ko01521: EGFR tyrosine kinase inhibitor resistance

Genes annotated with KAAS are mapped onto the ko01521 map with pathview. genes colored in red are conserved in P. vanderplanki.

Orthologs for this pathway

  • K00922
    • EC:2.7.1.153: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
    • g12521
  • K01110
    • EC:3.1.3.16: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
    • g5232
  • K01110
    • EC:3.1.3.48: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
    • g5232
  • K01110
    • EC:3.1.3.67: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
    • g5232
  • K01116
    • EC:3.1.4.11: phosphatidylinositol phospholipase C, gamma-1
    • g10026
  • K02649
  • K02677
    • EC:2.7.11.13: classical protein kinase C alpha type
    • g14087
  • K02991
  • K03083
    • EC:2.7.11.26: glycogen synthase kinase 3 beta
    • g10412
  • K03099
  • K03259
  • K04361
    • EC:2.7.10.1: epidermal growth factor receptor
    • g5568
  • K04364
  • K04365
    • EC:2.7.11.1: B-Raf proto-oncogene serine/threonine-protein kinase
    • g8869
  • K04368
    • EC:2.7.12.2: mitogen-activated protein kinase kinase 1
    • g2128
  • K04371
    • EC:2.7.11.24: mitogen-activated protein kinase 1/3
    • g9093
  • K04447
    • EC:2.7.10.2: Janus kinase 2
    • g4919
  • K04456
    • EC:2.7.11.1: RAC serine/threonine-protein kinase
    • g11018, g11019
  • K04688
    • EC:2.7.11.1: ribosomal protein S6 kinase beta
    • g11364
  • K05087
    • EC:2.7.10.1: insulin-like growth factor 1 receptor
    • g16541, g17037
  • K05093
    • EC:2.7.10.1: fibroblast growth factor receptor 2
    • g2994
  • K05704
  • K06279
  • K07203
    • EC:2.7.11.1: serine/threonine-protein kinase mTOR
    • g13452
  • K07827
  • K09408