Gene loci information

Transcript annotation

  • This transcript has been annotated as Peroxiredoxin-4.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g7608 g7608.t16 TTS g7608.t16 24908670 24908670
chr_2 g7608 g7608.t16 isoform g7608.t16 24908768 24911301
chr_2 g7608 g7608.t16 exon g7608.t16.exon1 24908768 24908843
chr_2 g7608 g7608.t16 cds g7608.t16.CDS1 24908791 24908843
chr_2 g7608 g7608.t16 exon g7608.t16.exon2 24910220 24910599
chr_2 g7608 g7608.t16 cds g7608.t16.CDS2 24910220 24910599
chr_2 g7608 g7608.t16 exon g7608.t16.exon3 24910658 24910850
chr_2 g7608 g7608.t16 cds g7608.t16.CDS3 24910658 24910850
chr_2 g7608 g7608.t16 exon g7608.t16.exon4 24910934 24911032
chr_2 g7608 g7608.t16 cds g7608.t16.CDS4 24910934 24911021
chr_2 g7608 g7608.t16 exon g7608.t16.exon5 24911185 24911301
chr_2 g7608 g7608.t16 TSS g7608.t16 24911300 24911300

Sequences

>g7608.t16 Gene=g7608 Length=865
CAGTGTATTTGTGAGATTTATAAACCAAATTTAGTCTCTCATTAGAAATAGAAATTTACT
AGAAATAAGCATTGATTTATATAGAAAAATCGTTTAAACAGCTACCTCAATAAAAAATTG
GCGCAAAAATGCTGAAGCATTTTGTTATTTTCTCCTTCGTACTCTTTGGATTAGCTTTTG
CAAATGACGATGGTTCATGCTTTGCAGCCCCAAAAGATGTGTACCCAACTGATAAAAGTT
CTAATAAAATTGAACACAGTTTGCAATATACTAAGGCAGTGATCTCAAAGCCTGCACCTC
AATTTTCTGGCACAGCTGTTATGAATGGAGAATTTAAAACAATAAGTTTGAATGATTATC
TTGGAAAATATGTAGTTTTCTTCTTCTATCCTTTGGATTTCACATTTGTATGCCCAACAG
AAATTTTGGCATTTAGCGATAGAATTGATGAATTTAAAAAGATTAACACGGAAGTTATTG
CTGCTTCAGTTGATTCTCATTTTACACATCTATCATGGACAAAGACACCAAGAAAAGAAG
GTGGTTTAGGAAATGTGAAAATTCCTTTGCTGAGCGATTTATCGCATAAAATATCTAAAG
ATTATGGAGTTTATTTGGAGGATCTTGGCCATACACTTAGAGGACTTTTCATTATTGATG
CAAAAGGTGTTTTACGTCAGATTACAATGAATGATTTGCCAGTTGGACGTAGTGTCGATG
AAACTCTTCGTTTGGTACAAGCTTTTCAATATACTGATACTCATGGTGAAGGTGAGTTAT
TATACACGATGGCTGGATGCCGGGATCTAGAACCATCATCCCTGATCCTGAGGAGAAGCT
AAAATACTTTGAGAAAGAGTTATGA

>g7608.t16 Gene=g7608 Length=237
MLKHFVIFSFVLFGLAFANDDGSCFAAPKDVYPTDKSSNKIEHSLQYTKAVISKPAPQFS
GTAVMNGEFKTISLNDYLGKYVVFFFYPLDFTFVCPTEILAFSDRIDEFKKINTEVIAAS
VDSHFTHLSWTKTPRKEGGLGNVKIPLLSDLSHKISKDYGVYLEDLGHTLRGLFIIDAKG
VLRQITMNDLPVGRSVDETLRLVQAFQYTDTHGEGELLYTMAGCRDLEPSSLILRRS

Protein features from InterProScan

Transcript Database ID Name Start End E.value
13 g7608.t16 CDD cd03015 PRX_Typ2cys 52 214 3.55141E-107
7 g7608.t16 Gene3D G3DSA:3.40.30.10 Glutaredoxin 46 225 3.4E-79
2 g7608.t16 PANTHER PTHR10681 THIOREDOXIN PEROXIDASE 24 214 2.1E-108
3 g7608.t16 PANTHER PTHR10681:SF157 PEROXIREDOXIN-4 24 214 2.1E-108
1 g7608.t16 Pfam PF00578 AhpC/TSA family 52 184 2.1E-36
9 g7608.t16 Phobius SIGNAL_PEPTIDE Signal peptide region 1 26 -
10 g7608.t16 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide. 1 5 -
11 g7608.t16 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide. 6 17 -
12 g7608.t16 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide. 18 26 -
8 g7608.t16 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 27 237 -
15 g7608.t16 ProSiteProfiles PS51352 Thioredoxin domain profile. 50 208 17.029
4 g7608.t16 SUPERFAMILY SSF52833 Thioredoxin-like 52 214 5.74E-59
6 g7608.t16 SignalP_EUK SignalP-noTM SignalP-noTM 1 18 -
14 g7608.t16 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM 1 18 -
5 g7608.t16 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM 1 26 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016209 antioxidant activity MF
GO:0055114 NA NA
GO:0016491 oxidoreductase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed