Gene loci information

Transcript annotation

  • This transcript has been annotated as Glutathione S-transferase 1, isoform C.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g3418 g3418.t46 TSS g3418.t46 25263104 25263104
chr_3 g3418 g3418.t46 isoform g3418.t46 25263151 25264673
chr_3 g3418 g3418.t46 exon g3418.t46.exon1 25263151 25263176
chr_3 g3418 g3418.t46 exon g3418.t46.exon2 25263334 25263430
chr_3 g3418 g3418.t46 cds g3418.t46.CDS1 25263344 25263430
chr_3 g3418 g3418.t46 exon g3418.t46.exon3 25264185 25264673
chr_3 g3418 g3418.t46 cds g3418.t46.CDS2 25264185 25264673
chr_3 g3418 g3418.t46 TTS g3418.t46 25264797 25264797

Sequences

>g3418.t46 Gene=g3418 Length=612
ATGGATTTCTACTATATGCCAGGTTAAGCCGTTCAAATGACAGCTGCAGCTGTAGGTGCT
GAATTAAACCTTAAGTTCCTCAATTTGATGGCCGGCGAACACATGAAACCAGATTTTTTA
GCAATCAATCCTCAACACACTATTCCAACTTTGGTTGACAATGGATTTGGTCTTTGGGAA
TCACGTGCTATTTGCACATATTTGATCGAGAAATACGGAAAGGAAAGTCTTTTCCCAAAA
GATCCAAAGACTCGTGCAATTATAAATCAACGTTTATACTTTGATATGGGCACGCTCTAT
CAAAAATTTGCCGACTACTACTATCCACAATTGTTTGCTAAGGCACCAGCAGATCCAGAA
AAATTCAAAGCAATGGAAACTGCCATGGGATTTTTCAATACATTTTTGGAAGGAAATAAA
TATGCTGCCGGAAATGATCTTACTGTTGCAGACATTTGTTTGGTTGCAACCATTTCCACT
TATGATGCTGCCGGTTTCGATTTGAGCAAATTCCCAAATGTTGCAAAATGGTTCGAATTG
TGCAAAAAAACTGTTCCTGGCTATGCAATCAATCAGGCTGGTGTTGATGAATTCAAGAAA
TTCTTCAATTAA

>g3418.t46 Gene=g3418 Length=191
MTAAAVGAELNLKFLNLMAGEHMKPDFLAINPQHTIPTLVDNGFGLWESRAICTYLIEKY
GKESLFPKDPKTRAIINQRLYFDMGTLYQKFADYYYPQLFAKAPADPEKFKAMETAMGFF
NTFLEGNKYAAGNDLTVADICLVATISTYDAAGFDLSKFPNVAKWFELCKKTVPGYAINQ
AGVDEFKKFFN

Protein features from InterProScan

Transcript Database ID Name Start End E.value
12 g3418.t46 CDD cd03045 GST_N_Delta_Epsilon 1 58 0.000
11 g3418.t46 CDD cd03177 GST_C_Delta_Epsilon 71 187 0.000
8 g3418.t46 Gene3D G3DSA:3.40.30.10 Glutaredoxin 1 66 0.000
7 g3418.t46 Gene3D G3DSA:1.20.1050.10 - 67 191 0.000
3 g3418.t46 PANTHER PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED 1 190 0.000
4 g3418.t46 PANTHER PTHR43969 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED 1 190 0.000
2 g3418.t46 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 56 0.000
1 g3418.t46 Pfam PF00043 Glutathione S-transferase, C-terminal domain 100 167 0.000
10 g3418.t46 ProSiteProfiles PS50404 Soluble glutathione S-transferase N-terminal domain profile. 1 64 18.031
9 g3418.t46 ProSiteProfiles PS50405 Soluble glutathione S-transferase C-terminal domain profile. 69 190 23.466
13 g3418.t46 SFLD SFLDG00358 Main (cytGST) 3 170 0.000
14 g3418.t46 SFLD SFLDS00019 Glutathione Transferase (cytosolic) 3 170 0.000
5 g3418.t46 SUPERFAMILY SSF52833 Thioredoxin-like 2 73 0.000
6 g3418.t46 SUPERFAMILY SSF47616 GST C-terminal domain-like 68 176 0.000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006749 glutathione metabolic process BP
GO:0005515 protein binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed