Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Dual specificity protein phosphatase 21.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g6925 g6925.t3 TTS g6925.t3 20007861 20007861
chr_2 g6925 g6925.t3 isoform g6925.t3 20008106 20008683
chr_2 g6925 g6925.t3 exon g6925.t3.exon1 20008106 20008683
chr_2 g6925 g6925.t3 cds g6925.t3.CDS1 20008106 20008513
chr_2 g6925 g6925.t3 TSS g6925.t3 NA NA

Sequences

>g6925.t3 Gene=g6925 Length=578
ATCAGGTGCCTTTTTATTTTGGAATATCAGAAATTCTGCCCACACTTTATCTTTGCGGAG
CGTGTGCTGTTGTGAGACCAGAAACACTTGAACAGTTGGAAATTAAATTTGTCATAAATG
CCACAGTTGAATTGCCAGATACACCTTTACCCGATGACCGACCTGAGTATATGCGAGTTC
CAATTAAAGATGTACGTGAATCAAATTTAATTGAATTTTTTGATCAAGTTGCTGACAAAA
TTGAAAAGACAAGAAAAAAAGATGGTAAAAGTTTGGTACATTGTGTTGCTGGTGTTTCAC
GATCAGCATCTTTGGTGATTGCTTATCTCATGAAGTATTCCAATATGTCACTGAAGCAAG
CATTCCATCATGTGCGTAGCATTAGGCCTCAAGTGAGACCTAATGTTGGTTTCTTCAAAC
AACTTATTGAATATGAACAACGACTTTTTAACACAACAACAGTATCAATGGTTCATTGTA
ATTCGCTAGGCGAAGAAATTCCTGATGTTTATGAATCAGAATATAAAGCTATGGAATTGC
TTTATCAAAAATATCGAAGAAGTTTCGCTAGACGATAA

>g6925.t3 Gene=g6925 Length=135
MRVPIKDVRESNLIEFFDQVADKIEKTRKKDGKSLVHCVAGVSRSASLVIAYLMKYSNMS
LKQAFHHVRSIRPQVRPNVGFFKQLIEYEQRLFNTTTVSMVHCNSLGEEIPDVYESEYKA
MELLYQKYRRSFARR

Protein features from InterProScan

Transcript Database ID Name Start End E.value
9 g6925.t3 CDD cd14514 DUSP14-like 1 87 8.98988E-49
5 g6925.t3 Gene3D G3DSA:3.90.190.10 Protein tyrosine phosphatase superfamily 1 124 1.7E-40
2 g6925.t3 PANTHER PTHR45961:SF6 IP21249P 1 126 5.1E-49
3 g6925.t3 PANTHER PTHR45961 IP21249P 1 126 5.1E-49
1 g6925.t3 Pfam PF00782 Dual specificity phosphatase, catalytic domain 1 90 1.1E-31
6 g6925.t3 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 1 34 -
8 g6925.t3 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 35 54 -
7 g6925.t3 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 55 135 -
10 g6925.t3 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 36 46 -
12 g6925.t3 ProSiteProfiles PS50054 Dual specificity protein phosphatase family profile. 1 93 33.506
13 g6925.t3 ProSiteProfiles PS50056 Tyrosine specific protein phosphatases family profile. 14 73 14.5
11 g6925.t3 SMART SM00195 dsp_5 1 91 2.0E-18
4 g6925.t3 SUPERFAMILY SSF52799 (Phosphotyrosine protein) phosphatases II 2 95 3.14E-30

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0008138 protein tyrosine/serine/threonine phosphatase activity MF
GO:0006470 protein dephosphorylation BP
GO:0016311 dephosphorylation BP
GO:0004725 protein tyrosine phosphatase activity MF
GO:0016791 phosphatase activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed