Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Glutathione S-transferase 1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g4877 g4877.t1 TTS g4877.t1 5701224 5701224
chr_2 g4877 g4877.t1 isoform g4877.t1 5701336 5702126
chr_2 g4877 g4877.t1 exon g4877.t1.exon1 5701336 5701857
chr_2 g4877 g4877.t1 cds g4877.t1.CDS1 5701336 5701857
chr_2 g4877 g4877.t1 exon g4877.t1.exon2 5701911 5701974
chr_2 g4877 g4877.t1 cds g4877.t1.CDS2 5701911 5701974
chr_2 g4877 g4877.t1 exon g4877.t1.exon3 5702032 5702126
chr_2 g4877 g4877.t1 cds g4877.t1.CDS3 5702032 5702126
chr_2 g4877 g4877.t1 TSS g4877.t1 5702192 5702192

Sequences

>g4877.t1 Gene=g4877 Length=681
ATGAGCAAATTGAGTTTGTATTATTCAATTATTTCACCACCATCACGATTTGCTTTGATT
GTTGCTAAAATGTTGGAATTAGATTTTGAGGAAAAAGTTGTTGATCTTCTTTCTGGTAAA
CATTTGACTGAAGAATATCGACAAATAAATCCAAGTCAAACTGTTCCGGCTTTGGTTGAT
GGTGATATGAAAATGTTTGACAGCAATGCAATTGCAATTTATTTGGTTGAAAAATATGCT
AAAGATGATTCATTGTATCCAAAAAATCTCGAACAACGTGCTAGAGTTAATGAGCAATTA
TTTTACATTGCCAGCTATCTTTTTCCAAGAGGACTTATGGTAATTAAAGGTGGCTTATCT
GGAACATTAACTGAAATTCCTCAAAAATCGATTGATGATTTTAACAGAGGCTATGAAGTA
ATCGAAAGCTTTTTAAAAAATGTGGAATATCTTTCTGGATCATCTTTGACCTTGAGTGAT
CTTTCATTGTGGTCTTTAATGGAATCAGGCGAACAAATTGTACCAATTGATGAAAATCGT
TTTCCGAATTTTGCTAAATGGATGAAGAAAATGAGACATGAAAACAAATTTAGTCAGCTT
AATAAAGAAGGTGCAGATTTGCATATTAGTATTTTTAAACAATGTCTTGAAAAAAATCGA
GCTAAAGTTAATTCAAATTAA

>g4877.t1 Gene=g4877 Length=226
MSKLSLYYSIISPPSRFALIVAKMLELDFEEKVVDLLSGKHLTEEYRQINPSQTVPALVD
GDMKMFDSNAIAIYLVEKYAKDDSLYPKNLEQRARVNEQLFYIASYLFPRGLMVIKGGLS
GTLTEIPQKSIDDFNRGYEVIESFLKNVEYLSGSSLTLSDLSLWSLMESGEQIVPIDENR
FPNFAKWMKKMRHENKFSQLNKEGADLHISIFKQCLEKNRAKVNSN

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g4877.t1 Gene3D G3DSA:3.40.30.10 Glutaredoxin 1 80 0.0000000
7 g4877.t1 Gene3D G3DSA:1.20.1050.10 - 81 223 0.0000000
3 g4877.t1 PANTHER PTHR43969:SF3 GLUTATHIONE S TRANSFERASE E11, ISOFORM A-RELATED 1 222 0.0000000
4 g4877.t1 PANTHER PTHR43969 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED 1 222 0.0000000
1 g4877.t1 Pfam PF13417 Glutathione S-transferase, N-terminal domain 6 80 0.0000000
2 g4877.t1 Pfam PF14497 Glutathione S-transferase, C-terminal domain 138 196 0.0000034
10 g4877.t1 ProSiteProfiles PS50404 Soluble glutathione S-transferase N-terminal domain profile. 2 83 22.8710000
9 g4877.t1 ProSiteProfiles PS50405 Soluble glutathione S-transferase C-terminal domain profile. 89 223 15.7630000
11 g4877.t1 SFLD SFLDG00358 Main (cytGST) 3 217 0.0000000
12 g4877.t1 SFLD SFLDG01153 Main.4: Theta-like 3 217 0.0000000
5 g4877.t1 SUPERFAMILY SSF52833 Thioredoxin-like 1 88 0.0000000
6 g4877.t1 SUPERFAMILY SSF47616 GST C-terminal domain-like 84 204 0.0000000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006749 glutathione metabolic process BP
GO:0005515 protein binding MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values