General information for g9786.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Arylsulfatase B.
Parent gene
- The parent gene g9786 is located on chr_1: 5202444..5204276 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9786 | g9786.t1 | TTS | g9786.t1 | 5202406 | 5202406 |
| chr_1 | g9786 | g9786.t1 | isoform | g9786.t1 | 5202444 | 5204276 |
| chr_1 | g9786 | g9786.t1 | exon | g9786.t1.exon1 | 5202444 | 5203139 |
| chr_1 | g9786 | g9786.t1 | cds | g9786.t1.CDS1 | 5202444 | 5203139 |
| chr_1 | g9786 | g9786.t1 | exon | g9786.t1.exon2 | 5203196 | 5203353 |
| chr_1 | g9786 | g9786.t1 | cds | g9786.t1.CDS2 | 5203196 | 5203353 |
| chr_1 | g9786 | g9786.t1 | exon | g9786.t1.exon3 | 5203413 | 5203969 |
| chr_1 | g9786 | g9786.t1 | cds | g9786.t1.CDS3 | 5203413 | 5203969 |
| chr_1 | g9786 | g9786.t1 | exon | g9786.t1.exon4 | 5204080 | 5204276 |
| chr_1 | g9786 | g9786.t1 | cds | g9786.t1.CDS4 | 5204080 | 5204276 |
| chr_1 | g9786 | g9786.t1 | TSS | g9786.t1 | 5204305 | 5204305 |
Sequences
>g9786.t1 Gene=g9786 Length=1608
ATGTTCAAGCAATTTAAATTCTTAATATTTCTCACGACACTTAAGTTTGCGTACTTGACC
GATGACCATCAATCGAAAAATGTTATCATAATCGTTGCAGATGATTTAGGATTTCATGAT
TTGAGTTTTAGAGGAAGTAATGAAATTCCTTCGTATAATATTGATGCTTTGGCTTACAAC
GGCATAATTCTTGATCGATTTTATACAGCACCAATGTGTACACCAAGTCGCGCCGCATTA
TTAACAGGCAAATATCCTCATCATTTAGGCATGCAAAATTATGTGATTGTAAGCGATGAA
CCATATGGCCTGCCTCTAGATGTGAAACTTATGCCAGAATTTTTCAAAGATGCTGGTTAT
GTGACACATTTAATTGGAAAATGGCATTTAGGATTTTTTAAAGAAGAATATACACCATTT
CATCGTGGATTCGATCATGTGTTTGGATATCTTGGACCATATATTGATTATTGGGATTAT
ACATTACAAATGTTTAATCGAAATTACTCACGTGGTTATGATTTAAGAAGAAATCTCACA
GTTGATAAAACTTATGATAGAGTTTATGCCACTGATATGTTTACTCAAGAAACAATTAAT
GCAATTGAAAATCATAATCAAGAAAAGCCACTTTTTCTCATACTCAATCATCTCGCTCCA
CATGCTGGAAATGTTGATTTTCCATTGCAAGCCAAAGAAGAAGATTTAAAAAAATTTCCT
TACATTGAAAATGAAGAACGGAAAACATTAGCAGCAATGATAAGTTCATTAGATGAAAGT
GTTGGAAGAATAATTGATGCCTTACATAGAACAGGAATGCTTGAGAATTCAATTATTGTC
TTCTTTTCTGATAACGGTGGACCCACAACTTTTCAACATGCAACAACTGCATCAAATTAT
CCTCTTAGAAGTCAAAAAGAATCAGCATGGGAAGGTGGAATTAGAACAGATGCTTTAATT
TATAGTCCATCTTTACCATCTGGTGTTCTTAGAACTCAATATTTTCATATTTCTGACTTA
CTGCCAACATTGTTGACACTTGCAGAAACGAATATTAAAGTTAAGGATAAAATCGATGGA
ATTGATTTATCGAGAATGATTATGAATGACATGCCACCATATAGAGATGAAATTGTAACA
GTTGATGATGTTTCTGGTTATGGTTCTTATATTTATAGCATTTTTAAACTTGTAAATGGT
TCATCTTCTAATGGTCGAGCAGATGGTTGGATTGGTTCAAATAATAATAGTGATGTTAAT
AAAGATGATTACATTACTGGCGTTCTTAACTCAGACGTAGCACAAATTTTGAAAAATTAT
GAAAATCCACTCATACCTGAAGAGATTTTAGAAATACGTGAAAATGCAACAGTAAAATGC
AGTGGAATAATAAGCGATTGTGATTTGCTTCGAGGTCCATGTTTATTCGACATTTCTCGA
GATCCTTGCGAAGAAAAAAATTTAGAACCAACTAATCCATTACTTTTTGATGCAATGTTA
AAACTTTACCATTCATCTTTAAAAAAGCTTGTACCATCACATAAAAAACCATTAGATCCA
CAATGTGATCCTGCTAATTTCAATTTTACTTGGAAATGGTGGGAGTGA
>g9786.t1 Gene=g9786 Length=535
MFKQFKFLIFLTTLKFAYLTDDHQSKNVIIIVADDLGFHDLSFRGSNEIPSYNIDALAYN
GIILDRFYTAPMCTPSRAALLTGKYPHHLGMQNYVIVSDEPYGLPLDVKLMPEFFKDAGY
VTHLIGKWHLGFFKEEYTPFHRGFDHVFGYLGPYIDYWDYTLQMFNRNYSRGYDLRRNLT
VDKTYDRVYATDMFTQETINAIENHNQEKPLFLILNHLAPHAGNVDFPLQAKEEDLKKFP
YIENEERKTLAAMISSLDESVGRIIDALHRTGMLENSIIVFFSDNGGPTTFQHATTASNY
PLRSQKESAWEGGIRTDALIYSPSLPSGVLRTQYFHISDLLPTLLTLAETNIKVKDKIDG
IDLSRMIMNDMPPYRDEIVTVDDVSGYGSYIYSIFKLVNGSSSNGRADGWIGSNNNSDVN
KDDYITGVLNSDVAQILKNYENPLIPEEILEIRENATVKCSGIISDCDLLRGPCLFDISR
DPCEEKNLEPTNPLLFDAMLKLYHSSLKKLVPSHKKPLDPQCDPANFNFTWKWWE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g9786.t1 | CDD | cd16029 | 4-S | 27 | 400 | 2.34937E-172 |
| 2 | g9786.t1 | PANTHER | PTHR10342 | ARYLSULFATASE | 13 | 535 | 1.6E-200 |
| 3 | g9786.t1 | PANTHER | PTHR10342:SF264 | MIP05773P | 13 | 535 | 1.6E-200 |
| 1 | g9786.t1 | Pfam | PF00884 | Sulfatase | 26 | 348 | 2.6E-66 |
| 9 | g9786.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 19 | - |
| 10 | g9786.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 6 | - |
| 11 | g9786.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 7 | 14 | - |
| 12 | g9786.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 15 | 19 | - |
| 8 | g9786.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 20 | 535 | - |
| 5 | g9786.t1 | ProSitePatterns | PS00523 | Sulfatases signature 1. | 71 | 83 | - |
| 6 | g9786.t1 | ProSitePatterns | PS00149 | Sulfatases signature 2. | 119 | 129 | - |
| 4 | g9786.t1 | SUPERFAMILY | SSF53649 | Alkaline phosphatase-like | 25 | 534 | 1.28E-110 |
| 7 | g9786.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 19 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008484 | sulfuric ester hydrolase activity | MF |
| GO:0003824 | catalytic activity | MF |
KEGG
Orthology
- This transcript has been annotated with K01135 (arylsulfatase B)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed