Gene loci information

Transcript annotation

  • This transcript has been annotated as Angiotensin-converting enzyme .

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g986 g986.t2 isoform g986.t2 7261108 7262357
chr_3 g986 g986.t2 exon g986.t2.exon1 7261108 7261200
chr_3 g986 g986.t2 cds g986.t2.CDS1 7261110 7261200
chr_3 g986 g986.t2 exon g986.t2.exon2 7261257 7261414
chr_3 g986 g986.t2 cds g986.t2.CDS2 7261257 7261414
chr_3 g986 g986.t2 exon g986.t2.exon3 7261468 7262357
chr_3 g986 g986.t2 cds g986.t2.CDS3 7261468 7262262
chr_3 g986 g986.t2 TSS g986.t2 NA NA
chr_3 g986 g986.t2 TTS g986.t2 NA NA

Sequences

>g986.t2 Gene=g986 Length=1141
CTCTTTCGGTTTCAACACCAAAACATTTGGAGAAAGTTGGTCTTTTAAGTGGTTACCAAA
ACAGTGAGGCTGACAATATCAACGCACTTTTCCATATGGCACTCGAACGTGTTGCTTTCC
TTCCATTTGGTTTGTTGATTGATAAATGGCGTTGGGACTTATTTAGTGGTGCAACACCTG
AATCTGAATGGAATAAACATTGGTGGGAACTACGAGAAAAATACCAAAAAATTCGAGCAC
CATCACCTCGTGGTGAAGAATTTTTCGATCCAGGCGCAAAATATCACATTCCAGCTGATT
CACAATACATTGCATATTTTGTTGCTCATATTTTGGAATTTAGTTTCTATAAAAGCCTTT
GTATTGAAGCAGGTCAATATAATGTTTCAAATCCATCAGAACATCCACTTCATACATGTG
ATTTCTTCGAAAGTAAAGCAGCTGGTGAAAAACTAAATGCTGGTTTAAAACTTGGCATGA
GCAAACATTGGAGTGAAGCACTTAATGAACTTACAGGATCACCAAATATTTCAGCATCAG
CACTTGTTGAATATTTTGCACCACTCAAAGATTATTTGGCTGAACAAAATAAAATTATGA
AAAATGCAAGAATGGCAGAAATTCTTCAAGAATATGAAGTAGAAGGATCTGCAATGTGCA
ATAAATTGGTTAAAGCTGAATGGGCAGTTGCTACTGATTCCAATAATGATGCTTTAAAGA
CAGAATATGAAAGAATTGTACTAGAAAACAATGCCTTTACCAAAGATTATTATGAAAAAG
CATTTAAAGGAGAAAAACCAGAAGATTATAATGATGAATTAATTCAAAGACAATTAAAAT
ATTTGACAAAACTTGGTCGTGATGCTTTGGAAATTGCAGATTTAAGCAATTTGACAAACA
CACAAACTCGCATGGAAAAAATTTATAATACAGCAAAAATTTGTCCATTTAATAAACAAA
ATTGTAATTTAGCTACAGAAGGTCTTACACTTGATCCTGATCTTTCTGATCTGTTAGCTA
CTTCTACAAACTATGATGAATTAGAATGGGCTTGGACACAATGGCGTGAAAAGAGTGGAA
AACTTATGAGAGATGACTACAAAATTTATATTGAACTTCTTAATGAAGCTGCTAAATTAA
A

>g986.t2 Gene=g986 Length=348
MALERVAFLPFGLLIDKWRWDLFSGATPESEWNKHWWELREKYQKIRAPSPRGEEFFDPG
AKYHIPADSQYIAYFVAHILEFSFYKSLCIEAGQYNVSNPSEHPLHTCDFFESKAAGEKL
NAGLKLGMSKHWSEALNELTGSPNISASALVEYFAPLKDYLAEQNKIMKNARMAEILQEY
EVEGSAMCNKLVKAEWAVATDSNNDALKTEYERIVLENNAFTKDYYEKAFKGEKPEDYND
ELIQRQLKYLTKLGRDALEIADLSNLTNTQTRMEKIYNTAKICPFNKQNCNLATEGLTLD
PDLSDLLATSTNYDELEWAWTQWREKSGKLMRDDYKIYIELLNEAAKL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
4 g986.t2 PANTHER PTHR10514 ANGIOTENSIN-CONVERTING ENZYME 1 167 0
3 g986.t2 PANTHER PTHR10514 ANGIOTENSIN-CONVERTING ENZYME 167 347 0
5 g986.t2 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 33 60 0
6 g986.t2 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 61 89 0
2 g986.t2 Pfam PF01401 Angiotensin-converting enzyme 1 167 0
1 g986.t2 Pfam PF01401 Angiotensin-converting enzyme 170 347 0
8 g986.t2 SUPERFAMILY SSF55486 Metalloproteases (zincins), catalytic domain 1 166 0
7 g986.t2 SUPERFAMILY SSF55486 Metalloproteases (zincins), catalytic domain 171 348 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016020 membrane CC
GO:0008241 peptidyl-dipeptidase activity MF
GO:0008237 metallopeptidase activity MF
GO:0006508 proteolysis BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed