Gene loci information

Transcript annotation

  • This transcript has been annotated as Histone H2A.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g6804 g6804.t1 TSS g6804.t1 18829151 18829151
chr_2 g6804 g6804.t1 isoform g6804.t1 18829950 18830938
chr_2 g6804 g6804.t1 exon g6804.t1.exon1 18829950 18829982
chr_2 g6804 g6804.t1 cds g6804.t1.CDS1 18829950 18829982
chr_2 g6804 g6804.t1 exon g6804.t1.exon2 18830552 18830938
chr_2 g6804 g6804.t1 cds g6804.t1.CDS2 18830552 18830938
chr_2 g6804 g6804.t1 TTS g6804.t1 18830917 18830917

Sequences

>g6804.t1 Gene=g6804 Length=420
ATGATTGAAATTTCTTCATATAAAATACTAGTCCAAAAATGTCAGGACGAGGCAAAAGGA
GGAAAAGTTAAGGCAAAGGCAAAGTCACGATCAAGTCGTGCTGGACTTCAATTCCCAGTC
GGTCGTATTCATCGTCTTCTACGCAAAGGAAACTATGGTGAACGTGTTGGTGCTGGTGCT
CCAGTATATTTGGCTGCTGTCATGGAATATTTGGCTGCTGAAGTTCTTGAATTGGCAGGA
AATGCTGCTCGTGATAACAAAAAGACAAGAATCATCCCACGTCACTTGCAATTGGCCATC
CGTAATGACGAAGAATTGAATAAACTTCTCTCAGGCGTCACAATCGCTCAAGGTGGTGTT
TTGCCAAACATTCAGGCCGTCTTGTTGCCAAAGAAGACCGAAACAAAGAAAACAGCTTAA

>g6804.t1 Gene=g6804 Length=139
MIEISSYKILVQKCQDEAKGGKVKAKAKSRSSRAGLQFPVGRIHRLLRKGNYGERVGAGA
PVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGV
LPNIQAVLLPKKTETKKTA

Protein features from InterProScan

Transcript Database ID Name Start End E.value
12 g6804.t1 CDD cd00074 H2A 29 132 8.95674E-70
11 g6804.t1 Gene3D G3DSA:1.10.20.10 Histone 15 139 1.0E-66
3 g6804.t1 PANTHER PTHR23430:SF222 HISTONE H2A 17 136 2.7E-72
4 g6804.t1 PANTHER PTHR23430 HISTONE H2A 17 136 2.7E-72
9 g6804.t1 PRINTS PR00620 Histone H2A signature 26 48 2.0E-55
5 g6804.t1 PRINTS PR00620 Histone H2A signature 55 70 2.0E-55
6 g6804.t1 PRINTS PR00620 Histone H2A signature 70 83 2.0E-55
8 g6804.t1 PRINTS PR00620 Histone H2A signature 84 98 2.0E-55
7 g6804.t1 PRINTS PR00620 Histone H2A signature 112 130 2.0E-55
2 g6804.t1 Pfam PF00125 Core histone H2A/H2B/H3/H4 21 101 6.6E-16
1 g6804.t1 Pfam PF16211 C-terminus of histone H2A 104 137 8.8E-21
13 g6804.t1 ProSitePatterns PS00046 Histone H2A signature. 34 40 -
14 g6804.t1 SMART SM00414 h2a4 15 135 3.6E-80
10 g6804.t1 SUPERFAMILY SSF47113 Histone-fold 28 132 7.19E-46

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0003677 DNA binding MF
GO:0046982 protein heterodimerization activity MF
GO:0000786 nucleosome CC

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values