Gene loci information

Transcript annotation

  • This transcript has been annotated as Calcium/calmodulin-dependent protein kinase type II alpha chain.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g9683 g9683.t1 isoform g9683.t1 4608573 4609242
chr_1 g9683 g9683.t1 exon g9683.t1.exon1 4608573 4608855
chr_1 g9683 g9683.t1 cds g9683.t1.CDS1 4608573 4608855
chr_1 g9683 g9683.t1 exon g9683.t1.exon2 4608916 4609125
chr_1 g9683 g9683.t1 cds g9683.t1.CDS2 4608916 4609125
chr_1 g9683 g9683.t1 exon g9683.t1.exon3 4609181 4609242
chr_1 g9683 g9683.t1 cds g9683.t1.CDS3 4609181 4609242
chr_1 g9683 g9683.t1 TSS g9683.t1 NA NA
chr_1 g9683 g9683.t1 TTS g9683.t1 NA NA

Sequences

>g9683.t1 Gene=g9683 Length=555
ATGGCTATGCCAGTCTGTACACGCTTCTCCGATAATTATGATATAAAAGAGGAGTTAGGA
AAAGGAGCATTTTCCATAGTTAAGCGATGTGTTCAGAAATCAACTGGACTTGAATTTGCT
GCAAAAATCATCAATACTAAAAAGTTAACAGCAAGAGATTTTCAAAAATTGAAACGTGAA
GCGCGTGTTTGTCGTAAATTGCAACATCCAAATATTGTGAGACTGCATGACAGCATAAAT
GAAGCAGATTATCATTATCTTATTTTTGATCTTGTAACTGGTGGTGAATTATTTGAGGAT
ATTGTGGCACGTGAATTTTATTCAGAAGCAGATGCGTCACATTGTATTCAACAGATACTT
GAGTCAGTTCATCACTGTCATCAAAATGGTATCGTGCATAGGGATTTGAAACCTGAAAAT
TTACTTCTAGCTAGTAAGATGAAGGGTGCTGCAGTAAAGTTGGCCGATTTTGGACTTGCC
ATTGAAGTACAGGGTGATCAACAAGCTTGGTTTGGTTTTGCAGGCACACCAGGCTACTTG
TCACCCGAAGTTTAA

>g9683.t1 Gene=g9683 Length=184
MAMPVCTRFSDNYDIKEELGKGAFSIVKRCVQKSTGLEFAAKIINTKKLTARDFQKLKRE
ARVCRKLQHPNIVRLHDSINEADYHYLIFDLVTGGELFEDIVAREFYSEADASHCIQQIL
ESVHHCHQNGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL
SPEV

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g9683.t1 Gene3D G3DSA:3.30.200.20 Phosphorylase Kinase; domain 1 1 93 1.2E-36
9 g9683.t1 Gene3D G3DSA:1.10.510.10 Transferase(Phosphotransferase) domain 1 94 184 4.6E-30
2 g9683.t1 PANTHER PTHR24347 SERINE/THREONINE-PROTEIN KINASE 5 184 6.3E-113
3 g9683.t1 PANTHER PTHR24347:SF417 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE (CAM KINASE) II GAMMA 1 5 184 6.3E-113
1 g9683.t1 Pfam PF00069 Protein kinase domain 13 184 2.5E-48
7 g9683.t1 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 19 42 -
6 g9683.t1 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 131 143 -
10 g9683.t1 ProSiteProfiles PS50011 Protein kinase domain profile. 13 184 37.078
5 g9683.t1 SMART SM00220 serkin_6 13 184 8.4E-28
4 g9683.t1 SUPERFAMILY SSF56112 Protein kinase-like (PK-like) 10 184 2.97E-57

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005524 ATP binding MF
GO:0004672 protein kinase activity MF
GO:0006468 protein phosphorylation BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed