Gene loci information

Transcript annotation

  • This transcript has been annotated as GPI mannosyltransferase 2.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g9790 g9790.t1 TTS g9790.t1 5213995 5213995
chr_1 g9790 g9790.t1 isoform g9790.t1 5214080 5215498
chr_1 g9790 g9790.t1 exon g9790.t1.exon1 5214080 5215498
chr_1 g9790 g9790.t1 cds g9790.t1.CDS1 5214080 5215498
chr_1 g9790 g9790.t1 TSS g9790.t1 5215781 5215781

Sequences

>g9790.t1 Gene=g9790 Length=1419
ATGCCAACAAATATTACAAAACTAGCAATCTTTAGTCGTTTATTTGTGATTTTTCTGCAA
TGCGTATCTAATCATTTAATTGAAGACCACAATGCAGACGATGTTTTTAGAGCGCCTATT
GATACCGCAGTGCGAAAGAAAAAATGTGATACAATTGTTGAATTCTTGCTTGGTGGATTT
CGTCGATGGGATGCACAATATTTCTTACATATATCAGAGCATGGATATACATATGAAAAT
ACTTTAGCGTTTTATCCTTTATATCCACTGTCTATCAAAATGATACGCTATGTTTTCATC
AATATTACACCATTTCTCACAGTTCGATCATTGTCTTTGCTCATTGGAGTCGTCCTTAAT
GTGATATTTTTCGTCAAAGCAACAAACTCACTTTATGAGTTAGCAAAGAAAGTCTTGAAA
GATCAAAGAAAAGCTGAAGTGGCTGCCATTCTTTTTTGCTTCAATCCTGCCTCAATTTTC
TTCACTGCACCATATTCAGAAAGTCTTTATAGTTGGCTGAGTTTTTCATTAATGCTAAAA
TGTTTTGACGATATCAATTCCGTGCTGATAGTTGTTCCATTAAGCTGCAGCATTCTAACA
CGATCAAATGGTTTAATTAATATAGGATTTGTAGTATATTATGGACTTAAGAAAATGTTT
AATCAAAACACTGTTCTATCATTTGTGACAGTGTTTTTAAAAATCTTTTCCATACTCATC
ATTATCGCATTTCATTTTGGATTAATGCAGGTCTACAATTATTATCTCTTTTGCTTCCAA
AAGTCATTCAATTTTCCTGATTTTATAAAAGATTTTGCATTAGAAAACGACCTTGTGCTT
GCAGGCAATCGATCAAGCACTTCAAATGAATCCGTGTCACCATGGTGCTTAAGTAATTTT
CCAGTTGCATATTCGTACATTCAAGAGCATTATTGGAATGTTGGCTATATGAATTACTAT
GAATTCAAACAAATTCCAAATTTTCTATTAGCTGCTCCAATAGTTTTAATAATCCTAGTC
AATGCATTTATTTATTTCATCAACAATCAAGATTATTGTTGGAGATTAGGAATTTTTAAT
TTGAGGCAATCAATTTTAAGAAAAACCTCAATAGCAGATCAAAATCAATTTGTATTTATC
GTTCATGCTGTGGCCATGTGTTTATTTTGTATTTTCTTCATACATGTTCAAGTGACTACT
CGGATCTTGGCATCTTCAAATCCAATGCTCTATTTCTTTTGTGCAAATTATTTCATGCCA
GAATCAGGTGCTCATAAGAAAAATGATGATAAAATTAATGAAGTACATGTTTTTGATATA
AAGAAATTAAATTGGACACAACGATTTATTGTTTATTATTTCATTGGCTACTATTCTCTT
GGAACTGTTTTATTTAGTAACTTCTTTCCATGGACTTAA

>g9790.t1 Gene=g9790 Length=472
MPTNITKLAIFSRLFVIFLQCVSNHLIEDHNADDVFRAPIDTAVRKKKCDTIVEFLLGGF
RRWDAQYFLHISEHGYTYENTLAFYPLYPLSIKMIRYVFINITPFLTVRSLSLLIGVVLN
VIFFVKATNSLYELAKKVLKDQRKAEVAAILFCFNPASIFFTAPYSESLYSWLSFSLMLK
CFDDINSVLIVVPLSCSILTRSNGLINIGFVVYYGLKKMFNQNTVLSFVTVFLKIFSILI
IIAFHFGLMQVYNYYLFCFQKSFNFPDFIKDFALENDLVLAGNRSSTSNESVSPWCLSNF
PVAYSYIQEHYWNVGYMNYYEFKQIPNFLLAAPIVLIILVNAFIYFINNQDYCWRLGIFN
LRQSILRKTSIADQNQFVFIVHAVAMCLFCIFFIHVQVTTRILASSNPMLYFFCANYFMP
ESGAHKKNDDKINEVHVFDIKKLNWTQRFIVYYFIGYYSLGTVLFSNFFPWT

Protein features from InterProScan

Transcript Database ID Name Start End E.value
2 g9790.t1 PANTHER PTHR12468 GPI MANNOSYLTRANSFERASE 2 4 472 1.8E-116
1 g9790.t1 Pfam PF04188 Mannosyltransferase (PIG-V) 4 472 5.4E-90
20 g9790.t1 Phobius SIGNAL_PEPTIDE Signal peptide region 1 23 -
21 g9790.t1 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide. 1 7 -
22 g9790.t1 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide. 8 19 -
31 g9790.t1 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide. 20 23 -
18 g9790.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 24 96 -
24 g9790.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 97 125 -
12 g9790.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 126 144 -
28 g9790.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 145 165 -
17 g9790.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 166 184 -
25 g9790.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 185 213 -
11 g9790.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 214 224 -
29 g9790.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 225 246 -
19 g9790.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 247 327 -
30 g9790.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 328 347 -
14 g9790.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 348 376 -
23 g9790.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 377 396 -
16 g9790.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 397 401 -
27 g9790.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 402 419 -
13 g9790.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 420 449 -
26 g9790.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 450 469 -
15 g9790.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 470 472 -
10 g9790.t1 SignalP_EUK SignalP-noTM SignalP-noTM 1 24 -
6 g9790.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 105 127 -
9 g9790.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 148 170 -
5 g9790.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 190 212 -
4 g9790.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 225 247 -
3 g9790.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 325 347 -
7 g9790.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 377 399 -
8 g9790.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 449 471 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006506 GPI anchor biosynthetic process BP
GO:0000009 alpha-1,6-mannosyltransferase activity MF
GO:0004376 glycolipid mannosyltransferase activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values