Gene loci information

Transcript annotation

  • This transcript has been annotated as Disheveled-associated activator of morphogenesis 1-A.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g11568 g11568.t1 isoform g11568.t1 17181418 17187982
chr_1 g11568 g11568.t1 exon g11568.t1.exon1 17181418 17181474
chr_1 g11568 g11568.t1 cds g11568.t1.CDS1 17181418 17181474
chr_1 g11568 g11568.t1 exon g11568.t1.exon2 17183442 17183660
chr_1 g11568 g11568.t1 cds g11568.t1.CDS2 17183442 17183660
chr_1 g11568 g11568.t1 exon g11568.t1.exon3 17184031 17184600
chr_1 g11568 g11568.t1 cds g11568.t1.CDS3 17184031 17184600
chr_1 g11568 g11568.t1 exon g11568.t1.exon4 17184674 17185904
chr_1 g11568 g11568.t1 cds g11568.t1.CDS4 17184674 17185904
chr_1 g11568 g11568.t1 exon g11568.t1.exon5 17185969 17186225
chr_1 g11568 g11568.t1 cds g11568.t1.CDS5 17185969 17186225
chr_1 g11568 g11568.t1 exon g11568.t1.exon6 17186323 17186462
chr_1 g11568 g11568.t1 cds g11568.t1.CDS6 17186323 17186462
chr_1 g11568 g11568.t1 exon g11568.t1.exon7 17186533 17186694
chr_1 g11568 g11568.t1 cds g11568.t1.CDS7 17186533 17186694
chr_1 g11568 g11568.t1 exon g11568.t1.exon8 17186776 17187339
chr_1 g11568 g11568.t1 cds g11568.t1.CDS8 17186776 17187339
chr_1 g11568 g11568.t1 exon g11568.t1.exon9 17187398 17187569
chr_1 g11568 g11568.t1 cds g11568.t1.CDS9 17187398 17187569
chr_1 g11568 g11568.t1 exon g11568.t1.exon10 17187637 17187784
chr_1 g11568 g11568.t1 cds g11568.t1.CDS10 17187637 17187784
chr_1 g11568 g11568.t1 exon g11568.t1.exon11 17187867 17187982
chr_1 g11568 g11568.t1 cds g11568.t1.CDS11 17187867 17187982
chr_1 g11568 g11568.t1 TTS g11568.t1 17188074 17188074
chr_1 g11568 g11568.t1 TSS g11568.t1 NA NA

