Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Aldo-keto reductase family 1 member B1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g12728 g12728.t26 TTS g12728.t26 25507381 25507381
chr_1 g12728 g12728.t26 isoform g12728.t26 25507464 25508906
chr_1 g12728 g12728.t26 exon g12728.t26.exon1 25507464 25507770
chr_1 g12728 g12728.t26 cds g12728.t26.CDS1 25507727 25507770
chr_1 g12728 g12728.t26 exon g12728.t26.exon2 25507838 25508414
chr_1 g12728 g12728.t26 cds g12728.t26.CDS2 25507838 25508153
chr_1 g12728 g12728.t26 exon g12728.t26.exon3 25508839 25508906
chr_1 g12728 g12728.t26 TSS g12728.t26 25508972 25508972

Sequences

>g12728.t26 Gene=g12728 Length=952
ATGGCAGCACCTACTGTTACTCTCAATAATGGCAAACAATTTCCAATCGTTGGCCTTGGT
AATGAAAATCACCACCTGGTGTTGTTGCTCAAGCTGTAAAAGACGCAATTGATGCTGGCT
ATCGTCATTTTGACGGTGCTCATGTATATGAAAATGAGCATGAAGTTGGTGAAGGAATTA
ATGCTAAAATCGCTGAAGGTGTTATCAAACGTGAAGACGTTTTTGTAACATCAAAATTAT
GGTGCACTTTCCATGACCCAAAGGATGTTCGTGGTGCACTCGAGCATACATTGAAACAAT
TAAATTTAGATTATCTTGACTTGTACCTCATGCATTGGCCTATTTGTTATCAAAAATCAA
CTGAATTGTTCCCAAAGAATGAAGCTGGTGAAATTTTGCACGCTAATTTTGATATTCTTG
ACACTTATCGTGCAATGGAGGAACTTGTTGATGCTGGATTGACTAAAAGTATTGGAATTT
CAAACTTCAATATCAAACAAGTTGAGTACATTACTAAAAATGCTCGCATCCAACCAGTCA
CCAATCAAGTTGAATGCAATCCATATTTACTTAATAAAGAATTAAGTGATTTCTGCAAAA
GTAAAAACATTGTCATCACCGCTTATTCACCTCTTGGTTCACCAGTCAAGGTCGTCCATG
GGCAACACCAGATGACCGAGTATTATTAAAAGAACCAAAACTTTTAGAGATCGCTCAGAA
GCACAATAAAACACCAGCACAAATTTTAATCCGTTACCAAATTCAACGCGGTCACGTTGT
CATACCGAAATCAGTTACGAAGGATCGCATAATCAGTAATTTTGATGTTTTCAACTTCAC
ATTGAGCGATTCTGAAATAAAAGATTTGGAAAACTTCAACTATACTGAGCGCATTTGTAG
CATGTCTCAAGATAAACATCATCCAGCTTATCCTTTCAATGACGACGCCTAA

>g12728.t26 Gene=g12728 Length=119
MHWPICYQKSTELFPKNEAGEILHANFDILDTYRAMEELVDAGLTKSIGISNFNIKQVEY
ITKNARIQPVTNQVECNPYLLNKELSDFCKSKNIVITAYSPLGSPVKVVHGQHQMTEYY

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g12728.t26 Gene3D G3DSA:3.20.20.100 - 1 117 3.4E-41
2 g12728.t26 PANTHER PTHR11732:SF482 ZGC:56622 1 114 3.7E-36
3 g12728.t26 PANTHER PTHR11732 ALDO/KETO REDUCTASE 1 114 3.7E-36
4 g12728.t26 PRINTS PR00069 Aldo-keto reductase signature 36 53 4.4E-20
5 g12728.t26 PRINTS PR00069 Aldo-keto reductase signature 70 99 4.4E-20
1 g12728.t26 Pfam PF00248 Aldo/keto reductase family 1 104 9.6E-20
7 g12728.t26 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 36 53 -
6 g12728.t26 SUPERFAMILY SSF51430 NAD(P)-linked oxidoreductase 1 105 5.63E-31

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0047834 D-threo-aldose 1-dehydrogenase activity MF
GO:0055114 NA NA
GO:0016491 oxidoreductase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed