KEGG pathway : ko05230

ko05230: Central carbon metabolism in cancer

Genes annotated with KAAS are mapped onto the ko05230 map with pathview. genes colored in red are conserved in P. vanderplanki.

Orthologs for this pathway

• K00016
  • EC:1.1.1.27: L-lactate dehydrogenase
  • g7339, g6243
• K00031
  • EC:1.1.1.42: isocitrate dehydrogenase
  • g10682, g429
• K00036
  • EC:1.1.1.49: glucose-6-phosphate 1-dehydrogenase
  • g2640
• K00036
  • EC:1.1.1.363: glucose-6-phosphate 1-dehydrogenase
  • g2640
• K00161
  • EC:1.2.4.1: pyruvate dehydrogenase E1 component alpha subunit
  • g950, g9425
• K00162
  • EC:1.2.4.1: pyruvate dehydrogenase E1 component beta subunit
  • g7167
• K00844
  • EC:2.7.1.1: hexokinase
  • g1897, g2925
• K00850
  • EC:2.7.1.11: 6-phosphofructokinase 1
  • g10749
• K00873
  • EC:2.7.1.40: pyruvate kinase
  • g160
• K00922
  • EC:2.7.1.153: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  • g12521
• K01110
  • EC:3.1.3.16: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
  • g5232
• K01110
  • EC:3.1.3.48: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
  • g5232
• K01110
  • EC:3.1.3.67: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
  • g5232
• K01425
  • EC:3.5.1.2: glutaminase
  • g7607, g7606
• K01834
  • EC:5.4.2.11: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
  • g2619
• K02649
  • Other:Other
  • g8805
• K04361
  • EC:2.7.10.1: epidermal growth factor receptor
  • g5568
• K04362
  • EC:2.7.10.1: fibroblast growth factor receptor 1
  • g16687
• K04368
  • EC:2.7.12.2: mitogen-activated protein kinase kinase 1
  • g2128
• K04371
  • EC:2.7.11.24: mitogen-activated protein kinase 1/3
  • g9093
• K04377
  • Other:Other
  • g14105
• K04456
  • EC:2.7.11.1: RAC serine/threonine-protein kinase
  • g11018, g11019
• K05093
  • EC:2.7.10.1: fibroblast growth factor receptor 2
  • g2994
• K05126
  • EC:2.7.10.1: proto-oncogene tyrosine-protein kinase Ret
  • g4472
• K07203
  • EC:2.7.11.1: serine/threonine-protein kinase mTOR
  • g13452
• K07299
  • Other:Other
  • g8819
• K07827
  • Other:Other
  • g3228
• K08268
  • Other:Other
  • g1184
• K11416
  • EC:2.3.1.286: NAD+-dependent protein deacetylase sirtuin 6
  • g15776
• K13780
  • Other:Other
  • g7682, g3175, g3622