General information for g9600.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Atrial natriuretic peptide receptor 1.
Parent gene
- The parent gene g9600 is located on chr_1: 4231817..4233282 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9600 | g9600.t1 | isoform | g9600.t1 | 4231817 | 4233282 |
| chr_1 | g9600 | g9600.t1 | exon | g9600.t1.exon1 | 4231817 | 4231896 |
| chr_1 | g9600 | g9600.t1 | cds | g9600.t1.CDS1 | 4231817 | 4231896 |
| chr_1 | g9600 | g9600.t1 | exon | g9600.t1.exon2 | 4231958 | 4232193 |
| chr_1 | g9600 | g9600.t1 | cds | g9600.t1.CDS2 | 4231958 | 4232193 |
| chr_1 | g9600 | g9600.t1 | exon | g9600.t1.exon3 | 4232248 | 4232381 |
| chr_1 | g9600 | g9600.t1 | cds | g9600.t1.CDS3 | 4232248 | 4232381 |
| chr_1 | g9600 | g9600.t1 | exon | g9600.t1.exon4 | 4232457 | 4232619 |
| chr_1 | g9600 | g9600.t1 | cds | g9600.t1.CDS4 | 4232457 | 4232619 |
| chr_1 | g9600 | g9600.t1 | exon | g9600.t1.exon5 | 4232690 | 4233282 |
| chr_1 | g9600 | g9600.t1 | cds | g9600.t1.CDS5 | 4232690 | 4233282 |
| chr_1 | g9600 | g9600.t1 | TTS | g9600.t1 | 4233371 | 4233371 |
| chr_1 | g9600 | g9600.t1 | TSS | g9600.t1 | NA | NA |
Sequences
>g9600.t1 Gene=g9600 Length=1206
ATGATTAGTTGTTGGGCTGAAGATCCATTGGATAGACCTGATTTCTCAGCTATAAAATCA
TCAATTAGAAAAATTAACAAAGAAAATGAGAGTGGAAATATTTTAGATAATTTACTTAAA
CGTATGGAGCACTATGCACAAAATCTCGAGACTCTTGTCGATGAAAGAACGCGTGATTAT
TTAGAAGAAAAGAAAAAATGTGAAGCTTTACTTTATCAGCTTCTTCCAATACCTATTGCA
AATCAACTTATTGAGGGCAAGCCTGTAATTGCAGAAATGTATGATCAAGTTACTATTTAT
TTTTCCGATATTGTTGGTTTCACAGCAATTTCATCAGAATCAACACCAATGCAAGTAGTT
GATCTTTTGAATGATTTGTACACGTGTTTTGATAAAATTGTTGGACATTTCGATGTGTAT
AAAGTTGAAACCATAGGTGATGCCTACATGGTTGTTTCAGGTTTGCCTGTTCGCAATGGA
GATTTACATGCCCGTGAAATTGCACGAATGGCACTAGCATTGTTAGCAAAGGTTCACAAT
TTTAAAATAGCACATCGGCCGGATGAAAAGTTAAAACTTCGAATTGGTCTTCATAGCGGT
CCTTGCTGTGCCGGTGTGGTAGGCTTGAAAATGCCAAGATTTTGTCTTTTTGGTGACACG
GTCAATACAGCAAGTAGAATGGAATCGAATGGTGAAGCTTTAAAGATTCACATAAGTCAC
AGTACAAAAGAGATTTTGGATAGATTCAAGACATTTGATATCGTAGAAAGAGGCTATGTG
GCGATGAAAGGAAAAGGCGAAATGAGAACATATTGGTTGAATGGTGAAAAAACTATAGAT
GAACTGATGCTCCCAAAACTAACATCGCCACCATCATTACCATCAATCGAAGCAAATAAC
AATAACATTAATCATCATGACAAGGATGTAAAATTCACTGATACAAATCATGTTCCTGAA
GAGAAACCAAAGGCAGTTGCAGTAGTTATTCCACAACTGACTCCACAAAATTCATTTAAT
TCAAAGAAAAATGTAACAATTAATAATTCTAGTCTCCGTAATAACCTCAACAGTTATAGT
AGTCTCAAAGATTTATCACATCAACCATTATTGAATGGAAAGAAACCGACGCTGTTAAAA
AAGAAACAAATTAATTTCAATAATGAAAAGCTTCAACAGCCATTACTAATGAATTCGATT
AAGTGA
>g9600.t1 Gene=g9600 Length=401
MISCWAEDPLDRPDFSAIKSSIRKINKENESGNILDNLLKRMEHYAQNLETLVDERTRDY
LEEKKKCEALLYQLLPIPIANQLIEGKPVIAEMYDQVTIYFSDIVGFTAISSESTPMQVV
DLLNDLYTCFDKIVGHFDVYKVETIGDAYMVVSGLPVRNGDLHAREIARMALALLAKVHN
FKIAHRPDEKLKLRIGLHSGPCCAGVVGLKMPRFCLFGDTVNTASRMESNGEALKIHISH
STKEILDRFKTFDIVERGYVAMKGKGEMRTYWLNGEKTIDELMLPKLTSPPSLPSIEANN
NNINHHDKDVKFTDTNHVPEEKPKAVAVVIPQLTPQNSFNSKKNVTINNSSLRNNLNSYS
SLKDLSHQPLLNGKKPTLLKKKQINFNNEKLQQPLLMNSIK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g9600.t1 | CDD | cd07302 | CHD | 96 | 273 | 1.5546E-74 |
| 6 | g9600.t1 | Coils | Coil | Coil | 35 | 55 | - |
| 5 | g9600.t1 | Gene3D | G3DSA:3.30.70.1230 | Adenylyl Cyclase | 89 | 278 | 2.8E-77 |
| 2 | g9600.t1 | PANTHER | PTHR11920 | GUANYLYL CYCLASE | 1 | 278 | 3.4E-162 |
| 3 | g9600.t1 | PANTHER | PTHR11920:SF488 | GUANYLATE CYCLASE | 1 | 278 | 3.4E-162 |
| 1 | g9600.t1 | Pfam | PF00211 | Adenylate and Guanylate cyclase catalytic domain | 91 | 275 | 4.0E-69 |
| 8 | g9600.t1 | ProSitePatterns | PS00452 | Guanylate cyclase signature. | 205 | 228 | - |
| 10 | g9600.t1 | ProSiteProfiles | PS50125 | Guanylate cyclase domain profile. | 98 | 228 | 50.966 |
| 9 | g9600.t1 | SMART | SM00044 | cyc_6 | 62 | 256 | 1.3E-103 |
| 4 | g9600.t1 | SUPERFAMILY | SSF55073 | Nucleotide cyclase | 84 | 273 | 1.88E-66 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016849 | phosphorus-oxygen lyase activity | MF |
| GO:0009190 | cyclic nucleotide biosynthetic process | BP |
| GO:0035556 | intracellular signal transduction | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
