Gene loci information

Transcript annotation

  • This transcript has been annotated as Acetyl-CoA acetyltransferase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g9594 g9594.t3 TTS g9594.t3 4187322 4187322
chr_1 g9594 g9594.t3 isoform g9594.t3 4187512 4189260
chr_1 g9594 g9594.t3 exon g9594.t3.exon1 4187512 4188644
chr_1 g9594 g9594.t3 cds g9594.t3.CDS1 4187512 4188432
chr_1 g9594 g9594.t3 exon g9594.t3.exon2 4188699 4188874
chr_1 g9594 g9594.t3 exon g9594.t3.exon3 4189242 4189260
chr_1 g9594 g9594.t3 TSS g9594.t3 4189274 4189274

Sequences

>g9594.t3 Gene=g9594 Length=1328
ATATTGAATAGTAAAATAGGAGGAAGAGAGCATCTTCGAGAGCAGACCGGTTTTATTTTA
GATTCTCTTAATAGACTGACACGTTGTCACATAGTTTCTATTCTTTTTTCTTAACAAGCT
TCACAATAATTTGTTAATTATGACCTCATTACCTGAAGTATACATTGTTTCAGCAGCAAG
AACTCCAATTGGTATGAAGTTTCCAAGGTGCATTCAATAATCTTCCAGCACATGATTTAG
GCGCTGTCGTTATTAAAGAAGTAGTTCAACGTGCAAGTTTATCACCATCAGATGTAAATG
AAGTTATTTTAGGACAGGCACTTCAAGCAGCTGCTGGTCAAAATCCCGCAAGACAGGCAT
CACTCAAAGCTGGTTTGCCAAATGATATTCCTGCTTATGGAATCAATATGCTTTGTGGTT
CTGGTTTAAAATCAGTAGCACTTGGTTTTCAAGCAATTCGCAATGGTGACTCGAATATTG
TTGTTTGTGGAGGACAAGAAAGCATGACACGTGCACCGCATGCAATACATTTAAGAAGTG
GTACAAAAATGGGTACTGCATCTATGGTTGACACAATGATTCAAGATGGTCTAACAGATG
CAATGCATTCCATTCATATGGGAGAAACTGCTGAGAATCTCGCAAAAGAATTCTCAGTCA
CAAGACAAGAGCAAGATGCATTTGCAGCCAAATCTCAACAACTCGCTGATACAGCTCAAA
AATCAGGCTGGTTTGATGAGGAAATTGTGCCTGTTGTTGTTGCTGGCCGTAAAGAATCAG
TTACTATTTCAAAAGATGAATATTTGAAACCTGGAACTAGTGTTGAAGGATTATCAAAAT
TAAGAGCATGCTTCATCAAAGATGGAACTGTAACGCCAGGAAATGCTTCAGGTGTCAATG
ATTCTGCAGCTGCAGTTTTATTAGCTTCAGCTGATGAAGTAACTAAAAGAAATCTCAAAC
CATTAGCAAAAATTGTTGCATTTAGTCAAGTTGGATGTGATCCAAAAATTATGGGTATTG
GACCGAAATATGCAGTTCCCGAAGTTATAAAAAAAGCAGGTTGGACTCTCGATGAAGTAG
ATTTATTTGAGTTAAATGAAGCATTTGCAGCACAAGCAATTTCAGTAAATCGTGGATTGA
ATATTAATGAAGCAAAAGTTAATATAAATGGTGGAGCAATTGCACTTGGTCATCCGATCG
GTGCTAGTGGTGCTCGAGTTTTAGTGACATTAATTTATGCTCTCAAACGTATTGGAAAGA
AACGTGGAGTAGCGAGTTTATGCGTTGGTGGTGGAATGGGAGTTGCGATGGCAATAGAAA
TGGTTTAA

>g9594.t3 Gene=g9594 Length=306
MLCGSGLKSVALGFQAIRNGDSNIVVCGGQESMTRAPHAIHLRSGTKMGTASMVDTMIQD
GLTDAMHSIHMGETAENLAKEFSVTRQEQDAFAAKSQQLADTAQKSGWFDEEIVPVVVAG
RKESVTISKDEYLKPGTSVEGLSKLRACFIKDGTVTPGNASGVNDSAAAVLLASADEVTK
RNLKPLAKIVAFSQVGCDPKIMGIGPKYAVPEVIKKAGWTLDEVDLFELNEAFAAQAISV
NRGLNINEAKVNINGGAIALGHPIGASGARVLVTLIYALKRIGKKRGVASLCVGGGMGVA
MAIEMV

Protein features from InterProScan

Transcript Database ID Name Start End E.value
11 g9594.t3 CDD cd00751 thiolase 1 304 1.04253E-153
9 g9594.t3 Gene3D G3DSA:3.40.47.10 - 1 306 5.9E-112
3 g9594.t3 PANTHER PTHR18919:SF144 ACETYL-COA ACETYLTRANSFERASE 1 305 1.1E-120
4 g9594.t3 PANTHER PTHR18919 ACETYL-COA C-ACYLTRANSFERASE 1 305 1.1E-120
2 g9594.t3 Pfam PF00108 Thiolase, N-terminal domain 2 175 5.2E-64
1 g9594.t3 Pfam PF02803 Thiolase, C-terminal domain 183 304 9.3E-51
8 g9594.t3 ProSitePatterns PS00737 Thiolases signature 2. 252 268 -
7 g9594.t3 ProSitePatterns PS00099 Thiolases active site. 287 300 -
5 g9594.t3 SUPERFAMILY SSF53901 Thiolase-like 2 180 4.66E-53
6 g9594.t3 SUPERFAMILY SSF53901 Thiolase-like 184 305 9.46E-43
10 g9594.t3 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 1 304 4.7E-111

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016746 acyltransferase activity MF
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values