General information for g11447.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Tyrosine-protein kinase Src64B.
Parent gene
- The parent gene g11447 is located on chr_1: 16312665..16313887 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11447 | g11447.t3 | TSS | g11447.t3 | 16311099 | 16311099 |
| chr_1 | g11447 | g11447.t3 | isoform | g11447.t3 | 16311602 | 16312417 |
| chr_1 | g11447 | g11447.t3 | exon | g11447.t3.exon1 | 16311602 | 16311821 |
| chr_1 | g11447 | g11447.t3 | cds | g11447.t3.CDS1 | 16311602 | 16311821 |
| chr_1 | g11447 | g11447.t3 | exon | g11447.t3.exon2 | 16311959 | 16312095 |
| chr_1 | g11447 | g11447.t3 | cds | g11447.t3.CDS2 | 16311959 | 16312095 |
| chr_1 | g11447 | g11447.t3 | exon | g11447.t3.exon3 | 16312151 | 16312224 |
| chr_1 | g11447 | g11447.t3 | cds | g11447.t3.CDS3 | 16312151 | 16312224 |
| chr_1 | g11447 | g11447.t3 | exon | g11447.t3.exon4 | 16312298 | 16312417 |
| chr_1 | g11447 | g11447.t3 | cds | g11447.t3.CDS4 | 16312298 | 16312415 |
| chr_1 | g11447 | g11447.t3 | TTS | g11447.t3 | NA | NA |
Sequences
>g11447.t3 Gene=g11447 Length=551
ATGGGCAATAAATGCTGCTCTAAAAGACAACCCGACGATTTTGCAACTGCAACAGGAGGA
TATAAGAAAAATGAAACAATTTTTATTCAGTCAAATCCTAAAAATAACAGTAATTCGCTC
GAATCCCGTTACACACCAGATCCGAATCGTGGTGGAAGTGGTACAAAACATGCAAAAAGT
GGAATAGATATCATAAGAAGCGGTGGAGCAAGGAGCATAACGCATCCAGTAAGTCATCGC
AGAATCGTTGTTGCTTTATACAACTATAATGCGAGAGAAGATACAGATGTATCGTTTGTC
AAGGGTGATCGTATGGAAGTACTCGATGACACTGAATCCGATTGGTGGCGAGTTATCCAT
TTAACCACTCGACAAGAGGGTCTAATTCCATGGAATTTTGTTGCGGAAGAGAGAAGTGTT
AATAGCGAAGATTGGTTCTTTGAAAATATTTCTCGAAAAGAAGCTGATAAACTCTTGTTG
GCTGAAGAGAATCCACGGGGAACATTTTTAATTCGTCCATCTGAACACAATCCTAATGGA
TTTTCACTAAG
>g11447.t3 Gene=g11447 Length=183
MGNKCCSKRQPDDFATATGGYKKNETIFIQSNPKNNSNSLESRYTPDPNRGGSGTKHAKS
GIDIIRSGGARSITHPVSHRRIVVALYNYNAREDTDVSFVKGDRMEVLDDTESDWWRVIH
LTTRQEGLIPWNFVAEERSVNSEDWFFENISRKEADKLLLAEENPRGTFLIRPSEHNPNG
FSL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g11447.t3 | CDD | cd11845 | SH3_Src_like | 82 | 133 | 0.000 |
| 10 | g11447.t3 | Gene3D | G3DSA:2.30.30.40 | SH3 Domains | 77 | 135 | 0.000 |
| 11 | g11447.t3 | Gene3D | G3DSA:3.30.505.10 | SHC Adaptor Protein | 136 | 183 | 0.000 |
| 3 | g11447.t3 | PANTHER | PTHR24418:SF224 | TYROSINE-PROTEIN KINASE FGR | 1 | 183 | 0.000 |
| 4 | g11447.t3 | PANTHER | PTHR24418 | TYROSINE-PROTEIN KINASE | 1 | 183 | 0.000 |
| 8 | g11447.t3 | PRINTS | PR00452 | SH3 domain signature | 81 | 91 | 0.000 |
| 5 | g11447.t3 | PRINTS | PR00452 | SH3 domain signature | 95 | 110 | 0.000 |
| 6 | g11447.t3 | PRINTS | PR00452 | SH3 domain signature | 112 | 121 | 0.000 |
| 7 | g11447.t3 | PRINTS | PR00452 | SH3 domain signature | 125 | 137 | 0.000 |
| 1 | g11447.t3 | Pfam | PF00018 | SH3 domain | 84 | 130 | 0.000 |
| 2 | g11447.t3 | Pfam | PF00017 | SH2 domain | 145 | 183 | 0.000 |
| 14 | g11447.t3 | ProSiteProfiles | PS50002 | Src homology 3 (SH3) domain profile. | 78 | 139 | 23.791 |
| 15 | g11447.t3 | ProSiteProfiles | PS50001 | Src homology 2 (SH2) domain profile. | 145 | 183 | 13.548 |
| 13 | g11447.t3 | SMART | SM00326 | SH3_2 | 81 | 138 | 0.000 |
| 9 | g11447.t3 | SUPERFAMILY | SSF50044 | SH3-domain | 77 | 182 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
