ko00280: Valine, leucine and isoleucine degradation

Genes annotated with KAAS are mapped onto the ko00280 map with pathview. genes colored in red are conserved in P. vanderplanki.

Orthologs for this pathway

  • K00020
    • EC:1.1.1.31: 3-hydroxyisobutyrate dehydrogenase
    • g4451, g7588
  • K00022
    • EC:1.1.1.35: 3-hydroxyacyl-CoA dehydrogenase
    • g8419
  • K00128
  • K00140
    • EC:1.2.1.18: malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase
    • g823
  • K00140
    • EC:1.2.1.27: malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase
    • g823
  • K00166
    • EC:1.2.4.4: 2-oxoisovalerate dehydrogenase E1 component alpha subunit
    • g9554
  • K00167
    • EC:1.2.4.4: 2-oxoisovalerate dehydrogenase E1 component beta subunit
    • g16960
  • K00248
    • EC:1.3.8.1: butyryl-CoA dehydrogenase
    • g14410
  • K00249
    • EC:1.3.8.7: acyl-CoA dehydrogenase
    • g17272
  • K00253
    • EC:1.3.8.4: isovaleryl-CoA dehydrogenase
    • g7635, g7636
  • K00382
    • EC:1.8.1.4: dihydrolipoamide dehydrogenase
    • g2842
  • K00626
    • EC:2.3.1.9: acetyl-CoA C-acetyltransferase
    • g9594, g423
  • K00632
    • EC:2.3.1.16: acetyl-CoA acyltransferase
    • g2985
  • K00826
    • EC:2.6.1.42: branched-chain amino acid aminotransferase
    • g14017
  • K00827
    • EC:2.6.1.40: alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase
    • g9242
  • K00827
    • EC:2.6.1.44: alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase
    • g9242
  • K01027
  • K01028
    • EC:2.8.3.5: 3-oxoacid CoA-transferase subunit A
    • g8184, g15755
  • K01640
    • EC:4.1.3.4: hydroxymethylglutaryl-CoA lyase
    • g13288, g13289
  • K01641
    • EC:2.3.3.10: hydroxymethylglutaryl-CoA synthase
    • g3690
  • K01692
    • EC:4.2.1.17: enoyl-CoA hydratase
    • g3891
  • K01968
    • EC:6.4.1.4: 3-methylcrotonyl-CoA carboxylase alpha subunit
    • g13674
  • K01969
    • EC:6.4.1.4: 3-methylcrotonyl-CoA carboxylase beta subunit
    • g15546
  • K05605
    • EC:3.1.2.4: 3-hydroxyisobutyryl-CoA hydrolase
    • g14284, g14460
  • K05607
    • EC:4.2.1.18: methylglutaconyl-CoA hydratase
    • g13132
  • K07508
    • EC:2.3.1.16: acetyl-CoA acyltransferase 2
    • g3180
  • K07509
    • EC:2.3.1.16: acetyl-CoA acyltransferase
    • g2985
  • K07511
    • EC:4.2.1.17: enoyl-CoA hydratase
    • g3891
  • K07515
    • EC:4.2.1.17: enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase
    • g9117
  • K07515
    • EC:1.1.1.211: enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase
    • g9117
  • K08683
    • EC:1.1.1.35: 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
    • g332
  • K08683
    • EC:1.1.1.178: 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
    • g332
  • K09478
    • EC:1.3.8.5: short-chain 2-methylacyl-CoA dehydrogenase
    • g12936, g12935
  • K09699
    • EC:2.3.1.168: 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase)
    • g9924
  • K13524
    • EC:2.6.1.19: 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase
    • g9942
  • K13524
    • EC:2.6.1.22: 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase
    • g9942
  • K14085
    • EC:1.2.1.3: aldehyde dehydrogenase family 7 member A1
    • g13028
  • K14085
    • EC:1.2.1.8: aldehyde dehydrogenase family 7 member A1
    • g13028
  • K14085
    • EC:1.2.1.31: aldehyde dehydrogenase family 7 member A1
    • g13028
  • K18660
  • K23146
    • EC:1.1.1.31: 3-hydroxyisobutyrate/3-hydroxypropionate dehydrogenase
    • g7588
  • K23146
    • EC:1.1.1.59: 3-hydroxyisobutyrate/3-hydroxypropionate dehydrogenase
    • g7588