Sequences

>g11568.t1 Gene=g11568 Length=3636
ATGTGCAGTATTAATACGAAACATCATTTTAATATCCTAATGGATAAATTGAATCTTTCT
ATTCCATCTTGCTCAATACCAATACCGTCAGCATTTCAAAATCTTCCACGACTTTGTCCG
TCTTGGTGCCACGAATCGGAAGATTCAGGAAACAACGCAGCAGCAACCACTGCACAAGCA
TTTTCCCAATCAGCAGTCAATCTAATCCACGCTCCACCTAAATATCACCAGAAGAAAATG
CCTTTTCGCAAGAAAAATTGGTGTGGCTGCATTCAGGATGACGAACCACCTGAGATTTGT
GTGGTTGAAGGTGTTTTTTCATTGGAAAATCTTACACCAACACAACCGATGCCAAGTGCT
GAAGAACTTGAAGAGAAATTTAGCGAACTTGTTGAAGAACTTGATTTAACGGAAGCAAAT
AAAGCACAAATGATGAATCTGCCTAGCGCCAAGAAATGGCAAATTTATTGCAGTCGAAAA
ATTCCAACAGAGTCAATCGAGTCACCAGATGGCTGTGCATCGTCAACAATTTCGAACTTT
GAAAAAACACCATTGTTTTATGTTGAAAGACTTCGTGAAATTACTTCACAACTACGAATA
ACAACTGACGATTCGCCAAAACACAATGACTTTCAACTAAAAATTGAACAACAAACAGCA
CTTTGTGATGCACTCAAAACTGCATTAAGAACAGCAGCACATAGCTTTGTTTTGAAATTT
ATTGAGTCTCAAGGACTTGCAGCTTTATTGGACACTTTAGAAGCTGTGACAACTGTTTTT
ATAATTGCAAATAGTTCATTACATACAAGCATTATAGGATGCATTAAAGCATTGATGAAT
AACTCGACCGGTCGTTCACACGTGCTGCAACATCCAACATCAATCAATATTATCGCAAAA
TCACTGGCTTGTGAAAATACTAAAACAAAAGTTGCTGTCTTAGAAATACTTGGTGCGGTA
TGTCTTGTGCAAGGTGGTCACAAAAAAGTACTCGAAGCATTTATAAGCTTTCAAGAATTT
GCATCAGAACGTACTCGATTTCAGAGTATAATGAATGATCTTGATCGTTCAATAGGCTCT
TATAGAGATGAAACAAATTTAAAAGTAGCAATTATGTCACTAATTAATGCTTTAGTAAAT
TATGGAGCAGGCGAAGATCAACTTGAATTTCGTTTACATTTACGATTTGAATTTATTATG
TTAGGCATAGAAAAAACCATCCAAAAATTACGAAAATATGAGAATGAAACGCTTGATCGG
CATTTAGACTTTTTCGAAATGGTCAGATTGGAAGATGAAAAAGAATTGTCAAGAAAGTTT
AGTAATGAATCCATTGAGGCAGAAAGTGCCATTGAAATATTTGATCTATTGCGACGAAAG
CTAAATTATTCGGCAGCCTATCCTCATTTTTTGTCAATGTTGCAACACATGATGTTGCTG
CCATTTACAAGCTCTAATACACACTACTGGTTGCTATTTGATCGAATTCTGCAACAAATT
GTGCTACAGCAAAGTGATCAGAGGCCGTCAAGTGAAATTGAGAGTTTCTTTGAAGAGCAC
ATGCCATCGGAAAATTCAAAGCCAAAATTCACAAACCCTGATGTTACTCCAATTGAAATT
GATGTCAATAAAATTGTTAAGCTGTTGGTGCGTGAAGAGGAACTAATTAATGCCCGAAGG
AAAGCTGAAGAACTTGAAAGGGAAAATTTAGAATTTGTTGCAAAACTTTCGAAAAAAGAG
CGTGAACTTGATTTACGAACAGCTGAAAAAGAAGATCTTGAAACAAATTTAATAAGAATG
CGAGAGCGACTCGAAAAAGAGAGTACAAATCATTCGCAAGCTGTGACAAGAGCGATTAAT
GCTGAAATGAAAATAGAAGATTTACAGCATAAACTAGTCAATGAACAGCAAGAAAGACTT
CGTCTTGAAAAGCTCATGTCAGAAGGTTCATTTCCAGATGATCAAAAAGCTGCTGGTTTG
CAAGTTAATAAAGAAAATTGCAATATTGAGTCATTAAATTCTTCTGTACCTCCTCCTCCG
CCAATTCCACAATGTGCACCTGCACCACCACCACCTGCATGTCCACCACCGCCACCATCA
TTGAAAGGTCTTCCAATGGCACCACCACTTCCAAAGGTCGAAGTATCAAAGAAAAATATT
CCATCATCGAGTCAACCACTTAAAAGTTTCAATTGGTCAAAGCTTCCTGAATTAAAAATC
CAAAATACTGTATGGAGCGAACTAGACGAAACAAAATGGTATAATAGCATGGATCTTGAG
TCAATCGACAAACTCTTCTCAGCATATCAAAATCAAAAGAATGAACGTAATGGTGTTGAT
GGATCAAGCATAGAAGACTTGCGGTTAATTGGTAAAGGCAAAACAAAAATACTCTCTGTT
ATCGATGGTAGACGAGCACAAAATTGCACAATTTTACTCAGTAAATTGAAAATGACTGAT
GATGAAATTTCAAAAGCGATACTGTCGATGGATAGTAATGATCAGTTACCGATCGATATG
GTTGAACAACTACTCAAGTTCACACCAACAACAGAGGAGCGTGTTTTGCTAGATGAACAT
TCGGAAGACATTGATTCGCTAGCGAGAGCTGACCGATTTTTATATGAAATTTCCAAAATA
CATCATTATGAACAGCGGTTAAAAAGCTTACATTACAAGAAGCGTTTTAATGTGACCCTT
AATGACCTTTTTCCACGCATCAATAATGTAATGGAAGCTAGTCGAGAGGTCTCTCGAAGT
CGACGATTAAGGAAACTTTTAGAATTGGTGCTAGCACTAGGAAACTATATGAATCGTGGT
GCTCGTGGTCAAGCATTAGGTTTTCGCATACAATCGCTTAACAAACTTGTGGATACAAAA
GCAAATACCAAAGCGAAAGGAACAACTCTTCTTCACTATCTCGTGCAAGTAATTGAGGCA
AAACATAAAGATATATTGCGTTTGGAAGAAGACATTCCACATGTTCATATGGCTGCAAAA
GTGAGTCTTGGTGAAATGGAAAAAGATATTGCAAATTTGAGAAGTGGCTTAGCCGATGTC
GCAAGAGAAATTGAATTCCATCGAAGTGCCGGATCAAACGTTCCGGAAGATAGATTTTTA
GTTGTTATGCGTGATTTCTATGCACAAGCTTCAATTAGATTTGCTGAGTTAGAAGACAAA
TACCAAGACATGAAAACTAGATTTGATCGATGTGTAAGGTTATTTGGTGAAGATGGATCA
GTCATACAACCAGATGAATTTTTTGGCATTTTCGATCAATTCTTAGTTCAATTCAGTGAA
GCTCGTAATGATAATGAGAACTTTAAAAAGAGAGCAGAAGAAGAGGAGAAAAGAATTAAG
CAAGAAGCTGAGATGAAGAAGCGAACAATAGAGAGAAAATCAAAAGATGGATTTTTAAGC
TCAGTAGCGAAAAATTTGGGATTGAAATCAAAAGAAGAGCAACATCAACAGAAAGTCGAA
ACTAGAGAGTTTGATGATTTGATTGAAACACTGCGAACTGGTGATGTTTTCCAAGGTGAG
AAGTATAAGAGATCGAGAAAATCGAAAGCCGGCACTTCACCGCCTCGAAATCAACGTTCA
AATGGTGACAGTAATTCTCGAGAAAGAATTTTTTAA

>g11568.t1 Gene=g11568 Length=1211
MCSINTKHHFNILMDKLNLSIPSCSIPIPSAFQNLPRLCPSWCHESEDSGNNAAATTAQA
FSQSAVNLIHAPPKYHQKKMPFRKKNWCGCIQDDEPPEICVVEGVFSLENLTPTQPMPSA
EELEEKFSELVEELDLTEANKAQMMNLPSAKKWQIYCSRKIPTESIESPDGCASSTISNF
EKTPLFYVERLREITSQLRITTDDSPKHNDFQLKIEQQTALCDALKTALRTAAHSFVLKF
IESQGLAALLDTLEAVTTVFIIANSSLHTSIIGCIKALMNNSTGRSHVLQHPTSINIIAK
SLACENTKTKVAVLEILGAVCLVQGGHKKVLEAFISFQEFASERTRFQSIMNDLDRSIGS
YRDETNLKVAIMSLINALVNYGAGEDQLEFRLHLRFEFIMLGIEKTIQKLRKYENETLDR
HLDFFEMVRLEDEKELSRKFSNESIEAESAIEIFDLLRRKLNYSAAYPHFLSMLQHMMLL
PFTSSNTHYWLLFDRILQQIVLQQSDQRPSSEIESFFEEHMPSENSKPKFTNPDVTPIEI
DVNKIVKLLVREEELINARRKAEELERENLEFVAKLSKKERELDLRTAEKEDLETNLIRM
RERLEKESTNHSQAVTRAINAEMKIEDLQHKLVNEQQERLRLEKLMSEGSFPDDQKAAGL
QVNKENCNIESLNSSVPPPPPIPQCAPAPPPPACPPPPPSLKGLPMAPPLPKVEVSKKNI
PSSSQPLKSFNWSKLPELKIQNTVWSELDETKWYNSMDLESIDKLFSAYQNQKNERNGVD
GSSIEDLRLIGKGKTKILSVIDGRRAQNCTILLSKLKMTDDEISKAILSMDSNDQLPIDM
VEQLLKFTPTTEERVLLDEHSEDIDSLARADRFLYEISKIHHYEQRLKSLHYKKRFNVTL
NDLFPRINNVMEASREVSRSRRLRKLLELVLALGNYMNRGARGQALGFRIQSLNKLVDTK
ANTKAKGTTLLHYLVQVIEAKHKDILRLEEDIPHVHMAAKVSLGEMEKDIANLRSGLADV
AREIEFHRSAGSNVPEDRFLVVMRDFYAQASIRFAELEDKYQDMKTRFDRCVRLFGEDGS
VIQPDEFFGIFDQFLVQFSEARNDNENFKKRAEEEEKRIKQEAEMKKRTIERKSKDGFLS
SVAKNLGLKSKEEQHQQKVETREFDDLIETLRTGDVFQGEKYKRSRKSKAGTSPPRNQRS
NGDSNSRERIF

