Gene loci information

Transcript annotation

  • This transcript has been annotated as Voltage-dependent calcium channel subunit alpha-2/delta-3.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g9939 g9939.t3 isoform g9939.t3 6114776 6116025
chr_1 g9939 g9939.t3 exon g9939.t3.exon1 6114776 6116025
chr_1 g9939 g9939.t3 cds g9939.t3.CDS1 6114776 6115915
chr_1 g9939 g9939.t3 TSS g9939.t3 6116430 6116430
chr_1 g9939 g9939.t3 TTS g9939.t3 NA NA

Sequences

>g9939.t3 Gene=g9939 Length=1250
GTGAATTTATAACTAGAAAAAATGATGTGGTGCAAAGTTTTAAGCAGGCACAAATTGTGA
ATCGATCTGGTTCAGTTATAGTGGAAGAGATAGCAAAAGAGATTAAAAAGATGATGGATG
CTCGAATAAGTGCCATCAAACGTATAGTTGACACAGCTCAAGAAGTAGGATCAATATCAG
CGAGTAATGACGAAGTGGTAGAAAAAAATTTTACATATTACAACTCAAAGCAAATGATAG
AACCGAGTGAAGTGTCACTAAATGAGTCCCCAATAACATCTGATGGTGAAGAAAATTTAG
ATAAATTAGAATTGCCCAAACCTGTGATTTATTTAACCGAAAGCGAAAAGTTTAGCGATT
ATGTGAATTTATCATTAAGTTCAGTTCACGTCCCTACAAATGTATATGATAGAGCAAAAA
ATGTCATTAAAGCCATCAAGTGGTCTGAAGTGCTTGATAATATTTTCGATAGCAATTACA
AACGTGATCCATCACTTTTTTGGCAATTTTTTTGTAGTTCAACAGGTTTCATGCGTCAAT
TTCCAGCAACTAAATGGAAATTTGATCCCGTTGATCTTTACGATTGCCGAATCAGACATT
GGTATATTGCTGCAGCAAACAGTCCAAAAGATATGATAATTTTGATTGACAATTCTGGTT
CAATGACCGGTCAGAAAAAGGATATTGCGAGACATATTGTTGAAAACATTCTCGACACAC
TTACACCCAATGATTTTGTCAACATTTTTACATTTTCTGACTTGATTCGTGATGTTGTCG
ACTGTTTTGGTGATACACTTGTTCAAGCTAATTCTGCCAATATTCGAGCGATGAAAGAAT
CTTTGCACAATATTGAAACTAATGAGCTTGCAAATTTTTCTGCAGCACTAACGAGAGCTT
TTGATACACTCTCTAATTATCGTCATACTGGTGCAAATTGTAATCAGGCCATTATGTTGA
TTTCTGATGGACTTCCAATATCAGTCGATGATGTATTTGAAATTTATAATTGGGGCGAGA
AGCCAAATATTCCTGTTCGTGTCTTTACATATTTGATTGGTCGTGAAGTCCCAGATGTGA
AAAATATAAAAGATATGGCATGCAATAATCGGGGATTTTATGTGCATATAAATACATTGG
CTGAAGTTCGTGAACAAGTTTTAGAATATATTCCTGTCATGGCTCGACCTCTTGTACTTA
ATCGAACTCATCATCCTATAGTATGGTCACATATCTATGCAGACGTTGTG

>g9939.t3 Gene=g9939 Length=380
MMDARISAIKRIVDTAQEVGSISASNDEVVEKNFTYYNSKQMIEPSEVSLNESPITSDGE
ENLDKLELPKPVIYLTESEKFSDYVNLSLSSVHVPTNVYDRAKNVIKAIKWSEVLDNIFD
SNYKRDPSLFWQFFCSSTGFMRQFPATKWKFDPVDLYDCRIRHWYIAAANSPKDMIILID
NSGSMTGQKKDIARHIVENILDTLTPNDFVNIFTFSDLIRDVVDCFGDTLVQANSANIRA
MKESLHNIETNELANFSAALTRAFDTLSNYRHTGANCNQAIMLISDGLPISVDDVFEIYN
WGEKPNIPVRVFTYLIGREVPDVKNIKDMACNNRGFYVHINTLAEVREQVLEYIPVMARP
LVLNRTHHPIVWSHIYADVV

Protein features from InterProScan

Transcript Database ID Name Start End E.value
7 g9939.t3 Gene3D G3DSA:3.40.50.410 - 173 354 0.000
3 g9939.t3 PANTHER PTHR10166:SF31 RE14947P 1 379 0.000
4 g9939.t3 PANTHER PTHR10166 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED 1 379 0.000
1 g9939.t3 Pfam PF08399 VWA N-terminal 24 149 0.000
2 g9939.t3 Pfam PF13519 von Willebrand factor type A domain 175 287 0.000
8 g9939.t3 ProSiteProfiles PS50234 VWFA domain profile. 174 361 15.976
6 g9939.t3 SMART SM00327 VWA_4 172 351 0.000
5 g9939.t3 SUPERFAMILY SSF53300 vWA-like 172 353 0.000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

There are no GO annotations for this transcript.

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values