KEGG pathway : ko04218

ko04218: Cellular senescence

Genes annotated with KAAS are mapped onto the ko04218 map with pathview. genes colored in red are conserved in P. vanderplanki.

Orthologs for this pathway

• K00922
  • EC:2.7.1.153: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  • g12521
• K01110
  • EC:3.1.3.16: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
  • g5232
• K01110
  • EC:3.1.3.48: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
  • g5232
• K01110
  • EC:3.1.3.67: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
  • g5232
• K02087
  • EC:2.7.11.22: cyclin-dependent kinase 1
  • g13105
• K02087
  • EC:2.7.11.23: cyclin-dependent kinase 1
  • g13105
• K02089
  • EC:2.7.11.22: cyclin-dependent kinase 4
  • g8600
• K02091
  • EC:2.7.11.22: cyclin-dependent kinase 6
  • g8600
• K02183
  • Other:Other
  • g10355, g11432
• K02206
  • EC:2.7.11.22: cyclin-dependent kinase 2
  • g2875
• K02216
  • EC:2.7.11.1: serine/threonine-protein kinase CHEK1
  • g5091
• K02580
  • Other:Other
  • g8884
• K02649
  • Other:Other
  • g8805
• K02678
  • Other:Other
  • g2900
• K03362
  • Other:Other
  • g11473
• K04348
  • EC:3.1.3.16: serine/threonine-protein phosphatase 2B catalytic subunit
  • g1333
• K04368
  • EC:2.7.12.2: mitogen-activated protein kinase kinase 1
  • g2128
• K04371
  • EC:2.7.11.24: mitogen-activated protein kinase 1/3
  • g9093
• K04377
  • Other:Other
  • g14105
• K04402
  • Other:Other
  • g7938
• K04432
  • EC:2.7.12.2: mitogen-activated protein kinase kinase 3
  • g12056
• K04441
  • EC:2.7.11.24: p38 MAP kinase
  • g10681
• K04443
  • EC:2.7.11.1: mitogen-activated protein kinase-activated protein kinase 2
  • g11439
• K04456
  • EC:2.7.11.1: RAC serine/threonine-protein kinase
  • g11018, g11019
• K04674
  • EC:2.7.11.30: TGF-beta receptor type-1
  • g9855
• K04681
  • Other:Other
  • g8044
• K04728
  • EC:2.7.11.1: serine-protein kinase ATM
  • g13725
• K04851
  • Other:Other
  • g16833
• K04958
  • Other:Other
  • g14909, g14904
• K05863
  • Other:Other
  • g6957
• K05864
  • EC:5.2.1.8: peptidyl-prolyl isomerase D
  • g9331
• K06268
  • Other:Other
  • g16318, g8138
• K06269
  • EC:3.1.3.16: serine/threonine-protein phosphatase PP1 catalytic subunit
  • g2191
• K06620
  • Other:Other
  • g10855, g1101
• K06626
  • Other:Other
  • g5510
• K06627
  • Other:Other
  • g7137
• K06640
  • EC:2.7.11.1: serine/threonine-protein kinase ATR
  • g9649
• K06641
  • EC:2.7.11.1: serine/threonine-protein kinase CHEK2
  • g2287
• K06643
  • EC:2.3.2.27: E3 ubiquitin-protein ligase Mdm2
  • g12122
• K07203
  • EC:2.7.11.1: serine/threonine-protein kinase mTOR
  • g13452
• K07206
  • Other:Other
  • g2022
• K07207
  • Other:Other
  • g9369
• K07208
  • Other:Other
  • g9421
• K07827
  • Other:Other
  • g3228
• K07830
  • Other:Other
  • g11648
• K08826
  • EC:2.7.11.1: homeodomain interacting protein kinase
  • g8824
• K09183
  • Other:Other
  • g10390, g10393
• K09408
  • Other:Other
  • g363
• K10151
  • Other:Other
  • g12224
• K10752
  • Other:Other
  • g10505
• K10865
  • Other:Other
  • g8187, g17418
• K10866
  • Other:Other
  • g16383, g5624
• K11411
  • EC:2.3.1.286: NAD+-dependent protein deacetylase sirtuin 1
  • g3772
• K15040
  • Other:Other
  • g4858
• K18753
  • Other:Other
  • g3962
• K20858
  • Other:Other
  • g7302
• K21769
  • Other:Other
  • g12063
• K21770
  • Other:Other
  • g3839
• K21771
  • Other:Other
  • g7973
• K21773
  • Other:Other
  • g10830
• K21774
  • Other:Other
  • g8223
• K21775
  • Other:Other
  • g3561
• K21776
  • Other:Other
  • g1947
• K23605
  • Other:Other
  • g11287