGACATTAATTTATGCTCTCAAACGTATTGGAAAGAAACGTGGAGTAGCGAGTTTATGC
GTTGGTGGTGGAATGGGAGTTGCGATGGCAATAGAAATGGTTTAA
>g9594.t1 Gene=g9594 Length=394
MTSLPEVYIVSAARTPIGSFQGAFNNLPAHDLGAVVIKEVVQRASLSPSDVNEVILGQAL
QAAAGQNPARQASLKAGLPNDIPAYGINMLCGSGLKSVALGFQAIRNGDSNIVVCGGQES
MTRAPHAIHLRSGTKMGTASMVDTMIQDGLTDAMHSIHMGETAENLAKEFSVTRQEQDAF
AAKSQQLADTAQKSGWFDEEIVPVVVAGRKESVTISKDEYLKPGTSVEGLSKLRACFIKD
GTVTPGNASGVNDSAAAVLLASADEVTKRNLKPLAKIVAFSQVGCDPKIMGIGPKYAVPE
VIKKAGWTLDEVDLFELNEAFAAQAISVNRGLNINEAKVNINGGAIALGHPIGASGARVL
VTLIYALKRIGKKRGVASLCVGGGMGVAMAIEMV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g9594.t1 | CDD | cd00751 | thiolase | 8 | 392 | 0.0 |
| 8 | g9594.t1 | Gene3D | G3DSA:3.40.47.10 | - | 8 | 277 | 2.5E-152 |
| 7 | g9594.t1 | Gene3D | G3DSA:3.40.47.10 | - | 129 | 391 | 2.5E-152 |
| 3 | g9594.t1 | PANTHER | PTHR18919:SF144 | ACETYL-COA ACETYLTRANSFERASE | 6 | 393 | 2.0E-157 |
| 4 | g9594.t1 | PANTHER | PTHR18919 | ACETYL-COA C-ACYLTRANSFERASE | 6 | 393 | 2.0E-157 |
| 9 | g9594.t1 | PIRSF | PIRSF000429 | Ac-CoA_Ac_transf | 1 | 394 | 1.0E-125 |
| 2 | g9594.t1 | Pfam | PF00108 | Thiolase, N-terminal domain | 7 | 263 | 1.6E-97 |
| 1 | g9594.t1 | Pfam | PF02803 | Thiolase, C-terminal domain | 271 | 392 | 1.6E-50 |
| 11 | g9594.t1 | ProSitePatterns | PS00098 | Thiolases acyl-enzyme intermediate signature. | 87 | 105 | - |
| 13 | g9594.t1 | ProSitePatterns | PS00737 | Thiolases signature 2. | 340 | 356 | - |
| 12 | g9594.t1 | ProSitePatterns | PS00099 | Thiolases active site. | 375 | 388 | - |
| 6 | g9594.t1 | SUPERFAMILY | SSF53901 | Thiolase-like | 6 | 268 | 2.07E-83 |
| 5 | g9594.t1 | SUPERFAMILY | SSF53901 | Thiolase-like | 272 | 393 | 6.08E-43 |
| 14 | g9594.t1 | TIGRFAM | TIGR01930 | AcCoA-C-Actrans: acetyl-CoA C-acyltransferase | 9 | 392 | 1.8E-140 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016746 | acyltransferase activity | MF |
| GO:0016747 | acyltransferase activity, transferring groups other than amino-acyl groups | MF |
KEGG
Orthology
- This transcript has been annotated with K00626 (acetyl-CoA C-acetyltransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
