Gene loci information

Transcript annotation

  • This transcript has been annotated as Retinol dehydrogenase 14.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g6775 g6775.t1 TSS g6775.t1 18562263 18562263
chr_2 g6775 g6775.t1 isoform g6775.t1 18562371 18563461
chr_2 g6775 g6775.t1 exon g6775.t1.exon1 18562371 18562444
chr_2 g6775 g6775.t1 cds g6775.t1.CDS1 18562371 18562444
chr_2 g6775 g6775.t1 exon g6775.t1.exon2 18562521 18562768
chr_2 g6775 g6775.t1 cds g6775.t1.CDS2 18562521 18562768
chr_2 g6775 g6775.t1 exon g6775.t1.exon3 18562887 18563461
chr_2 g6775 g6775.t1 cds g6775.t1.CDS3 18562887 18563461
chr_2 g6775 g6775.t1 TTS g6775.t1 18563567 18563567

Sequences

>g6775.t1 Gene=g6775 Length=897
ATGGACTGGTGGCTCATTCTATTAATTATAATTTTAGTGTTATTAGGAATTTTTGCTCTT
TTGTATTTATTAAAATTATACATTAGACGAGCAAGATTCACTAAAACTACTAGAATTACT
GATAAAATTGTAATCATCACTGGTGCAAATACAGGCATCGGAAAAGAGACTGCCATTGAC
TTGGCAAAACGAGGTGGGAAAATTTATATTGTATGTCGCGATCAAAAACGCGGTGAGGAT
GCATTGAAAGAAATAAAAGAAAGAAGTGGCAGTGACAAAGTTCATTTCATGCAACTTGAT
CTGGCTTCTCTAGAATCTGTTCGTGTAATGGCCTGTCCAAAATCATATACAGCTGATGGA
TATGAATTGCAATTTGGAACTAATCATTTAGGGCATTTTCTGCTCACAAATTTATTGCTT
GATTTGTTAAAAGCCGGCGCACCGAGTCGAATAGTAGTTGTGTCTAGTGCTGCATATCAA
ATCGGTAGAATAAATAAAGAAGATTTGATGTATGAAAAGAGTTACAATAAATACAAAGCT
TATGGGCAAAGTAAACTTGCAAACATTCTATTTACACGTGAATTAGCAAAACGACTTGAT
GGCACAGGTGTCAATGTCAATAGCTGTCATCCTGGCGTTGTTCAAACTGAATTAGGAAGA
TATATGGATGAAAATATTCGAAAGTATTTTATCAAACCTATTTTAGGTCCATTTTTTAAA
ATTCCATATGAAGGAGCCCAAACTCAAATTCGATTAGCTGTTGATCCTGATTTAGATAAA
GTGACAGGAAAATATTTTGCCGATTGCAAAGAACATTCACTAAGAAGTAATGCACAATGT
GAAGAAATTGCAGAATGGCTGTGGAAAAAAAGTGCTGAATTTGTGGGACCTTGTTAA

>g6775.t1 Gene=g6775 Length=298
MDWWLILLIIILVLLGIFALLYLLKLYIRRARFTKTTRITDKIVIITGANTGIGKETAID
LAKRGGKIYIVCRDQKRGEDALKEIKERSGSDKVHFMQLDLASLESVRVMACPKSYTADG
YELQFGTNHLGHFLLTNLLLDLLKAGAPSRIVVVSSAAYQIGRINKEDLMYEKSYNKYKA
YGQSKLANILFTRELAKRLDGTGVNVNSCHPGVVQTELGRYMDENIRKYFIKPILGPFFK
IPYEGAQTQIRLAVDPDLDKVTGKYFADCKEHSLRSNAQCEEIAEWLWKKSAEFVGPC

Protein features from InterProScan

Transcript Database ID Name Start End E.value
13 g6775.t1 Gene3D G3DSA:3.40.50.720 - 29 297 8.5E-74
4 g6775.t1 PANTHER PTHR24320 RETINOL DEHYDROGENASE 9 108 2.7E-116
6 g6775.t1 PANTHER PTHR24320:SF142 GH10714P-RELATED 9 108 2.7E-116
3 g6775.t1 PANTHER PTHR24320 RETINOL DEHYDROGENASE 109 296 2.7E-116
5 g6775.t1 PANTHER PTHR24320:SF142 GH10714P-RELATED 109 296 2.7E-116
9 g6775.t1 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 43 60 5.7E-13
8 g6775.t1 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 5.7E-13
10 g6775.t1 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 200 5.7E-13
7 g6775.t1 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 219 5.7E-13
1 g6775.t1 Pfam PF00106 short chain dehydrogenase 42 108 2.3E-12
2 g6775.t1 Pfam PF00106 short chain dehydrogenase 121 224 8.7E-12
15 g6775.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 1 5 -
16 g6775.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 6 28 -
14 g6775.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 29 298 -
12 g6775.t1 SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains 40 273 6.67E-51
11 g6775.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 4 26 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

## [1] "No matching GO terms"

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values