Protein features from InterProScan

Transcript Database ID Name Start End E.value
15 g11568.t1 Coils Coil Coil 120 140 -
16 g11568.t1 Coils Coil Coil 548 610 -
12 g11568.t1 Coils Coil Coil 618 645 -
11 g11568.t1 Coils Coil Coil 1003 1023 -
14 g11568.t1 Coils Coil Coil 1047 1067 -
13 g11568.t1 Coils Coil Coil 1098 1133 -
9 g11568.t1 Gene3D G3DSA:1.25.10.10 - 181 437 9.4E-55
10 g11568.t1 Gene3D G3DSA:1.10.238.150 - 438 519 1.0E-12
8 g11568.t1 Gene3D G3DSA:1.20.58.2220 - 735 1136 3.8E-129
20 g11568.t1 MobiDBLite mobidb-lite consensus disorder prediction 1178 1211 -
4 g11568.t1 PANTHER PTHR45725 FORMIN HOMOLOGY 2 FAMILY MEMBER 108 1179 0.0
5 g11568.t1 PANTHER PTHR45725:SF7 DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 2 108 1179 0.0
2 g11568.t1 Pfam PF06371 Diaphanous GTPase-binding Domain 117 322 1.2E-39
3 g11568.t1 Pfam PF06367 Diaphanous FH3 Domain 325 515 3.7E-56
1 g11568.t1 Pfam PF02181 Formin Homology 2 Domain 718 1098 3.0E-107
21 g11568.t1 ProSiteProfiles PS51232 Rho GTPase-binding/formin homology 3 (GBD/FH3) domain profile. 115 512 25.651
22 g11568.t1 ProSiteProfiles PS51444 Formin homology-2 (FH2) domain profile. 717 1124 74.064
17 g11568.t1 SMART SM01140 Drf_GBD_2 115 322 7.3E-52
18 g11568.t1 SMART SM01139 Drf_FH3_2 325 514 1.0E-65
19 g11568.t1 SMART SM00498 it6_source 717 1179 3.7E-132
6 g11568.t1 SUPERFAMILY SSF48371 ARM repeat 123 506 3.1E-85
7 g11568.t1 SUPERFAMILY SSF101447 Formin homology 2 domain (FH2 domain) 687 1118 2.75E-102

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0031267 small GTPase binding MF
GO:0003779 actin binding MF
GO:0016043 cellular component organization BP
GO:0030036 actin cytoskeleton organization BP

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values