General information for g519.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Farnesol dehydrogenase.
Parent gene
- The parent gene g519 is located on chr_3: 3869122..3870018 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g519 | g519.t1 | TSS | g519.t1 | 3869009 | 3869009 |
| chr_3 | g519 | g519.t1 | isoform | g519.t1 | 3869122 | 3870018 |
| chr_3 | g519 | g519.t1 | exon | g519.t1.exon1 | 3869122 | 3869171 |
| chr_3 | g519 | g519.t1 | cds | g519.t1.CDS1 | 3869122 | 3869171 |
| chr_3 | g519 | g519.t1 | exon | g519.t1.exon2 | 3869236 | 3869764 |
| chr_3 | g519 | g519.t1 | cds | g519.t1.CDS2 | 3869236 | 3869764 |
| chr_3 | g519 | g519.t1 | exon | g519.t1.exon3 | 3869818 | 3870018 |
| chr_3 | g519 | g519.t1 | cds | g519.t1.CDS3 | 3869818 | 3870018 |
| chr_3 | g519 | g519.t1 | TTS | g519.t1 | 3870053 | 3870053 |
Sequences
>g519.t1 Gene=g519 Length=780
ATGACAATTTCACGATGGTCTGGTCGTGTTGCGGTTGTGACGGGAGCAAGCGCTGGAATT
GGTGCTGCAACTGCAATAGAATTAGCTAAAAATGGTTTGATCACAATCGGATTAGCGAGA
AGAGTCGAAAAAATTGAAGAACTTCGATCACAATTGACATCAGATCAACAGAAAAATTTT
CATGCCATGAAATGTGATGTTTCAGTTGAAGCTGAAATTGTTAGAACTTTTTCTGACATT
GTTAAGAAATTTGGTGGAATTGATGTCTTAATTAATAACGCTGCTTTTATGACGCTAACA
AAATTGATTGATTTGGAAAATTCAAGTGAATTTCAAAAAGTTTTCGAAGTTAATGTATTC
GGTGTCATAAATTGTACAAGAGAATTTGTGAAGTCAATTCGTGAAAGAAATGCTGAAGGT
CATGTAATTCATATTAATAGCATCCTTGGTCATGTTATGCCTTTTTATCTTGAACATCCT
ACTTTTGGAGTCTATAGTGCAAGTAAATTTGCAGTCACAGCTTTGGCAGAGCAACATCGA
CAAGAATTTATTAAAGAAAAACTGAACATTAAAGTCACATCTTTAAGTCCAGGATTTGTT
GCAACCGAAATGCTAGGGAATATTATGAAATTGTCTAAAGAACAAATTGAAAAATACTTA
GAAAAATATCCACATTTGCTGCCTAAAGATATTGCTGATGCCATTATTTATTTATTGAGC
ACACCACAAAATGTTTTAGTTACAGAGCTCACAATTAGACCAATGAATGAAAGTTCTTAA
>g519.t1 Gene=g519 Length=259
MTISRWSGRVAVVTGASAGIGAATAIELAKNGLITIGLARRVEKIEELRSQLTSDQQKNF
HAMKCDVSVEAEIVRTFSDIVKKFGGIDVLINNAAFMTLTKLIDLENSSEFQKVFEVNVF
GVINCTREFVKSIRERNAEGHVIHINSILGHVMPFYLEHPTFGVYSASKFAVTALAEQHR
QEFIKEKLNIKVTSLSPGFVATEMLGNIMKLSKEQIEKYLEKYPHLLPKDIADAIIYLLS
TPQNVLVTELTIRPMNESS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 15 | g519.t1 | Gene3D | G3DSA:3.40.50.720 | - | 2 | 257 | 2.5E-63 |
| 2 | g519.t1 | PANTHER | PTHR43115 | DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 | 4 | 257 | 4.4E-98 |
| 3 | g519.t1 | PANTHER | PTHR43115:SF4 | DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 | 4 | 257 | 4.4E-98 |
| 8 | g519.t1 | PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 10 | 27 | 1.1E-25 |
| 5 | g519.t1 | PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 85 | 96 | 4.7E-7 |
| 11 | g519.t1 | PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 85 | 96 | 1.1E-25 |
| 10 | g519.t1 | PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 134 | 150 | 1.1E-25 |
| 6 | g519.t1 | PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 140 | 148 | 4.7E-7 |
| 4 | g519.t1 | PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 165 | 184 | 4.7E-7 |
| 7 | g519.t1 | PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 165 | 184 | 1.1E-25 |
| 12 | g519.t1 | PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 188 | 205 | 1.1E-25 |
| 9 | g519.t1 | PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 221 | 241 | 1.1E-25 |
| 1 | g519.t1 | Pfam | PF00106 | short chain dehydrogenase | 10 | 208 | 4.5E-47 |
| 17 | g519.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 25 | - |
| 18 | g519.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 9 | - |
| 19 | g519.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 10 | 20 | - |
| 20 | g519.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 21 | 25 | - |
| 16 | g519.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 26 | 259 | - |
| 14 | g519.t1 | ProSitePatterns | PS00061 | Short-chain dehydrogenases/reductases family signature. | 152 | 180 | - |
| 13 | g519.t1 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 3 | 246 | 1.32E-58 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
Data is missing for g519/g519.t1; file /home/yuki.yoshida/nias/analysis/reanalysis/18_revice/midgebase/iupred3/g519.t1.fa.iupred3.txt does not exist
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K22970 (17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
