General information for g6925.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Dual specificity protein phosphatase 14.
Parent gene
- The parent gene g6925 is located on chr_2: 20008106..20012561 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6925 | g6925.t1 | TTS | g6925.t1 | 20007861 | 20007861 |
| chr_2 | g6925 | g6925.t1 | isoform | g6925.t1 | 20008106 | 20012561 |
| chr_2 | g6925 | g6925.t1 | exon | g6925.t1.exon1 | 20008106 | 20008685 |
| chr_2 | g6925 | g6925.t1 | cds | g6925.t1.CDS1 | 20008106 | 20008685 |
| chr_2 | g6925 | g6925.t1 | exon | g6925.t1.exon2 | 20012398 | 20012561 |
| chr_2 | g6925 | g6925.t1 | cds | g6925.t1.CDS2 | 20012398 | 20012561 |
| chr_2 | g6925 | g6925.t1 | TSS | g6925.t1 | 20012784 | 20012784 |
Sequences
>g6925.t1 Gene=g6925 Length=744
ATGATGAAGACTCTAACAATGCCTACGGCACCAGCCACAGATGATAATTTGCGAATATTA
ACATCGGCGACAGATGACAAGCAATCCACAAAAATCCAGCAATTACTCGGTTTAAACAAT
ACTACTGAAAATATGAATAGCAATACAAACATCGTTCCATCAAGCAATCAGGTGCCTTTT
TATTTTGGAATATCAGAAATTCTGCCCACACTTTATCTTTGCGGAGCGTGTGCTGTTGTG
AGACCAGAAACACTTGAACAGTTGGAAATTAAATTTGTCATAAATGCCACAGTTGAATTG
CCAGATACACCTTTACCCGATGACCGACCTGAGTATATGCGAGTTCCAATTAAAGATGTA
CGTGAATCAAATTTAATTGAATTTTTTGATCAAGTTGCTGACAAAATTGAAAAGACAAGA
AAAAAAGATGGTAAAAGTTTGGTACATTGTGTTGCTGGTGTTTCACGATCAGCATCTTTG
GTGATTGCTTATCTCATGAAGTATTCCAATATGTCACTGAAGCAAGCATTCCATCATGTG
CGTAGCATTAGGCCTCAAGTGAGACCTAATGTTGGTTTCTTCAAACAACTTATTGAATAT
GAACAACGACTTTTTAACACAACAACAGTATCAATGGTTCATTGTAATTCGCTAGGCGAA
GAAATTCCTGATGTTTATGAATCAGAATATAAAGCTATGGAATTGCTTTATCAAAAATAT
CGAAGAAGTTTCGCTAGACGATAA
>g6925.t1 Gene=g6925 Length=247
MMKTLTMPTAPATDDNLRILTSATDDKQSTKIQQLLGLNNTTENMNSNTNIVPSSNQVPF
YFGISEILPTLYLCGACAVVRPETLEQLEIKFVINATVELPDTPLPDDRPEYMRVPIKDV
RESNLIEFFDQVADKIEKTRKKDGKSLVHCVAGVSRSASLVIAYLMKYSNMSLKQAFHHV
RSIRPQVRPNVGFFKQLIEYEQRLFNTTTVSMVHCNSLGEEIPDVYESEYKAMELLYQKY
RRSFARR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g6925.t1 | CDD | cd14514 | DUSP14-like | 64 | 199 | 1.65491E-67 |
| 5 | g6925.t1 | Gene3D | G3DSA:3.90.190.10 | Protein tyrosine phosphatase superfamily | 62 | 236 | 2.6E-52 |
| 2 | g6925.t1 | PANTHER | PTHR45961:SF6 | IP21249P | 63 | 238 | 2.4E-62 |
| 3 | g6925.t1 | PANTHER | PTHR45961 | IP21249P | 63 | 238 | 2.4E-62 |
| 1 | g6925.t1 | Pfam | PF00782 | Dual specificity phosphatase, catalytic domain | 71 | 202 | 1.6E-37 |
| 6 | g6925.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 146 | - |
| 8 | g6925.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 147 | 166 | - |
| 7 | g6925.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 167 | 247 | - |
| 10 | g6925.t1 | ProSitePatterns | PS00383 | Tyrosine specific protein phosphatases active site. | 148 | 158 | - |
| 13 | g6925.t1 | ProSiteProfiles | PS50054 | Dual specificity protein phosphatase family profile. | 63 | 205 | 40.289 |
| 14 | g6925.t1 | ProSiteProfiles | PS50056 | Tyrosine specific protein phosphatases family profile. | 126 | 185 | 14.5 |
| 12 | g6925.t1 | SMART | SM00195 | dsp_5 | 63 | 203 | 4.1E-47 |
| 11 | g6925.t1 | SMART | SM00404 | ptp_7 | 91 | 203 | 0.0017 |
| 4 | g6925.t1 | SUPERFAMILY | SSF52799 | (Phosphotyrosine protein) phosphatases II | 57 | 207 | 2.86E-39 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008138 | protein tyrosine/serine/threonine phosphatase activity | MF |
| GO:0006470 | protein dephosphorylation | BP |
| GO:0016311 | dephosphorylation | BP |
| GO:0004725 | protein tyrosine phosphatase activity | MF |
| GO:0016791 | phosphatase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K14165 (atypical dual specificity phosphatase)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed